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13 articles for “Yao Chen”
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Research ArticleOpen accessIn the author namesOptimization of the Fermentation Medium of Streptomyces ahygroscopicus ΔnysB, a Tetramycin Producing Strain, by the Response Surface MethodXiao Wang, Yao Dong, Xin Chen et al.Streptomyces ahygroscopicus ΔnysB is a genetically engineered strain that produces tetramycin by blocking the competition nystatin pathway. Response Surface Methodology (RSM) was used to optimize its fermentation medium composition. Taking the yield of tetramycin as the response value, the effects of corn starch, glucose, fish peptone, (NH4)2SO4, KH2PO4, and CH3COONa on the yield of tetramycin were investigated by the Plackett-Burman … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 1 · 9 Apr 2024 · 5,327 accessesView PDFCite
Research ArticleOpen accessIn the author namesPreparation of Low-Sugar Herbal Buccal Tablet and its Antioxidant ActivityYuqing Wang, Mingjie Sun, Rui Xu et al.In this study, in order to prepare a low-sugar Herbal Buccal Tablet (HBT), Response Surface Methodology (RSM) was used to optimize the formula of HBT. HBT was prepared by wet granulation and tableting process on the basis of formula optimization. The in vitro antioxidant activity, glycemic index and particle microstructure of HBT were evaluated. The results showed that the optimal … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 1 · 8 Mar 2022 · 6,362 accessesView PDFCite
Research ArticleOpen accessIn the author namesC-Terminal Region of Dengue Virus Nonstructural Protein 1 Is Involved in Endothelial Cell Cross-Reactivity via Molecular MimicryShu-Wen Wan, Chiou-Feng Lin, Mei-Chun Chen et al.Infection with dengue virus (DV) causes diseases ranging from self-limited dengue fever to life-threatening dengue hemorrhagic fever and dengue shock syndrome. Vascular leakage, thrombocytopenia and bleeding are the clinical manifestations associated with dengue hemorrhage. We previously showed that anti-DV nonstructural protein 1 (NS1) antibodies (Abs) cross-reacted with endothelial cells. The potential target proteins on endothelial cell surface recognized by anti-DV … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,564 accessesView PDFCite
Research ArticleOpen accessIn the author namesEpitope Mapping of Dengue-Virus-Enhancing Monoclonal-Antibody Using Phage Display Peptide LibraryChung-I Rai, Huan-Yao Lei, Yee-Shin Lin et al.The Antibody-Dependent Enhancement (ADE) hypothesis has been proposed to explain why more severe manifestations of Dengue Hemorrhagic Fever and Dengue Shock Syndrome (DHF/DSS) occur predominantly during secondary infections of Dengue Virus (DV) with different serotypes. However, the epitopes recognized by these enhancing antibodies are unclear. Recently, antipre-M monoclonal antibody (mAb 70-21), which recognized all DV serotypes without neutralizing activity, were … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 8,455 accessesView PDFCite
Research ArticleOpen accessIn the author namesAnti-Platelet and Anti-Endothelial Cell Autoantibodies in Vietnamese Infants and Children with Dengue Hemorrhagic FeverNguyen Thanh Hung, Nguyen Trong Lan, Yee-Shin Lin et al.Dengue hemorrhagic fever (DHF) is a serious public health problem. Increased vascular permeability and thrombocytopenia are the hallmarks of DHF. The mechanisms involved in DHF/Dengue shock syndrome (DSS) pathogenesis is not fully understood. This study gives evidence of the presence of antibodies which cross-reacted with platelets, and endothelial cells in the sera of Vietnamese infants and children with DHF/DSS. The … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,371 accessesView PDFCite
Research ArticleOpen accessIn the author namesSignaling Pathways Involved In Dengue-2 Virus Infection Induced RANTES OverexpressionYing-Ray Lee, Huan-Yao Lei, Shun-Hua Chen et al.Dengue viruses participate in liver inflammation by inducting the expression of various chemokines including Regulated on Activation Normal T-cell Expressed and Secreted (RANTES). However, the underlying signaling remains unknown. Here, we reveal that Ras, Raf-1 and three mitogen-activated protein kinases (MAPKs) p38, extracellular signal-regulated kinase (Erk), and c-jun-NH2-terminal kinase (JNK) can be activated or phosphorylated in dengue-2 virus infected hepatocyte … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,176 accessesView PDFCite
Research ArticleOpen accessIn the author namesDengue Virus Infection Induced NF-κB-dependent Macrophage Migration Inhibitory Factor ProductionLien-Cheng Chen, Huey-Wen Shyu, Huan-Yao Lei et al.Dengue virus (DV) infection can cause mild dengue fever or severe dengue hemorrhage fever and dengue shock syndrome. Macrophage migration inhibitory factor (MIF) is a cytokine that plays an important role in the modulation of inflammatory and immune responses and serum levels of MIF are correlated with disease severity in dengue patients. However, the mechanism that induces MIF production during … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,293 accessesView PDFCite
Research ArticleOpen accessIn the author namesCorrelation of IFN-Inducible Protein 10 Levels in Sera with Disease Severity and Clinical Outcome of the Dengue PatientsYing-Ray Lee, Nguyen-Thanh Hung, Ching-Chuan Liu et al.Dengue Virus (DV) infection may cause life-threatening Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS). Although many cytokines involved in the pathogenesis of DHF/DSS have been reported, the expression status of IFN-inducible protein-10 (IP-10) in dengue patients is still unknown. This is the first report to unravel that IP-10 level was significantly elevated in the sera of Dengue Fever … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,053 accessesView PDFCite
Research ArticleOpen accessIn the author namesResearch of an Online Service System for Beverages Chain StoresChih-Yao Lo, Cheng-I Hou, Hsin-Chia Hsu, Chiu-Ping YouProblem statement: In the highly competitive market, the availability of consumer support is the key to market-based beverage stores. Consumer demands for quality service so the industry must be more active to improve the quality of management to ensure that beverage market position. In order to allow market competition to be improved for the beverage store. Approach: The system builds … …American Journal of Applied Sciences, Vol. 8, Issue 7 · 24 Jun 2011 · 7,057 accessesView PDFCite
Research ArticleOpen accessIn the author namesAnti-Prm Antibody as an Autoantibody in Dengue Virus InfectionKao-Jean Huang, Yu-Tien Cheng, Yee-Shin Lin et al.We have reported that anti-prM antibody is an enhancing antibody that enhances DV infection of non-Fc receptor bearing cells by dual specificity. We identified the epitope recognized by this anti-prM antibody, M3, which is located at the a.a.53-67of the prM protein nearby the prM/M cleavage junction and these anti-M3 antibodies could be detected in dengue patients sera. Surprisingly, this anti-prM … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,308 accessesView PDFCite