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21 results for “Yan Wang”

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Research ArticleOpen accessIn the author namesEffects of Atorvastatin on Oxidized Low-Density Lipoprotein-induced Proliferation, Apoptosis, and Matrix Metalloproteinase-9 Expression in Human MacrophagesBensheng Liu, Huifan Li, Yan Wang, Li ZhangAtorvastatin (ATV), an HMG-CoA reductase inhibitor, is utilized in the treatment of atherosclerotic diseases. Mononuclear Macrophages (MMs) are critical immune cells involved in atherosclerosis progression, participating in processes such as foam cell formation, cytokine secretion, and the development of fibrous cap and lipid core. To further elucidate the mechanism by which ATV exerts its therapeutic effects on atherosclerosis through the … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 18 Nov 2025 · 2,133 accessesView PDFCite
Research ArticleOpen accessIn the author namesUPLC-Q-Exactive Orbitrap-MS Analysis of Anchusa italica Retz. Flowers: Molecular Docking, Dynamics Modeling, and Pharmacokinetics for Cardiovascular DiseaseLinyang Wang, Yan Chen, Ainiwaer Aikemu, Shuge TianThis study builds on prior UPLC-Q-Exactive Orbit rap-MS analyses of Anchusa italica Retz. Flowers (Airfs) to explore their anti-cardiovascular mechanis·ms and key bioactive markers. UPLC-Q-Exactive Orbitrap-MS identified 30 major compounds, including polyphenols and flavonoids with strong antioxidant activity. The potential active ingredients were then screened using Lipinski's rule of five, and a network pharmacology method was employed to construct an … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 25 Oct 2025 · 2,599 accessesView PDFCite
Research ArticleOpen accessIn the author namesAcer Buergerianumas a New Resource for the Extraction of Corilagin: Determination of Corilaginin Different Cultivars of A. Buergerianumby UPLCQian Qiao, Chong Wu, Jiangyong Wang et al.Corilagin is a promising anticancer drug candidate. Acer nikoense and A. ammonium are both known to contain corilagin. To explore whether corilagin occurs in congeneric species and to fully develop the medicinal value of maple, the corilagin content in different varieties of maple was determined by Ultrahigh-Performance Liquid Chromatography (UPLC). Acer buergerianum leaves contained corilagin and the corilagin content in … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 2 · 12 May 2022 · 5,704 accessesView PDFCite
Research ArticleOpen accessIn the author namesDistribution Pattern of SN in Qinghai-Tibet Plateau and Its Relationship with Environmental FactorsXibo Feng, Yan He, Yi Zhang et al.Studying the distribution pattern and driving mechanism of Soil Nitrogen (SN) in the agricultural areas of the Qinghai-Tibet Plateau is of certain significance for the rational use of N fertilizer, improving the quality of land use and protecting the environment. The SN content of cultivated soil in Qinghai-Tibet Plateau agricultural areas was analyzed by combining geographical and meteorological factors. It … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 3 · 2 Jul 2020 · 6,625 accessesView PDFCite
Research ArticleOpen accessIn the author namesEffects of Potassium Fulvic Acid and DA-6 on the Growth and Yield of Tomato Cultivated with Rock WoolXiao Huaijuan, Zhou Yan, Mao Ke et al.Potassium fulvic acid and diethyl aminoethyl hexanoate (DA-6) are two kinds of growth regulators with yield increasing and quality improving. There are few reports on the effects of adding potassium fulvic acid and DA-6 in nutrient solution on the growth of soilless culture of vegetables. In this study, tomato was used as the test material to add different concentrations of … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 7 Apr 2020 · 8,285 accessesView PDFCite
Research ArticleOpen accessIn the author namesExtraction, Partial Identification and Bioactivities of Total Flavonoids from Carex meyeriana KunthHongbiao Wang, Penghui Wang, Xiudong Yang et al.To date, knowledge associated with extraction, chemical constituents and bioactivities of Total Flavonoids from Carex meyeriana Kunth (TFCMK) that remains unclear. Therefore, this paper was designed to optimize the ethanol reflux extraction method by response surface methodology and determine the chemical constituents by Liquid Phase-Mass Spectrometry (HPLC-MS); additionally, the bioactivities including antioxidant, antibacterial and hemolysis test were also explored. The … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 3 · 7 Aug 2019 · 7,523 accessesView PDFCite
Review ArticleOpen accessIn the author namesThe Progress of BMP4 on the Role of Ocular Development and Eye DiseasesLiang Jiaming, Wang Qian, Liu Xiaohe et al.Bone morphogenetic protein belongs to the transforming growth factor beta superfamily, is a unique ectopic cartilage and bone inducing activity of acidic protein. As one of the members of BMPs family, the formation and development of BMP4 in many organizations. In ocular tissue, BMP4 not only promotes the differentiation and development of different eye cells, but also plays an important … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 2 · 5 Apr 2017 · 7,686 accessesView PDFCite
Research ArticleOpen accessIn the author namesBinding Mechanism of Bovine Serum Albumin to Troxerutin by Synchronous Fluorescence Spectroscopy and ChemometricsTianhu Wang, Yi Yan, Yinsheng LuoPrevious works have reported the binding of Bovine Serum Albumin (BSA) to troxerutin by absorption and fluorescence spectroscopy. In order to extend the investigation of their binding characteristics, the study presented here was designed to evaluate their interaction by the synchronous fluorescence spectroscopy and Multivariate Curve Resolution With Alternating Least Squares (MCR-ALS) under simulative physiological conditions. The Evolving Factor Analysis … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 2 · 14 May 2016 · 7,449 accessesView PDFCite
Review ArticleOpen accessIn the author namesReview of the Progress in Corneal Neovascularization Animal ModelsShuci Tian, Shurong Wang, Yuxi He et al.Corneal Neovascularization (CNV), the extensive growth of blood vessels from conjunctiva into the cornea. It is a sight-threatening condition that can decreases eyesight and even leads to blindness. The pathologic growth of blood vessels impairs light transmission, promotes scar formation and causes inflammations, which harm visual acuity. Abnormal angiogenesis plays an important role in the process of CNV, which may … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 4 · 28 Nov 2015 · 8,421 accessesView PDFCite