Sign inSubmit
Tips: “quotes” for a phrase · author:Lee · a DOI goes straight to its article

32 results for “Scaffold”
Set a search alert
Research ArticleOpen accessEvery word in the title3D Printing of Porous Scaffolds for Medical ApplicationsAblah Aljohani, Salil DesaiCustom engineered scaffolds that mimic the physiology of native tissue is an emerging need for successful regenerative medicine. One of the key challenges in current manufacturing methods is the lack of controlled porosity throughout the scaffold structure. In this research, our group explores the fabrication of tissue engineering scaffolds using 3D printing technology. The fused deposition modeling method was utilized … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 3 · 19 Jun 2018 · 8,508 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleHybrid Ceramo-Polymeric Nanocomposite for Biomimetic Scaffolds Design and PreparationRaffaella Aversa, Relly Victoria V. Petrescu, Roberto Sorrentino et al.Biomimetics, biomechanics and tissue engineering are three multidisciplinary fields that have been contemplated in this research to attain the objective of improving prosthetic implants reliability. Since testing and mathematical methods are closely interlaced, a promising approach seemed to be the combination of in vitro and in vivo experiments with computer simulations (in silico). An innovative biomimetics and biomechanics approach and … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 4 · 30 Nov 2016 · 8,269 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIN VITRO TESTING OF MODIFIED COLLAGEN/ HYALURONAN/BETA-GLUCAN SCAFFOLDJan Vojtassak, Dusan Bakos, Martin Bohac et al.Cells and scaffolds belong to main components of tissue engineering. In this study we have performed in vitro cytotoxicity and biocompatibility testing of modified collagen/hyaluronan/beta-glucan scaffold. We used direct contact assay as well as MTT test. Human adipose tissue-derived stem cells were used as biological model. According to obtained results, we can summarize, that modified collagen/hyaluronan/beta-glucan scaffold is non-toxic and … …OnLine Journal of Biological Sciences, Vol. 13, Issue 2 · 12 Jun 2013 · 7,214 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleInduced Microcracking Affects Osteoblast Attachment on Hydroxyapatite Scaffolds for Tissue EngineeringIan O. Smith, Melissa J. Baumann, Eldon D. CaseBone microdamage caused by routine activity plays an important role in triggering targeted and nontargeted bone remodeling. Targeted remodeling occurs near localized areas of microdamage[1-4]. We hypothesize that bone remodeling may be directly and positively influenced by inducing microcracks in hydroxyapatite (HA) scaffolds for bone tissue engineering. A study by Case et al. showed microcracking in HA discs having >98% … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 3 · 30 Sep 2006 · 6,557 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleComposite Scaffolds for Bone Tissue EngineeringMin WangBiomaterial and scaffold development underpins the advancement of tissue engineering. Traditional scaffolds based on biodegradable polymers such as poly(lactic acid) and poly(lactic acid-co-glycolic acid) are weak and non-osteoconductive. For bone tissue engineering, polymer-based composite scaffolds containing bioceramics such as hydroxyapatite can be produced and used. The bioceramics can be either incorporated in the scaffolds as a dispersed secondary phase or … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 2 · 30 Jun 2006 · 7,355 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleFabrication of 3-D Porous Mg/Zn doped Tricalcium Phosphate Bone-Scaffolds via the Fused Deposition ModellingSamar Jyoti Kalita, Melissa FergusonThree dimensionally interconnected porous resorbable beta-tricalcium phosphate (β-TCP) ceramic scaffolds were developed using the indirect fused deposition modelling process. β-TCP was doped with Mg and Zn, separately, to improve its sintering kinetics and facilitate fabrication of viable porous scaffolds. Effects of Mg and Zn on sintering kinetics and densification of β-TCP were studied. Fabricated porous scaffolds were tested for their … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 2 · 30 Jun 2006 · 6,926 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSequence Analysis of Scaffold/Matrix Attachment Regions (S/MARs) From Human Embryonic Kidney and Chinese Hamster Ovary CellsNur Shazwani Mohd Pilus, Azrin Ahmad, Nurul Yuziana Mohd YusofBinding of intergenic Scaffold/Matrix Attachment Regions (S/MARs) to nuclear matrix proteins is believed to poise adjacent genes for transcription by forming chromatin loops. Vector constructs containing Scaffold/Matrix Attachment Regions (S/MAR) flanking the gene of interest, therefore, are able to enhance recombinant protein expression in mammalian cells. We compared two methods that are based on buffers containing 2M NaCl and Lithium-3,5-diidosalicylate … …OnLine Journal of Biological Sciences, Vol. 18, Issue 4 · 8 Oct 2018 · 7,630 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleGrowth of Bone Marrow Derived Osteoblast-Like Cells into Coral Implant Scaffold: Preliminary Study on Malaysian CoralK. A. AL-SalihiProblem statement: Biomaterial fabrication in Malaysia started as a consequence of the demand for cheaper implant materials. Various biomaterials have been developed utilizing local resources like Malaysian coral. Locally processed Malaysian coral need to be complemented with proper evaluation and testing including toxicology, biocompatibility, mechanical properties, physicochemical characterization and in vivo testing. The present study was carried out to assess … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 3 · 30 Sep 2009 · 6,590 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleClosing the Gaps in Rat Cytomegalovirus ALL-03 (Malaysian Strain) Genomic ScaffoldKrishnan Nair Balakrishnan, Ashwaq Ahmed Abdullah, Yusuf Abba et al.Next generation sequencing technologies has revolutionized genomic research by producing a large volume of sequence data and lowest per base cost compared to the traditional sanger method. Although this technology offers many advantages, gap occurrences are commonly found in draft assemblies. The same problem was observed with Rat Cytomegalovirus (RCMV) ALL-03 (Malaysia strain), where a complete genome sequence could not … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 3 · 8 Jun 2015 · 7,578 accessesView PDFCite
Research ArticleOpen accessIn the keywordsDevelopment of Cell-Responsive Nanophase Hydroxyapatite for Tissue EngineeringR. Murugan, S. RamakrishnaScaffold plays a critical role in engineering bone tissues by providing necessary structural support for the cells to accommodate and guiding their growth in the three dimensional (3D) space. Therefore, designing scaffold that mimic composition and structural aspects of the bone is of great importance to promote cell adhesion, cell-matrix interactions, osteointegration, tissue formation and continued function. Nanophase hydroxyapatite (HA) … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 3 · 30 Sep 2007 · 7,163 accessesView PDFCite