EditorialOpen accessIn the keywordsChronic Visceral Pain and Functional DiseasesVictor V. ChabanA functional disorder is a medical condition that impairs the normal physiological function of organs without organic cause such as inflammation. The accumulation of abnormalities that limit body functions is a major risk factor for patients with functional disorders such as Irritable Bowel Syndrome (IBS), Chronic Pelvic Pain (CPP), Painful Bladder Syndrome (PBS) and others. Often, functional disorders co-morbid by … …International Journal of Research in Nursing, Vol. 8, Issue 1 · 21 Jun 2017 · 6,992 accessesView PDFCite
HypothesisOpen accessIn the abstractCJ-023,423 (Grapiprant) a Potential Novel Active Compound with Antihyperalgetic Properties for Veterinary PatientsMario GiorgiCompanion animals are now living longer and so are more commonly manifesting age- and pain-related disease. Nonsteroidal anti-inflammatory drugs are the most used drug in osteoarthritis and inflammatory pain of various aetiologies. Despite their safety profiles have been amended from the COX-non selective to the COX-2 selective inhibitor class, some adverse effects are still of concern especially in long term … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 2 · 14 May 2015 · 8,874 accessesView PDFCite
Review ArticleOpen accessIn the abstractTransient Receptor Potential Vanilloid 1 Involvement in Animal Pain PerceptionCristina Vercelli, R. Barbero, G. ReIn last decades, Transient Receptor Potential Vanilloid 1 (TRPV1) has been the target of a large number of scientific investigations. It has been identified as a polymodal transducer molecule on a sub-set of primary sensory neurons which responds to various endogenous and exogenous stimuli including noxious heat (more than 42°C), protons and vanilloids such as capsaicin, the hot ingredient of … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 1 · 30 Mar 2015 · 7,266 accessesView PDFCite
Research ArticleOpen accessIn the abstractForensically Flies Detect the Nutritional Value of Corpses Through Neuro-Chemoreceptive Cells-(5th Cell)Hedayat Abdel Ghaffar, Tarek Tantawi, Ibrahim Gaboub et al.Animals have evolved several chemosensory systems for detecting potentially dangerous foods in the environment. Activation of specific sensory cells within these chemosensory systems usually elicits an aversive behavioral response, leading to avoidance of the noxious foods. Blowflies respond to sugars, salts and water through the activation of specific chemoreceptor neurons in the antennal, labellar and tarsal chemosensillae. These insects also … …Neuroscience International, Vol. 3, Issue 2 · 5 Sep 2012 · 7,243 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Mulberry Fruit Powder in Animal Model of StrokePratchaya Kaewkaen, Terdthai Tong-Un, Jintanaporn Wattanathorn et al.Stroke is the leading cause of death and the important cause of disability worldwide. Presently, the effectiveness of therapeutic strategy is still very limited. Based on the role neuroprotective effect of substance possessing antioxidant effect previously reported, we hypothesized mulberry fruit a substance possessing anti-oxidant activity, might be able to protect against cognitive impairment induced by stroke or cerebral ischemia. … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 3 · 15 Aug 2012 · 9,039 accessesView PDFCite