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55 results for “T lymphocytes”
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Research ArticleOpen accessEvery word in the titleAnalysis of Nucleoli in Intact Lymphocytes in Different Mammalian Species and HybridsBaylar Iolchiev, Pavel Klenovitskiy, Vugar Bagirov et al.The purpose of this study was to develop methods for quantitative and qualitative assessment of the activity of the nucleolus using the color intensity of argyrophilic regions and to study the effect of the species feature on the quantitative and qualitative indicators of the nucleoli and nucleolus organizer regions. The experiment involved Ovis aries (n = 40), hybrids of domestic … …OnLine Journal of Biological Sciences, Vol. 22, Issue 1 · 24 Jan 2022 · 6,069 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleInduction of Micronuclei in Mice Lymphocytes Exposed to Microwave and TolueneS. B. Mortazavi, A. Safari, A. Khavanin et al.Increasing applications of microwave radiation are of great concern with regard to public health. Several studies have been conducted detect effects of microwave exposure genetic material leading to negative or questionable results. The Micronucleus (MN) assay which is proved to be a useful method for detection of radiation exposure-induced cytogenetic damage was used in the present study to investigate the … …American Journal of Applied Sciences, Vol. 2, Issue 9 · 30 Sep 2005 · 6,614 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAccumulation of Cholesterol Esters in ex vivo Lymphocytes from Scrapie-susceptible Sheep and in Scrapie-infected Mouse Neuroblastoma Cell LinesAlessandra Pani, Claudia Norfo, Claudia Abete et al.Our studies on the role of cholesterol homeostasis in the pathogenesis of scrapie in sheep, revealed abnormal accumulation of cholesterol esters in brains and in ex vivo skin fibroblasts from genetically scrapie-susceptible, as compared to sheep with resistant genotype. We now report that PBMCs isolated from scrapie-susceptible sheep, as well as mouse neuroblastoma cell lines persistently infected with two different … …American Journal of Infectious Diseases, Vol. 3, Issue 3 · 30 Sep 2007 · 6,955 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPreliminary Study on Immunomodulatory Effect of Sarang-Semut Tubers Myrmecodia tuberosa and Myrmecodia pendensTriana Hertiani, Ediati Sasmito, Sumardi, Maria UlfahProblem Statement: Sarang-Semut tubers, Myrmecodia tuberosa and M. pendens (Rubiaceae) are both medicinal plants originating from Papua which have broad range of therapeutic values including those to improve vitality. Nevertheless, no scientific proof is available so far on their immunomodulatory effect. The purpose of this study was to reveal the potency of Sarang-Semut tubers as immunomodulatory agent by evaluating their … …OnLine Journal of Biological Sciences, Vol. 10, Issue 3 · 30 Sep 2010 · 13,397 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIn vitro Activation of Human and Rat Lymphocyte and Macrophage Functions by NorepinephrineRicardo Gomez-Flores, Diana Caballero-Hernandez, Richard J. Weber et al.Norepinephrine (NE) has been associated not only with increasing blood pressure, atherosclerosis, heart disease, and other life threatening conditions, but also with altering immune responses by influencing leukocyte functions. In the present study, we evaluated the in vitro effects of NE on rat thymic lymphocyte and human peripheral blood mononuclear cells (HPBMC) functions. We observed that NE marginally, but significantly … …American Journal of Immunology, Vol. 1, Issue 4 · 31 Dec 2005 · 7,075 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Tumor/Immune Interface: Clinical Evidence of Cancer Immunosurveillance, Immunoediting and ImmunosubversionMatthew S. Block, Svetomir N. MarkovicProblem statement: The interactions of a malignant tumor with the patient’s immune system are dynamic, multiple and bi-directional. Approach: This article reviews the clinical evidence of the interaction of cancer with immunity with emphasis on recent developments highlighting some of the mechanisms of tumor-mediated regulation of immunity. Results: Most of the time, the immune response to a malignancy acts to … …American Journal of Immunology, Vol. 5, Issue 1 · 31 Mar 2009 · 10,095 accessesView PDFCite
Research ArticleOpen accessIn the keywordsLoss of Morphine-induced Suppression of NK Cell activity and T-cell Functions in µ-Opioid Receptor Knockout MiceRichard J. Weber, Ricardo Gomez-Flores, Ichiro Sora, George R. UhlIn vivo administration of µ-opioid receptor selective agonists to various species is known to suppress lymphocyte, NK cell, and macrophage functions, in addition to mediate pain relief and euphoria. Using a mouse model in which the µ-opioid receptor gene was disrupted by targeted homologous recombination, we explored the involvement of this receptor in natural killer (NK) cell activity and T … …American Journal of Immunology, Vol. 2, Issue 2 · 30 Jun 2006 · 6,937 accessesView PDFCite
Research ArticleOpen accessIn the keywordsSelective Lymphocyte Activation and Inhibition of In Vitro Tumor Cell Growth by Novel MorphinansRicardo Gomez-Flores, Kimberly R. Vietti, William J. Dunn et al.Opioids can suppress immune functions and increase susceptibility to developing cancer and infectious diseases. Recently, novel opioid compounds have been synthesized that lack immunosuppressive effects. We evaluated the effects of morphinans with substituted pyrimidine (methyl, phenyl, hydroxy, and amino groups) and pyrazole groups on in vitro rat thymic lymphocyte and splenic macrophage functions, and tumor cell growth. We observed that … …American Journal of Immunology, Vol. 2, Issue 1 · 5 Mar 2005 · 7,078 accessesView PDFCite
Research ArticleOpen accessIn the abstractEnhanced Immunity of Hybrid Grouper (Epinephelus sp.) Against Viral Nervous Necrosis Using a Recombinant Protein Nanovaccine from Chlorella VulgarisUun Yanuhar, Herly Evanuarini, Heru Suryanto et al.Hybrid Grouper (Epinephelus sp.) is an important export commodity in marine aquaculture, yet Viral Nervous Necrosis (VNN) remains a major threat. Nanovaccines are a type of vaccine developed by combining vaccine ingredients with silver nanoparticles and recombinant protein from Chlorella vulgaris. These formulations are designed to effectively boost the body's immune system response to prevent disease infection and destroy pathogenic … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 22 Nov 2025 · 2,154 accessesView PDFCite
Case ReportOpen accessIn the abstractHistopathology of Microbially Induced Corrosion and Cluster Failure of Moderately Rough Surface Oral Implants in a Resident Bone MicrobiotaStephen Nelson, Helen Hu et al.This case report presents as a maxillary "cluster-failure", where six moderately rough-surface oral implants (1-2 microns) were installed to support a full-arch hybrid bridge. Understanding cluster failures requires the acknowledgment of biofilm science that recognizes the persistence of bacterial infection in bone following extraction and the need to bioremediate the bone-bed, by surgical debridement, before implant installation. The patient, a … …Current Research in Dentistry, Vol. 15, Issue 1 · 28 Feb 2024 · 8,482 accessesView PDFCite