3 results for “antiulcer”

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Research ArticleOpen accessEvery word in the titleStudies on Wound Healing and Antiulcer Activities of Extract of Aerial Parts of Phyllanthus niruri L. (Euphorbiaceae)C. O. Okoli, A. C. Ezike, P. A. Akah et al.Problem statement: Phyllanthus niruri is widely used in many parts of the world to manage a wide range of diseases. As part of efforts to elucidate its pharmacological activities and hence medicinal potential, we studied the wound healing and antiulcer properties of extract of the aerial parts using experimentally-created wounds and ulcers in rodents. Approach: Wound healing effect was assessed … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 10,091 accessesView PDF Cite

Research ArticleOpen accessIn the abstractGastroprotective Effects of β-sitosterol and β-sitosterol-3-O-β-D-glucopyranoside from Bridelia ferruginea Stem BarkEjike Marcellus Nnamani, Peter Achunike Akah, Charles Ogbonnaya Okoli et al.The methanol extract of Bridelia ferruginea Benth. (Euphorbiaceae) stem bark (BFME) was partitioned in chloroform-methanol-water (2:2:1) mixture to obtain the Chloroform (CF) and Aqueous Methanol (AMF) fractions. The BFME, CF and AMF were screened for antiulcer activity using indomethacin-induced ulcer as activity guide. The CF provided the highest gastroprotection and was subsequently fractionated in a silica gel (60-200 mesh) column … …American Journal of Pharmacology and Toxicology, Vol. 15, Issue 1 · 4 Jan 2021 · 7,784 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAcute and Sub-Acute Toxicological Assessment of Aqueous Leaf Extract of Bryophyllum Pinnatum (Lam.) in Sprague-Dawley RatsRaymond Iduojemu Ozolua, Sylvester Eshiotseme Idogun, Glory Eshiagiamhe TafamelProblem statement: The aqueous leaf extract of Bryophyllum pinnatum has been reported to possess antihypertensive, antiinflammatory, antimicrobial, antidiabetic and antiulcer properties among others. Being readily available and easy to cultivate, the use of the plant in herbal medicine has been on the increase. Although there are few toxicological reports on the extract, these have not been sufficiently extensive. We therefore … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 3 · 30 Sep 2010 · 9,379 accessesView PDF Cite