6 results for “Synthetic Biology”

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Research ArticleOpen accessIn the keywordsOSCILLATORY SYNTHETIC BIOLOGICAL SYSTEM CONSTRUCTION USING INTERACTIVE EVOLUTIONARY COMPUTATIONSQuang Huy Dinh, Nasimul Noman, Hitoshi IbaIn this study, we propose an Interactive Evolutionary Computation system to design gene networks for synthetic biology, of which the objective is to construct new organisms through the artificial synthesis of gene networks. Wet laboratories typically design gene networks through trial and error methods, which makes the construction of complex networks difficult. As a solution, automation can significantly improve the … …Journal of Computer Science, Vol. 10, Issue 12 · 14 Jan 2015 · 8,476 accessesView PDF Cite

Review ArticleOpen accessIn the abstractAdvances in Modern Biotechnological Tools for Sustainable Control of Plant Viral DiseasesNabela Akter, Ankita Saha, Md. Abdullah Al Sabbir, Md. Motaher HossainPlant viruses pose a major threat to global food production, causing yield losses across many staple and horticultural crops. Conventional breeding for resistance is typically slow and constrained by the number of available natural resistance genes. Recent breakthroughs in biotechnology have enabled the development of accurate, flexible, and environmentally friendly technologies to confer virus resistance. This review summarizes exciting developments … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 16 Jul 2026 · 726 accessesView PDF Cite

EditorialOpen accessIn the abstractFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,862 accessesView PDF Cite

EditorialOpen accessIn the abstractRe-Paving the Road Built by Chemistry: A Challenge to Biochemistry and BiotechnologyAlberto A. IglesiasBiochemistry’s birth can be placed at the end of the nineteenth century, when Eduard Buchner made a clever interpretation of experimental observations on the generation of gas bubbles after addition (the original purpose was preservation) of sucrose to a yeast crude extract (Lagerkvist, 2005). Intelligently, Buchner concluded that the disaccharide had been fermented by broken cells’ suspension to produce CO2, … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 1 · 26 Jan 2015 · 7,461 accessesView PDF Cite

Research ArticleOpen accessIn the abstractGenetic Algorithm Based Probabilistic Motif Discovery in Unaligned Biological SequencesM. Hemalatha, K. VivekanandanFinding motif in biosequences is the most important primitive operation in computational biology. There are many computational requirements for a motif discovery algorithm such as computer memory space requirement and computational complexity. To overcome the complexity of motif discovery, we propose an alternative solution integrating genetic algorithm and Fuzzy Art machine learning approaches for eliminating multiple sequence alignment process. Problem … …Journal of Computer Science, Vol. 4, Issue 8 · 31 Aug 2008 · 6,729 accessesView PDF Cite

Research ArticleOpen accessIn the abstractMicroarray Analysis of Human Vascular Smooth Muscle Cell Responses to Bacterial LipopolysaccharideJoe Minta James, J. Yun, Sandy Der, Shikha RanaAccumulating evidence suggest a causal role of bacterial and viral infections in atherogenesis. Bacterial lipopolysaccharide (LPS) has been shown to stimulate resting vascular smooth muscle cells (SMC) with the production of inflammatory cytokines and modulation of quiescent cells to the proliferative and synthetic phenotype. To comprehensively identify biologically important genes associated with LPS-induced SMC phenotype modulation, we compared the transcriptomes … …American Journal of Immunology, Vol. 3, Issue 2 · 31 Dec 2007 · 6,994 accessesView PDF Cite