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199 articles for “acute”

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Research ArticleOpen accessEvery word in the titleEvaluation of Acute Oral Toxicity Induced by Tablets Based on Ethanolic Extract of Salvia dumetorum Leaves in Experimental RatsYana Levaya, Karakoz Badekova, Mussa Zholdasbayev, Gayane AtazhanovaThe aim of this study was to assess the acute oral toxicity of a solid dosage form based on Salvia dumetorum Andrz. ex Besser leaf extract (SDT5) in experimental rats. Acute toxicity was evaluated over a 14-day observation period following a single oral administration at three dose levels (500 mg/kg, 1000 mg/kg, and 2000 mg/kg), prepared in 0.5 mL of … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 23 Jun 2026 · 1,241 accessesView PDFCite
Case ReportOpen accessEvery word in the titleAlcohol-Induced Rhabdomyolysis Complicated by Hyponatremia and Acute Kidney Injury Following Minor Trauma: A Case ReportVinay Tulsian, Drupad Das, M Sukumar, Prasan Kumar PandaRhabdomyolysis from alcohol is established, but combined binge intake, minor trauma, and vomiting-induced hyponatremia is a complex clinical scenario. Case study: This case report describes a young male with a three-year history of alcohol consumption who presented with rhabdomyolysis following binge drinking and a mild traumatic fall. He experienced 10 to 15 episodes of vomiting post-alcohol intake, subsequently developing anasarca. … …American Journal of Pharmacology and Toxicology, Vol. 20, Issue 1 · 23 May 2026 · 1,700 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEvaluation of the Renoprotective Effects of Valsartan in Methotrexate-Induced Acute Kidney Injury in RatsDina KutbiMethotrexate (MTX) is a widely used chemotherapeutic agent known for its nephrotoxic effects, which can lead to acute kidney injury in hospitalized patients. However, the mechanism by which MTX induces nephrotoxicity is not entirely clear, but it is believed to involve oxidative stress and direct toxic effects on renal tubules. Valsartan, an angiotensin II receptor blocker, has been shown to … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 4 May 2024 · 4,571 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleUse of Novel Triphenyltin (IV) Dithiocarbamate Compounds in Assessing the Cytotoxicity and Mode of Cell Death of Acute Lymphoblastic Leukemia Cell Lines, CCRF CEM (CCL-119)Normah Awang, Nur Hidayah Hasrin, Nurul Farahana Kamaludin et al.Chemotherapy and radiotherapy are often used to treat Acute Lymphoblastic Leukemia (ALL). However, the resistance problem of treatment using the current drug in ALL patients has decreased the effectiveness of such therapy. Therefore, a study needs to be conducted to identify the potential of new anticancer agents. Organotin (IV) dithiocarbamate, an organometallic compound, causes toxic effects on cancer cells in … …OnLine Journal of Biological Sciences, Vol. 23, Issue 2 · 10 Mar 2023 · 5,159 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffect of Essential Oils Versus Home Remedies on Relieving Signs of Acute Respiratory Tract Infection among ChildrenAbeer Abd El-Aziz Mohamed Madian, Mohammad Mahmoud Abd-Alhaseeb, Ebtsam Salah Yonis Mahrous, Rodaina Ahmed MokbelAcute Respiratory Infection (ARI) accounts for more than 94 million cases annually and 1.9 million deaths among children worldwide. ARI is the most common cause of illness and mortality in children under five years old. The purpose of this study was to investigate the effect of essential oils versus home remedies on relieving signs and symptoms of ARI among children. … …American Journal of Infectious Diseases, Vol. 17, Issue 1 · 27 Feb 2021 · 7,357 accessesView PDFCite
Case ReportOpen accessEvery word in the titleAn Unusual Case of Acute Abdomen: Intestinal Ascariasis: Case Report and Literature ReviewAshaur Azhar, Rebecca Ann LillisAscariasis is uncommon in United States of America but can be seen in immigrants and travelers. It can present with intestinal complications. We present a case of acute suppurative appendicitis with bowel perforation. Interestingly and unexpected, worms were palpated in the intestine in the operating room. Later, an adult Ascaris worm was identified in nasogastric tube canister. During hospitalization, a … …American Journal of Infectious Diseases, Vol. 15, Issue 4 · 14 Nov 2019 · 6,961 accessesView PDFCite
InvestigationOpen accessEvery word in the titleRegularities of the Oxidative Stress Processes in Case of Bleedings from Acute and Chronic Ulcers of the Stomach and DuodenumEkaterina Vladimirovna Silina, Mukimdjon Ahmadzhonovich Sobirovz, Sergey Brankovich Bolevich, Victor Aleksandrovich StupinThe main aim of the study was to determine ways of improving the results of treating patients with ulcer bleeding of various nature and severity. It was provided by the system study of free radical processes and evaluation of the effectiveness of timely antioxidant therapy. Material and methods. The study included 153 patients aged 18-94 years with acute and chronic … …OnLine Journal of Biological Sciences, Vol. 18, Issue 2 · 4 May 2018 · 7,416 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePathologies of Acute Interstitial Pneumonia in Feedlot CattleJose A. Valles, Michael D. Apley, Chris D. Reinhardt et al.Acute Interstitial Pneumonia (AIP) is a costly issue that affects feedlot cattle. Research has yet to elucidate the etiology of AIP; therefore a case-control study was conducted to evaluate possible management and physiological factors that contribute to AIP in feedlot cattle. The experiment was conducted during the summer of 2011 in a commercial feedyard in Kansas. Animals exhibiting clinical signs … …American Journal of Animal and Veterinary Sciences, Vol. 11, Issue 1 · 30 Mar 2016 · 7,896 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleImpact of Acute Bronchiolitis on Cardiac Functions and Serum microRNA-122 and 499Mona Abd El-Gelel Mohamed, Khalid Mahmoud ZayedBronchiolitis is an acute inflammatory injury of the bronchioles that is usually caused by a viral infection, most commonly Respiratory Syncytial Virus (RSV). This study aimed to verify the direct injurious effect of acute bronchiolitis on the myocardium and serum level of microRNA-122 and 499 (miR-122 and miR-499) of infected infants. Serum lactate dehydrogenase (LDH), creatine phosphokinase-isoenzyme MB (CK-MB) and … …American Journal of Infectious Diseases, Vol. 12, Issue 1 · 26 Jan 2016 · 7,250 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleFactors Those Up Regulate Klotho and Glutathione Peroxidase-1 Gene Expression Improve Renal Function in Rats with Acute Renal FailureFatma E. El-Gendey, Shabaan A. Hemeda, Gamal A. Sosa, Naglaa F. AlhusseiniAcute Renal Failure (ARF) has traditionally been defined as the abrupt and progressive loss of kidney functions resulting in the retention of urea and other nitrogenous waste products associated with interstitial inflammation, tubular injury and increasing Tumor Necrosis Factor (TNF). Mortality in patients with ARF remains high >50% in severely ill patients. Klotho gene is a new anti-aging gene. Genetic … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 3 · 15 Aug 2015 · 7,097 accessesView PDFCite