Review ArticleOpen accessIn the abstractAstrocytes Store for Memory and CognitionMajid Karimi BaghmalekiIn humans, protoplasmic astrocytes are found with high density in the cortex and hippocampus (both parts responsible for memory and cognition) and each astrocyte is in contact with two million of synapses. Astrocytes are responsible for the synaptogenesis and the removal of synapses, which is the basis of learning and memory. The synaptogenesis increases sevenfold with the addition of astrocytes … …Neuroscience International, Vol. 12, Issue 1 · 21 Apr 2021 · 17,209 accessesView PDFCite
HypothesisOpen accessIn the abstractIncreased Tissue Pressure Induces Demyelinated Lesions and Necroses in the BrainHelmut Barz, Ulrich Barz, Almut SchreiberA general brain edema increases the size of the brain tissue and stretches the elastic neuronal and glial fibers. Myelinated fibers are more elastic than unmyelinated fibers. The stretching of the neuronal fibers leads particular in regions of the white matter or areas surrounded by myelinated fiber tracts to an increased tissue pressure. This physical principle can be the reason … …Neuroscience International, Vol. 6, Issue 1 · 30 Mar 2015 · 7,424 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmune-Based Therapies for Spinal Cord InjuryBasem I. Awad, Davina V. Gutierrez, Michael P. SteinmetzTraumatic Spinal Cord Injury (SCI) results in both focal and diffuse spinal cord pathologies that are exacerbated by an inflammatory response after the initial injury. Resident and infiltrating immune cells contribute significantly to the growth-refractory environment near the lesion and can intensify damage to spared tissue, resulting in impaired spontaneous functional recovery. Numerous studies have demonstrated that several immunomodulatory therapies … …Neuroscience International, Vol. 4, Issue 1 · 17 Apr 2013 · 6,877 accessesView PDFCite