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11 results for “Spinal Cord”
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Research ArticleOpen accessPhrase in the titleImmune-Based Therapies for Spinal Cord InjuryBasem I. Awad, Davina V. Gutierrez, Michael P. SteinmetzTraumatic Spinal Cord Injury (SCI) results in both focal and diffuse spinal cord pathologies that are exacerbated by an inflammatory response after the initial injury. Resident and infiltrating immune cells contribute significantly to the growth-refractory environment near the lesion and can intensify damage to spared tissue, resulting in impaired spontaneous functional recovery. Numerous studies have demonstrated that several immunomodulatory therapies … …Neuroscience International, Vol. 4, Issue 1 · 17 Apr 2013 · 6,877 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleSpinal Cord Injury: Current Mammalian ModelsSarina Kundi, Roy Bicknell, Zubair AhmedIt is estimated that approximately 2.5 million people are affected by Spinal Cord Injury (SCI), with more than 130,000 new cases reported each year (International Campaign for Cures of Spinal Cord Injury Paralysis). Although there is currently no cure for SCI, various strategies including rehabilitative, cellular and molecular therapies have been tested in a variety of animal models. But questions … …Neuroscience International, Vol. 4, Issue 1 · 27 Mar 2013 · 14,041 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleEffects of Body Weight-Support Treadmill Training in Incomplete Spinal Cord Injury: A Critical ReviewRenata Teles Vieira, Rafaela Machado de Gusmao Oliveira, Camila Alves Nogueira Barros et al.Problem statement: The present study reviewed the efficacy of body-weight support treadmill training in patients with incomplete spinal cord injury. Approach: We developed a computer-supported search strategy for finding studies in the main data bases: Pubmed/Medline, ISI Web of Knowledge and Scielo. We also developed a manual search withing all electronically references found. The search terms gait, locomotor training, spinal … …Current Research in Medicine, Vol. 3, Issue 2 · 23 Aug 2012 · 7,729 accessesView PDFCite
Research ArticleOpen accessIn the keywordsSpatial Distribution of Fibroblast Growth Factor Receptor 2 in Normal and Lesioned Central Nervous System of Pleurodeles waltliiMarie Moftah, Marc Landry, Frederic Nagy, Jean-Marie CabelguenFibroblast Growth Factors (FGFs) have been implicated in numerous cellular processes including proliferation, migration, differentiation and neuronal survival. One of these growth factors, Fibroblast Growth Factor 2 (FGF2), is apparently implicated in the ability of the adult salamander (Pleurodeles waltlii) to recover locomotion following complete transection of the spinal cord. In a previous study, we reported up regulation of FGF2 … …Neuroscience International, Vol. 3, Issue 2 · 4 Sep 2012 · 7,145 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of the Role of Galanin Hormone and Biochemical Markers in Individuals with Hair LossSheerin Farouq Shaker, Sarab Dalaf Khalaf, Omeed Akbar Ali, Shaimaa Tariq MahmoodHair loss is one of the problems that many people suffer from without knowing the real reason. Galanin is a neuropeptide closely involved in the modulation and inhibition of action potentials in neurons in the brain, spinal cord, and gut of humans. Therefore, we believe that it has a role in mineral absorption and hair loss. The aim of this … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 30 Jan 2026 · 1,928 accessesView PDFCite
Review ArticleOpen accessIn the abstractAstrocytes Store for Memory and CognitionMajid Karimi BaghmalekiIn humans, protoplasmic astrocytes are found with high density in the cortex and hippocampus (both parts responsible for memory and cognition) and each astrocyte is in contact with two million of synapses. Astrocytes are responsible for the synaptogenesis and the removal of synapses, which is the basis of learning and memory. The synaptogenesis increases sevenfold with the addition of astrocytes … …Neuroscience International, Vol. 12, Issue 1 · 21 Apr 2021 · 17,209 accessesView PDFCite
Research ArticleOpen accessIn the abstractEtiology of Meningitis from Patients Suspected of Meningitis Attending Tribhuvan University Teaching Hospital, Kathmandu, NepalPinky Pandey, Bharat Jha, Anima ShresthaMeningitis is an inflammatory infection of the membranes surrounding the brain and spinal cord, which occurs either as a primary disease or secondarily to disease in some other parts of the body. Its most frequent causes are Neisseria meningitidis, Streptococcus pneumoniae and Haemophilus influenzae. The epidemiological trend of acute meningitis varies with time and geography. Information on the relative frequency … …Current Research in Microbiology, Vol. 6, Issue 2 · 14 Jul 2015 · 9,143 accessesView PDFCite
HypothesisOpen accessIn the abstractIncreased Tissue Pressure Induces Demyelinated Lesions and Necroses in the BrainHelmut Barz, Ulrich Barz, Almut SchreiberA general brain edema increases the size of the brain tissue and stretches the elastic neuronal and glial fibers. Myelinated fibers are more elastic than unmyelinated fibers. The stretching of the neuronal fibers leads particular in regions of the white matter or areas surrounded by myelinated fiber tracts to an increased tissue pressure. This physical principle can be the reason … …Neuroscience International, Vol. 6, Issue 1 · 30 Mar 2015 · 7,424 accessesView PDFCite
EditorialOpen accessIn the abstractAMYOTROPHIC LATERAL SCLEROSIS: HOW TO UNDERSTAND SUCH DIVERSE AND SO ENTANGLED PHYSIOPATHOLOGY?Carlos Henrique Melo Reis, Marco Orsini, Marco Antônio Araujo Leite et al.When in 1865, JeanMartin Charcotreported patients with progressive muscular atrophysuperimposedwith spasticity of inexorable evolution as result of combinedlesions of the anterior horn and lateral column of the spinal cord, hecertainly inaugurated an attempt on the comprehension of one of the mostcomplexes neurological clinical conditions, which until today persists withimmense voids on their comprehension, regardless of the enormous advancesachieved. Astime went … …Current Research in Medicine, Vol. 5, Issue 2 · 16 Feb 2015 · 7,149 accessesView PDFCite
Research ArticleOpen accessIn the abstractBlockade of Group I Metabotropic Glutamate Receptors (mGluRs) Activation Inhibits Nociception Following Descending Colon Distension in SheepBogdan F. Kania, Danuta Wrońska, Mikołaj A. GralakExpression of mGluRs of groups I and II was found in structures of CNS closely related with nociception: spinal cord superficial fields, responsible for pain filling or modulation of neurotransmission in the peripheral receptors. The present study examined contribution of mGluRs to the development and maintenance of changes in behavioral and clinical symptoms caused by visceral pain. Experiments were carried … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 24 Dec 2014 · 7,427 accessesView PDFCite