2 results for “Septic shock”

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Review ArticleOpen accessPhrase in the titleImmunology of Septic Shock and Traumatic Injury: A ReviewWilliam Heuser, Marianne Frieri, Krishan Kumar, Anthony BoutinSepsis remains a major worldwide cause of morbidity and mortality and remains amongst the leading causes of death in medical Intensive Care Units (ICUs). Increasing injury severity associated with trauma is a significant independent risk factor for sepsis and many of these patients require intensive care unit resource utilization with increased rates of mortality. There are many postulated theories regarding … …American Journal of Immunology, Vol. 11, Issue 4 · 31 Dec 2015 · 7,003 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsProtection against Lipopolysaccharide-induced Death by An Anti-Interleukin-6 Monoclonal AntibodyBailin Liang, Debra Gardner, Don Griswold, Xiao-yu R. SongSepticemia is frequently associated with serious complications and high mortality despite recent advances in treatment with antibacterial agents. Infectious organisms or their soluble products initiate septic shock through a complex cytokine cascade. Lipopolysaccharide (LPS) induced excessive production of inflammatory cytokines is regarded as a model of septic shock. Experiments of LPS-induced excessive cytokine production were conducted in Balb/c mice for … …American Journal of Immunology, Vol. 3, Issue 1 · 30 Jun 2007 · 6,856 accessesView PDF Cite