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115 articles for “antibody”
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Research NotesOpen accessEvery word in the titleEvaluation of A Rapid IgM-IgG Combined Antibody Test for SARS-CoV-2 Infection: Single Italian Center StudyKatia Margiotti, Marina Cupellaro, Sabrina Emili et al.The need for timely establishment of diagnostic assays of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is demanded in laboratories worldwide. We evaluated the performance of a flow immunoassay which can detect IgM an IgG antibodies simultaneously against SARS-CoV-2 virus in human blood within 15 min. Among the 132 positive novel Coronavirus Disease 19 (COVID-19) cases, 126 tests were consistent … …American Journal of Infectious Diseases, Vol. 16, Issue 2 · 22 Jun 2020 · 7,610 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCombination of Serological Tests (Anti-CCP Antibody, Rheumatoid Factor IgM ELISA and Latex Test) are more Useful in Detection of Rheumatoid ArthritisAnindya Das, Chimanjita Phukan, Chitralekha BaruahRheumatoid arthritis is a polyarticular and chronic inflammatory disease occurring throughout the world. To prevent significant joint damage, early diagnosis and proper treatment is of paramount importance. Though patients are diagnosed clinically supported by radiography and serological tests, early disease may present with non-specific arthritis and absence of specific radiographic findings. Though anti-CCP antibody is used for the diagnosis and … …American Journal of Immunology, Vol. 13, Issue 3 · 23 Sep 2017 · 7,389 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleHost Cell and Antibody Response towards Pasteurella Multocida B2 Infection-A General ReviewEric Lim Teik Chung, Faez Firdaus Jesse Abdullah, Yusuf Abba et al.Pasteurella multocida was first shown to be the causative agent of fowl cholera by Louis Pasteur in 1881. Since then, this Gram-negative bacterium has been identified as the causative agent of many other economically important diseases in a wide range of hosts. Haemorrhagic Septicaemia (HS) is a disease, caused by Pasteurella multocida serotypes B2 and E2 that causes acute, highly … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 3 · 27 Jun 2015 · 7,857 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePRODUCTION AND CHARACTERIZATION OF MONOCLONAL AND POLYCLONAL ANTIBODY AGAINST RECOMBINANT OUTER MEMBRANE PROTEINMahdi Fasihi-Ramandi, Amir Nedjad-Moghaddam, Fatemeh Arabsalmany et al.There are many studies related to immunological and molecular methods for diagnosis of Vibrio cholera (V. cholerae). However, most assays dependent on enrichment of culture of bacteria, which need more time and involves the use of costly equipment and reagents. In this study Balb/c mice were immunized with recombinant Outer Membrane Protein (rOMPw) of vibrio cholerae and splenocytes of hyper … …American Journal of Immunology, Vol. 10, Issue 1 · 26 Apr 2014 · 7,439 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMonoclonal Antibody-Based Therapeutics for Melioidosis and GlandersHyung-Yong Kim, Alexander Stojadinovic, Peter J. Weina et al.Problem statement: Burkholderia Pseudomallei (BP) and B. Mallei (BM) were two closely related pathogenic gram-negative bacteria. They were the causative agents of melioidosis and glanders, respectively and are recognized by CDC as category B select agents. Significant efforts had been devoted to developing the diagnostic and therapeutic measures against these two pathogens. Monoclonal antibody-based therapeutic was a promising targeted therapy … …American Journal of Immunology, Vol. 7, Issue 3 · 23 Dec 2011 · 8,975 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAnti-Cardiolipin Antibody in Acute Myocardial InfarctionAbdolreza Sotoodeh Jahromi, Mohammad Shojaie, Samira Dana, Abdoulhossain MadaniProblem statement: Myocardial infarction is the combined result of environmental and personal factors. Data concerning the relation between anti-Phospholipid (aPL) antibodies and myocardial infarction in subjects without evidence of overt autoimmune disease are conflicting. Anticardiolipin antibody is detected in various diseases like rheumatoid arthritis, systemic lupus erythematosus and anti-phospholipid antibody syndrome. The study of Anticardiolipin antibody in Acute Myocardial Infarction … …American Journal of Immunology, Vol. 6, Issue 1 · 31 Mar 2010 · 7,827 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEpitope Mapping of Dengue-Virus-Enhancing Monoclonal-Antibody Using Phage Display Peptide LibraryChung-I Rai, Huan-Yao Lei, Yee-Shin Lin et al.The Antibody-Dependent Enhancement (ADE) hypothesis has been proposed to explain why more severe manifestations of Dengue Hemorrhagic Fever and Dengue Shock Syndrome (DHF/DSS) occur predominantly during secondary infections of Dengue Virus (DV) with different serotypes. However, the epitopes recognized by these enhancing antibodies are unclear. Recently, antipre-M monoclonal antibody (mAb 70-21), which recognized all DV serotypes without neutralizing activity, were … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 8,453 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAnti-Prm Antibody as an Autoantibody in Dengue Virus InfectionKao-Jean Huang, Yu-Tien Cheng, Yee-Shin Lin et al.We have reported that anti-prM antibody is an enhancing antibody that enhances DV infection of non-Fc receptor bearing cells by dual specificity. We identified the epitope recognized by this anti-prM antibody, M3, which is located at the a.a.53-67of the prM protein nearby the prM/M cleavage junction and these anti-M3 antibodies could be detected in dengue patients sera. Surprisingly, this anti-prM … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,304 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleProtection against Lipopolysaccharide-induced Death by An Anti-Interleukin-6 Monoclonal AntibodyBailin Liang, Debra Gardner, Don Griswold, Xiao-yu R. SongSepticemia is frequently associated with serious complications and high mortality despite recent advances in treatment with antibacterial agents. Infectious organisms or their soluble products initiate septic shock through a complex cytokine cascade. Lipopolysaccharide (LPS) induced excessive production of inflammatory cytokines is regarded as a model of septic shock. Experiments of LPS-induced excessive cytokine production were conducted in Balb/c mice for … …American Journal of Immunology, Vol. 3, Issue 1 · 30 Jun 2007 · 6,856 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleLarge Scale Production and Characterization of Anti-Human IgG Monoclonal Antibody in Peritoneum of Balb/c MICEB. Baradaran, J. Majidi, Z. M. Hassan, J. AbdolalizadehMonoclonal antibodies are key reagents that are used in biomedical researches, diagnosis of immunodeficiency diseases such as IgG subclasses deficiency and treatment of diseases like infections and cancers. For large scale production of monoclonal antibody, hybridoma cells that produce monoclonal antibody against human IgG were injected into the peritoneum of the Balb/c mice which have previously been primed with 0.5 … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 4 · 31 Dec 2005 · 7,089 accessesView PDFCite