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3 results for “Umbilical Cord”

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Research ArticleOpen accessPhrase in the titlePassage Effect on Aging of Human Umbilical Cord Derived Mesenchymal Stem CellDian Mediana, Isabella Kurnia Liem, Jeanne Adiwinata Pawitan, Noviyanti GoeiTo be used in regenerative medicine, cells should be checked for various conditions, including cell aging. This study aimed to learn senescent profile and its relation to cell viability, proliferation and cell size in various passages, which were done in α-MEM-10% PRP medium, until senescence-associated β-galactosidase (SA-β-Gal) positive cells were found. Stem cells were isolated from umbilical cord tissue by … …OnLine Journal of Biological Sciences, Vol. 15, Issue 3 · 31 Jul 2015 · 8,039 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleEffect of Platelet Rich Plasma on Post Cryopreservation Viability, Morphology and Proliferation of Human Umbilical Cord Stem CellsNoviyanti Goei, Isabella Kurnia Liem, Jeanne Adiwinata Pawitan, Dian MedianaIn most cryopreservation medium, Fetal Bovine Serum (FBS) is used as supplement, while it is well known that FBS contains xenoproteins that can be incorporated into the cells and may be harmfull, as they can elicit immune response. Therefore, finding other xenofree materials as FBS alternative in cryopreservation medium is very important. Platelet Rich Plasma (PRP) is albumin rich and … …OnLine Journal of Biological Sciences, Vol. 15, Issue 2 · 4 Jun 2015 · 7,386 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleIntravenous Injection of Umbilical Cord-Derived Mesenchymal Stem Cells Improved Regeneration of Rat Liver after 2AAF/CCl4-Induced InjuryIsabella Kurnia Liem, Reni Oktavina, Zakiyah et al.The effectivity of Mesenchymal Stem Cell (MSC) therapy for chronic liver injury is still questioned due to its possibility to have a pro-fibrotic effects. Other consideration is the preferably peripheral Intravenous (IV) route of application rather than direct to the target organ, such as portal vein or splenic vein, since the most of MSC will be trapped in the lung … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 10 Jun 2021 · 6,780 accessesView PDFCite