Sign inSubmit
Tips: “quotes” for a phrase · author:Lee · a DOI goes straight to its article

17 results for “alloxan”
Set a search alert
Research ArticleOpen accessEvery word in the titleImpact of Euphorbia helioscopia Extract Administration on Diabetes Induced by Alloxan in MiceDoha Mohammad Beltagy, Amira Mohammed Beltagy, Mohammad Ramadan et al.Diabetes describes metabolic disorder with hyperglycemia and neurotic changes. This work aimed to evaluate the protective effect of total ethanolic extract of Euphorbia helioscopia grown in Egypt against pancreas and brain injuries in diabetic mice induced by alloxan. This work was carried out on 60 mice divided into four groups. Control Group (G1) included healthy normal mice that did not … …OnLine Journal of Biological Sciences, Vol. 20, Issue 3 · 19 Oct 2020 · 6,406 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleProtective Effect of Galactomannan Extracted from Iraqi Lycium barbarum L. Fruits against Alloxan-Induced Diabetes in RatsAdnan J.M. Al-FartosyLycium barbarum L. (Solanaceae) is widely used in Iraqi Ayurvedic medicine for the treatment of diabetes mellitus. The present investigation was done to evaluate the effects of polysaccharide (galactomannan) from Lycium barbarum L. Fruits (GLBF) on serum blood glucose, serum lipid profile and lipid peroxidation and antioxidant defence system in liver and kidney of alloxan-induced diabetic rats. GLBF was found … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 2 · 15 Dec 2014 · 7,653 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffect of Alloxan-Diabetes on Gastrin-Releasing Peptide (GRP) Immunoreactivity in the Gastrointestinal Tract, of Sprague Dawley Rats and How This May Affect Some of the Diabetic ComplicationsEdward O. Uche-Nwachi, Camille V. MitchellGastrin-releasing peptide (GRP) is the mammalian analogue of bombesin. Both neuroendocrine peptides have similar distribution, functions and immunoreactivity. The immunoreactivity for GRP has been demonstrated in the esophagus, stomach and small intestine. This peptide is reported to have various biological and pharmacological properties, which include the release of gastrointestinal hormones, control of satiety, gastrointestinal motility and stimulation of cellular proliferation … …OnLine Journal of Biological Sciences, Vol. 7, Issue 1 · 31 Dec 2007 · 7,250 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleHypoglycemic and Antihyperlipidemic Effect of Four Korean Medicinal Plants in Alloxan Induced Diabetic RatsJi Su Kim, Jung Bong Ju, Chang Won Choi, Sei Chang KimTo consider potentially new hypoglycemic and antihyperlipidemic sources, aqueous extracts from four Korean medicinal plants, Chrysanthemum coronarium, Dioscorea batatas, Morus alba, Citrus unshiu, were investigated in alloxan-induced diabetic rats. To induce diabetes, 36 rats were administered alloxan orally (120 mg/kg body weight) for 2 weeks and among those 6 rats were used as a diabetic control. Effect of extracts from … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 4 · 31 Dec 2006 · 9,166 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffects of Administration of Alpha-Melanocyte Stimulating Hormone (α-MSH) on Some Hematological Values of Alloxan-induced Diabetic RatsKamal M.S. MansiThis study was designed to evaluate the role of alpha- melanocyte stimulating hormone (α-MSH) on heart rate and some hematological values in alloxan induced diabetic rats. 40 male white rats were divided into four experimental groups: control, diabetic, α-MSH-treated and α-MSH-treated diabetic. At the end of the experimental period (3weeks), animals in all four groups were fasted for 12 hrs … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 1 · 31 Mar 2006 · 7,366 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAssessment of the Annona muricata Leaf Ethanol Extract Effect on The Diameter of Pancreatic Islets in Alloxan-Induced MiceSyafira N. Dewi, Supri I. Handayani, Marini Stephanie et al.Diabetes mellitus is one of a non-communicable disease whose prevalence continues to increase from year to year in both developed and developing countries. In Indonesia, it is estimated that 12 million people aged ≥15 years old had diabetes mellitus in 2013. Treatment of diabetes mellitus by using plant extract has been reported to have good results. One of the plants … …OnLine Journal of Biological Sciences, Vol. 20, Issue 1 · 9 Mar 2020 · 8,061 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAnti-Diabetic Activity of a Fraction from Cissus verticillata and Tyramine, its Main Bioactive Constituent, in Alloxan-Induced Diabetic RatsCleide de Sousa Lino, Thiago de P. Sales, Patrícia B. Gomes et al.Cissus verticillata (syn. C. sycioides, fam. Vitaceae) is a medicinal plant popularly used in Brazil, for the treatment of diabetes mellitus. The anti-diabetic activity of a fraction from leaves of Cissus verticilllata (MSF, methanol soluble fraction), as well as that of tyramine (TYR) were investigated, in the model of alloxan-induced diabetes, in male Wistar rats. The biochemical parameters studied were: … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 4 · 31 Dec 2007 · 8,627 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAntidiabetic and Antioxidant Potential of Vernonia amygdalina Leaf Extract in Alloxan-Induced Sprague-Dawley RatsFatmawaty Yazid, Nina Bonita Hasanah, Rosmalena et al.The treatment of diabetes mellitus using drug medications have side effects such as weight gain, hypoglycemia, the risk of cardiovascular or all-cause mortality. These limitations have become one reason to use complementary therapy from plant extract, such as Vernonia amygdalina as an antidiabetes. This research aimed to investigate the effect of V. amygdalina leaf extracts as antidiabetic and antioxidant agents … …OnLine Journal of Biological Sciences, Vol. 20, Issue 4 · 23 Nov 2020 · 8,649 accessesView PDFCite
Research ArticleOpen accessIn the keywordsExploration of Antidiabetic and Hypolipidemic Activity of Roots of Croton ZambesicusPrakash Kumar, Rahul Kumar, Manoj Kumar Rastogi, Krishna MurtiThe aim of this study was to investigate the potential antidiabetic and hypolipidaemic effects of aqueous and ethanolic extracts of roots of Croton zambesicus in alloxan induced diabetic models to ascertain its pharmacological applicability. The roots of Croton zambesicus were collected, dried and extracted. The phytochemical screening as well as Median Lethal Dose determination (LD50) was done. The ethanolic extract … …American Journal of Pharmacology and Toxicology, Vol. 12, Issue 1 · 12 Jun 2017 · 7,851 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Effect of Citrullus colocynthis Pulp Extract on the Liver of Diabetic Rats a Light and Scanning Electron Microscopic StudyMohammad Khalil, Gamal Mohamed, Mohammad Dallak et al.Problem statement: The goal of the current investigation was to clarify the effects of Citrullus colocynthis pulp extract on the structure of the liver of diabetic rats at both light and scanning electron microscopic levels. Approach: Forty-eight adult male albino rats were equally allocated into four groups: Group1: control, Group 2: Citrullus colocynthis-treated, Group 3: diabetic rats and Group4: diabetic … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 3 · 30 Sep 2010 · 9,478 accessesView PDFCite