8 articles for “acid goal”

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EditorialOpen accessIn the abstractIs Rerum® the New Coley's Vaccine?Marco RuggieroColey's Vaccine and Cancer Immunotherapy Dr. William B. Coley is credited for having been the first to translate the observation of an association between bacterial infections, high fever and cancer remission into a successful cancer treatment. However, it is worth noting that such an association dates back to at least one century before Coley's times; as Wiemann and Starnes from … …American Journal of Immunology, Vol. 13, Issue 2 · 31 May 2017 · 12,285 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAMINO ACID TRANSPORTERS IN DRUG DISCOVERYMariafrancesca Scalise, Lorena Pochini, Michele Galluccio, Cesare IndiveriAdministered drugs interact with membrane transporters of epithelia, Blood Brain Barrier and other districts influencing their delivery and efficacy. Drugs can also be used as inhibitors of transporters involved in human pathology. Drug-transporter interactions are responsible of off-target effects contributing to toxicity. High Throughput Screening technologies increased the potential applications in therapy or in predicting side effects. These strategies will … …Current Research in Drug Discovery, Vol. 1, Issue 1 · 2 Oct 2014 · 7,101 accessesView PDF Cite

Research ArticleOpen accessIn the abstractReview Article; Duodeno-Gastro-Esophageal Reflux Combined and IsolatedAyman Osman Nasr, William Robb, Thomas Neil WalshBarrett’s esophagus is the chief risk factor for esophageal adenocarcinoma. Reflux of gastric acid has long been related to the development of esophagitis and Barrett’s esophagus, but the role of duodenal contents is controversial. We review the literature on the role of duodenal contents in the development of esophagitis, Barrett’s esophagus and adenocarcinoma in addition to the role of acid … …Current Research in Medicine, Vol. 4, Issue 1 · 8 May 2013 · 7,834 accessesView PDF Cite

Research ArticleOpen accessIn the abstractPart I: Removing of Zn(II) from Polluted Water: Determination of Precipitation Limit Of Zn(II) Ion With 2-Hydroxy-1,2,3-Propanetricarboxylic AcidFatmir Faiku, Haxhere Faiku, Arben Haziri et al.Problem statement: The goal of this research was to investigate the condition for removing of Zn cation from water, through precipitation method with 2-hydroxy-1,2,3-propanetricarboxylic acid as ligand. Approach: In this study we examined the precipitation of Zn(II) ion in water solutions of ZnSO4 × 7H2O (1×10-2 and 5×10-3 mol L-1) with 2-hydroxy-1,2,3-propanetricarboxylic acid (1×10-1-1×10-3 mol L-1) in constant ionic strength … …American Journal of Environmental Sciences, Vol. 6, Issue 1 · 28 Feb 2010 · 6,973 accessesView PDF Cite

Research ArticleOpen accessIn the abstractImportance of blood gas measurements in perinatal asphyxia and alternatives to restore the acid base balance status to improve the newborn performanceH. Orozco-Gregorio, D. Mota-Rojas, M. Alonso-Spilsbury et al.Prolonged or intermittent asphyxia in utero and during farrowing weakens piglets and renders them less capable of adaptation to extrauterine life. Piglets with lesser viability at birth have increased blood pCO2 and blood lactic acid concentrations and decreased blood pH. Moreover, the ability to thermoregulate during an acute cold stress is inversely related to umbilical blood lactate concentrations. Blood gas … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 3 · 30 Sep 2007 · 7,636 accessesView PDF Cite

Research ArticleOpen accessIn the abstractCPI-1189 Protects against TNBS-induced Colitis in a Rodent ModelBeverley Greenwood-Van Meerveld, Karl TylerNitrone-related therapeutics (NRTs) represents a new class of molecules that may be effective in treating inflammatory conditions. The goal of this study was to examine the effect of CPI-1189 in a rat model of inflammatory bowel disease (IBD). Colonic inflammation was induced by an enema of trinitrobenzene sulfonic acid (TNBS). Saline-enema treated rats served as controls. After 3 days colonic … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 2 · 30 Jun 2007 · 7,176 accessesView PDF Cite

EditorialOpen accessIn the abstractFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,865 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordPotential, Implications and Solutions Regarding the Use of Rendered Animal Fats in AquafeedsJesse T. Trushenski, Rebecca T. LochmannProblem statement: In the past, aquafeeds were comprised largely of fish meal and fish oil derived from marine reduction fisheries. In addition to being highly palatable and readily digested by cultured fishes, these feedstuffs were historically inexpensive sources of protein, energy and essential nutrients. However, increasing cost and concerns over safety and sustainability have greatly incentivized the transition from fish … …American Journal of Animal and Veterinary Sciences, Vol. 4, Issue 4 · 31 Dec 2009 · 14,003 accessesView PDF Cite