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239 results for “Z-drugs”
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Research ArticleOpen accessEvery word in the titleTheoretical Investigation of Two Antiemetic Drugs at DFT LevelKhalil Errahmane Kanouni, Yacine BenguerbaThe geometries and the bonding properties have been predicted for two antiemetic drugs using Density Functional Theory method (DFT). Mulliken population and frontier molecular orbital analysis with the determination of the physicochemical properties was performed using the Amsterdam Density Functional package (ADF). To calculate the exchange-correlation energy, the Generalized Gradient Approximation of Becke-Perdew (GGA-BP) was used. The most important finding … …Current Research in Bioinformatics, Vol. 9, Issue 1 · 14 May 2020 · 11,496 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDirect Acting Anti-Viral Drugs Improve Health-Related Quality of Life in Patients' with Hepatitis CWesam Morad, Warda Othman, Esam Elshimi, Nashwa SheblChronic hepatitis C Virus (HCV) causes significant decline in the Health Related Quality of Life (HRQL). Recently, direct Acting Anti-viral Drugs (DAA) have been endorsed as standard of care for treatment for HCV. To study the HRQL in patients with HCV and cirrhosis before and after DAA. Study design: Prospective cohort hospital based study. We included 500 patients with HCV … …American Journal of Infectious Diseases, Vol. 16, Issue 2 · 29 Apr 2020 · 7,145 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Extent of Community Awareness Using Natural Element’s Instead of Using Chemical DrugsMeliz Yuvalı, Ismail Bakır, Ilker EtikanAlternative medicine it is a medicine that is not taught in traditional medicine. It is based on ancient historical foundations and different experiments in treatment without building it on the basis of scientific teacher. Alternative medicine is used in many peoples, especially non-developed peoples. Alternative medicine is used as primary medicine. The evidence of poor quality and knowledge about the … …Current Research in Biostatistics, Vol. 7, Issue 2 · 25 Oct 2017 · 8,033 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleNon-Steroidal Anti-Inflammatory Drugs in Food Producing AnimalsDe Vito VirginiaProviding adequate food supply to meet the demands of a growing population is a challenge for this century. The food producing animals bred in optimized conditions supply a large amount of food derivatives. At the same time, society has become progressively more concerned about animal suffering and aware of the need of pain prevention and treatments. One of the measures … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 2 · 12 Jun 2015 · 7,715 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePrescription Pattern of Anti-Hypertensive Drugs in Adherence to JNC- 7 GuidelinesKrishna Murti, M. Arif Khan, Akalanka Dey et al.The main objective of the present study to investigate the utilization pattern of antihypertensive drugs in hypertensive patients and to find out whether the prescription pattern is in adherence with the JNC7 guidelines for the management of hypertension. A prospective study was conducted and drug utilization data were collected from 137 hypertensive patients who were attended as Out Patient Department … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 1 · 2 Jun 2015 · 8,273 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleWhat Is The “Safest” Non-Steroidal Anti-Inflammatory Drugs?Patompong Ungprasert, Wonngarm Kittanamongkolchai, Chrystal Price et al.Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) which are widely used in clinical practice are also very well-known for their various adverse reactions. Each NSAID has its own unique safety profile and selecting an appropriate NSAID must be individualized for each patient based on his or her medical needs and risk factors. We reviewed literatures on NSAIDs, focusing on their adverse reaction profile. … …Current Research in Medicine, Vol. 3, Issue 2 · 18 Jun 2012 · 16,261 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleStudy on Survival of Chlamydia trachomatis in the Presence of Antichlamydial DrugsApurb Rashmi Bhengraj, Pragya Srivastava, Harsh Vardhan et al.Problem statement: Recurrent genital Chlamydia trachomatis infections due to treatment failures may results in complex sequelae leading to reproductive complexity and morbidity. It can be resulted by the heterotypic resistance with decreased drug susceptibility characteristic of the isolate. Studies are needed to understand the treatment failures and resistance characteristic of C. trachomatis. Hence, in vitro study was conducted on C. … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 20 Feb 2012 · 7,768 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSlow Fungal Hydrolysis of Complex Sugar is Responsible for the Use of Sugar as Vehicle for Antifungal DrugsNedosa Ikenna Valentine, Utoh-Nedosa Uchechukwu Anastasia, Dan Danjuma et al.Problem statement: Aspergillus niger strain (UUF 9202) significantly reduced the dormancy period and boosted aggregate germination time in seeds of Tetrapleura tetraptera by 42% in 32 days and produced a net reduction in mean germination time of the seeds to 12 days. A structure-fungitoxicity relationship study of a series of isoflavonoids against Aspergillus niger and Cladosporium cucumerinum showed that a … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 3 · 2 Nov 2011 · 7,665 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleObservations on the Relationship between Opioid Medications, Illicit Drugs and Heroin Use in Pain PatientsDavid AlanYee, Michelle Marie Hughes, Rabia Samady Atayee et al.Problem statement: Patients on chronic opioid therapy are monitored to detect illicit drug use in order to deter diversion of their prescription opioids and to ensure medication adherence. The addictive potential of opioid drugs and their similar binding sites in the brain may make them potential gateway drugs for each other. Recent reports indicate that oxycodone has a high probability … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 1 · 7 Jun 2011 · 7,957 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleOptic Neuropathy: Characteristic Pathology for Identifying Drugs with Potential to Cause Mitochondrial ToxicityConnor Dyer, Katlyn Droke, Ugne Zekonyte, Mariana RoscaDeleterious effects on mitochondria are known to be frequently caused by prescription drugs, however, there is no standard and specific testing by pharmaceutical companies on these effects on mitochondria during drug development. The objective of this study is to determine if cases of optic neuropathy are related to drug-induced mitochondrial toxicity in a way that could be used to predict … …American Journal of Pharmacology and Toxicology, Vol. 18, Issue 1 · 19 Jan 2024 · 8,562 accessesView PDFCite