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7 results for “Snake Venom”

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Research ArticleOpen accessPhrase in the titleInfluence of a Low-Level Semiconductor Gallium Arsenate Laser in Experimental Envenomation Induced by Bothrops atrox Snake VenomElziliam Aranha De Sousa, José Adolfo Homobono Machado Bittencourt, Nayana Keyla Seabra De Oliveira et al.Bothrops atrox is responsible for the majority of snakebite accidents in Brazilian Amazon and its venom can cause prominent local tissue damage. Experimental groups consisted of five male mice, each administered either B. atrox Venom (VB), B. atrox Venom + Antivenom (VAV), B. atrox Venom + Laser (VL), B. atrox Venom + Antivenom + Laser (VAVL), or Sterile Saline Solution … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 4 · 29 Dec 2012 · 7,500 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleIn Silico Characterization and Motif Election of Neurotoxins from Snake VenomMahmudul Hasan, Ziaul Faruque Joy, Elius Hossain Bhuiyan, Md Shiful IslamSnake venom is a mixture of many biological components. Snakes usually use their venomic armory to tackle different prey and predators in adverse natural world. Among various components of the snake venom, neurotoxins play an important role in exerting effect by blocking the neuromuscular transmission through selective binding to muscle nicotinic Acetyl-Choline Receptors (nAChR). A set of 30 reference protein … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 2 · 2 Mar 2015 · 7,702 accessesView PDFCite
Research ArticleOpen accessIn the keywordsANTIOPHIDIAN ACTIVITY OF BROSIMUM GUIANENSE (AUBL) HUBERJose Adolfo Homobono Machado Bittencourt, Nayana Keyla Seabra de Oliveira, Maxwell Santos Cabral et al.Snakebites envenomations are a problem public health in worldwide due to the high rates of morbidity and mortality. The Bothrops venom causes local tissue damage and inflammation is one of the most important events that occur. At present, effective treatment for snakebites is serum therapy with antivenom, which neutralizes systemic alterations but does not prevent local damage that can cause … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 2 · 13 May 2014 · 7,784 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIdentification of Venom-Specific Fingerprints of Clinically Relevant Uruguayan Snakes by MALDI-TOFNorma Suarez, Victor MoraisSnakebite envenomation is a particular public health problem in many areas of the world, including extensive areas of Latin America. In particular, in Uruguay, snakebite accidents are caused by two snakes of the genus Bothrops: Bothrops alternatus and Bothrops pubescens. The only effective treatment available is the administration of the specific antivenom. Although there is an ELISA that allows the … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 3 · 26 Jul 2019 · 8,205 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn Vivo Neutralization of Naja nigricollis Venom by Uvaria chamaeOmale James, Ebiloma Unekwuojo Godwin, Idoko Grace OtiniUvaria chamae is a well known medicinal plant in Nigerian traditional medicine for the management of many diseases, but investigations concerning its pharmacological characteristics are rare. In this study, we evaluate its venom neutralizing properties against Naja nigricollis venom in rats. Freshly collected Uvaria chamae leaves were air dried, powdered and extracted in methanol. To study the antivenom properties, albino … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 3 · 21 Sep 2013 · 8,421 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Venom Studies on Olax viridis and Syzygium guineense ExtractsOmale James, Ebiloma Unekwuojo Godwin, Ogohi Dorathy AgahOlax viridis (Olacaceae) and Syzygium guineense (Myrtaceae) are shrubs commonly found in the tropics. They are traditional folkloric medicine for a great number of sicknesses. Olax viridis has a wide range of applications in ethnomedicine which include treatment for ulcers, veneral diseases, ringworm, sleeping sickness, diarrhea, fever. Syzygium guineense has been reported as antidiarrheal agent. Liquid from the bark and … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 1 · 12 Apr 2013 · 8,207 accessesView PDFCite
Research ArticleOpen accessIn the abstractPurification of A Recombinant Thrombin-like Enzyme, Gloshedobin by Egg Yolk Antibody-Coupled AdsorbentsQing Yang, Xuyu Lei, Jianqiang Xu, Lijia AnThe gloshedobin, a snake venom thrombin-like enzyme was biosynthesized in the soluble form and purified by egg yolk antibody-coupled adsorbents from E. coli. As His-tag is not favored from the point of view of high-level and soluble expression, we herein constructed a recombinant gloshedobin without His-tag and developed a novel egg yolk antibody (IgY)-immunoaffinity chromatography for its purification in a … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 1 · 31 Mar 2005 · 6,690 accessesView PDFCite