6 results for “The Lewis Effect”

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Research ArticleOpen accessIn the keywordsOn Micromechanisms of Hydrogen Plastification and Embrittlement of Some Technological MaterialsYu. S. Nechaev, T. N. VezirogluSome fundamental problems of revealing micromechanisms of hydrogen plastification, superplasticity, embrittlement, cracking, blistering and delayed fracture of some technologically important industrial metallic materials are formulated. The ways are considered of these problems' solution and optimizing the technological processes and materials, particularly in the hydrogen and gas-petroleum industries, some aircraft, aerospace and automobile systems. …American Journal of Applied Sciences, Vol. 2, Issue 1 · 31 Jan 2005 · 6,864 accessesView PDF Cite

Research ArticleOpen accessIn the abstractSoret and Dufour Effects on Natural Convection Flow Past a Vertical Surface in a Porous Medium with Variable Surface TemperatureHassan A.M. El-ArabawyProblem statement: In this research the researchers studied and made an analysis to the heat and mass transfer characteristics of natural convection about a vertical surface embedded in a saturated porous medium with surface temperature distribution proportional to xλ by taking into account the diffusion-thermo (Dufour) and thermal-diffusion (Soret) effects. Approach: The governing partial differential equations were transformed into a … …Journal of Mathematics and Statistics, Vol. 5, Issue 3 · 30 Sep 2009 · 7,485 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordA Bayesian Method for Disentangling Dependent Structure of Epistatic InteractionJing Zhang, Qu Zhang, Darrin Lewis, Michael Q. ZhangProblem statement: We propose a Bayesian method (RBP) to recursively infer the independence structure of epistatic interactions in case-control study. Approach: Based on the results of BEAM2, RBP can powerfully detect the marginal and conditional independence within interacting SNPs even in the complicated interaction cases. Results: We did extensive simulations to test RBP and compare it with stepwise logistic regression. … …Current Research in Biostatistics, Vol. 2, Issue 1 · 13 Jan 2012 · 7,476 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordTacrolimus Dosing Challenges in an African American ChildTeresa V. Lewis, Tracy M. Hagemann, Martin A. TurmanIt has been suggested that African Americans have decreased effectiveness with immunosuppressive drugs. Data regarding the pharmacokinetics of tacrolimus in African Americans are limited. We present the case of an African American child in whom management of nephrotic syndrome caused by focal segmental glomerulosclerosis has been challenging due to unpredictable patient specific pharmacokinetic disposition of tacrolimus. Racial differences have been … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 3 · 30 Sep 2007 · 6,708 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordRapamycin Inhibits Cystogenesis by Cystic Epithelial Cells Derived from Human Autosomal Dominant Polycystic KidneysGerard Elberg, Teresa V. Lewis, Lijuan Chen, Martin A. TurmanAutosomal dominant polycystic kidney disease (ADPKD) is one of the most common genetic disorders and carries a high health burden since it progresses to renal failure in half of the afflicted individuals by the 6th decade of life. Currently, there is no effective treatment to slow the progression of ADPKD. Rapamycin, a drug most commonly used as an immunosuppressive agent … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2006 · 7,101 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordPathophysiology of Adipocyte Defects and Dyslipidemia in HIV Lipodystrophy: New Evidence from Metabolic and Molecular StudiesAshok Balasubramanyam, Rajagopal V. Sekhar, Farook Jahoor et al.Despite a burgeoning mass of descriptive information regarding the epidemiology, clinical features, body composition changes, hormonal alterations and dyslipidemic patterns in patients with HIV lipodystrophy syndrome (HLS), the specific biochemical pathways that are dysregulated in the condition and the molecular mechanisms that lead to their dysfunction, remain relatively unexplored. In this paper, we review studies that detail the metabolic basis … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,608 accessesView PDF Cite