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58 results for “Safety Assessment”
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Research ArticleOpen accessPhrase in the titleSafety Assessment of Indigenous Probiotic Strain Lactobacillus plantarum Mut-7 Using Sprague Dawley Rats as a ModelAtika Yahdiyani Ikhsani, Emma Riftyan, Rosa Amalia Safitri et al.Lactobacillus plantarum Mut-7 is a probiotic candidate isolated from gatot, traditional fermented cassava from Java, Indonesia. This study aimed to evaluate safety aspects of high dose consumption of L. plantarum Mut-7 (1011 CFU/ml/day) on Sprague Dawley rats for 21 days. Twenty four female rats were randomly divided into 4 groups; initial condition group (P.0), control group (P.1), skim milk group … …American Journal of Pharmacology and Toxicology, Vol. 15, Issue 1 · 30 Apr 2020 · 8,690 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleSafety Assessment of Indigenous Probiotic Strain Lactobacillus plantarum Dad-13 Isolated from Dadih Using Sprague Dawley Rats as a ModelEndang S Rahayu, Ilzamha H Rusdan, Armita Athennia et al.Lactobacillus plantarum Dad-13 is a probiotic candidate from dadih, a traditional fermented buffalo milk from West Sumatera, Indonesia. This study aimed to evaluate safety aspects of L. plantarum Dad-13 in high dose consumption on Sprague Dawley rats. Two treatment groups were fed with 1011 CFU/mL/day of L. plantarum Dad-13 for 14 and 28 days respectively. Two placebo groups were fed … …American Journal of Pharmacology and Toxicology, Vol. 14, Issue 1 · 12 Nov 2019 · 10,134 accessesView PDFCite
Research ArticleOpen accessPhrase in the titlePolygonatum sibiricum Red. With Steaming Yellow Rice Wine: Processing Technology, the Content of 5 Hydroxymethylfurfura and Safety AssessmentShiyu Ji, Shuo Li et al.To investigate the content and safety evaluation of 5 Hydroxymethylfurfural (5-HMF) in the processing of Polygonatum sibiricum Red, the steaming technology was optimized by response surface method combined with analytic hierarchy process of multiple indexes. The content of 5-HMF was quantitatively determined by HPLC. Safety assessment was conducted using a zebrafish model. The optimized conditions were a steaming time of … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 20 Nov 2025 · 2,587 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleGastroprotective Effect and Safety Assessment of Zanthoxylum Zanthoxyloides (Lam) Waterm Root Bark ExtractAlex Boye, George Asumeng Koffuor, Johnson Nyarko Boampong et al.Problem statement: Gastrointestinal ulcers account significantly for morbidity and mortality in Ghana. The study therefore investigated the gastroprotective effect of an ethanolic root bark extract of Zanthoxylum zanthxyloides and its safety for us. Approach: Gastric ulceration was induced in Sprague-Dawley rats with Indomethacin (25 mg kg-1, p.o) and was treated with 150, 250, or 500 mg kg-1 of the extract, … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 2 · 7 Aug 2012 · 8,495 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleSafety Assessment of Herbal Formulations, Rumbion™ and Tyrel™ in Albino Wistar RatsA.J. Joshua, K.S. Goudar, N. Sameera et al.Problem statement: Herbal remedies form one of the effective strategies for management of livestock healthcare. Despite the availability of extensive pharmacological information, the toxicological data on herbs and herbal preparations seem to be scanty. The objective of the present investigation was to evaluate the acute oral toxicity of some herbal veterinary preparations in albino Wistar rats. Approach: In the sighting … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 1 · 31 Mar 2010 · 8,544 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleTraditional Aquaculture Practice at East Calcutta Wetland: The Safety AssessmentS. Raychaudhuri, M. Mishra, S. Salodkar et al.The current study is on East Calcutta Wetland (ECW) which is a model for multi-use resource recovery system with activities like pisciculture and agriculture. The entire city's soluble waste is disposed into the raw sewage canals which finally drains into the shallow, flat bottom fish ponds called Bheri. These sewage fed fisheries act simultaneously for the purification process like removal … …American Journal of Environmental Sciences, Vol. 4, Issue 2 · 30 Apr 2008 · 9,436 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleElectromagnetic Assessment on Human Safety of Mobile Communication Base Stations at University of MacauK.H. Chiang, K.W. TamAssessment of the electromagnetic exposure due to the mobile communication base station at University of Macau is presented by two testing scenarios. The first scenario about 20 in-situ measurements and the maximum E-field strength was 2.46 V/m that well below the threshold and compliant to the safety guideline. The second scenario investigates on the distance effect of exposure due to … …American Journal of Applied Sciences, Vol. 5, Issue 10 · 31 Oct 2008 · 6,752 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleOccupational Safety and Health in Tunnelling in Rocks Formations Potentially Containing Asbestos: Good Practices for Risk Assessment and ManagementDavide Labagnara, Mario Patrucco, Achille SorliniIn tunnelling operations, Occupational Safety and Health (OS&H) and Environmental Protection of the areas close to the tunnel portal become even more critical in case of rock formations potentially containing asbestos, quartz, radioactive elements, etc. In order to limit the workers’ exposure and the environmental impact becomes in these cases of paramount importance to preliminarily analyze and quantify the possible … …American Journal of Applied Sciences, Vol. 13, Issue 5 · 26 May 2016 · 7,646 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIn Silico, In Vitro and In Vivo Assessment of Safety and Anti-inflammatory Activity of CurcuminM. Venkata, R. Sripathy, D. Anjana et al.Problem statement: Curcumin the active component of turmeric is known for its wide biological actions. Extensive studies on curcumin highlighted its anti-inflammatory, anti-oxidant, anti-microbial, anti-carcinogenic and anti-coagulant activity. The anti-inflammatory activities of curcumin have been demonstrated both in vitro and in vivo. Though curcumin and its anti-inflammatory properties are well documented, the exact mechanism of action and effective in vivo … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 23 Feb 2012 · 8,999 accessesView PDFCite
Research ArticleOpen accessIn the keywordsNON-CANCER HUMAN HEALTH RISK ASSESSMENT FROM EXPOSURE TO HEAVY METALS IN SURFACE AND GROUNDWATER IN IGUN IJESHA, SOUTHWEST NIGERIAO. O. Ayantobo, J. A. Awomeso, G. O. Oluwasanya et al.Non-cancer hazard index for inhabitants exposed to heavy metals in surface and groundwater of the abandoned metal mine in Igun-Ijesha area were evaluated. A total of thirty-eight water samples were collected from surface and ground water sources in the study area between September 2012 and February 2013 and the concentrations of heavy metals were determined using Atomic Absorption Spectrophotometer. Non-cancer … …American Journal of Environmental Sciences, Vol. 10, Issue 3 · 10 May 2014 · 8,769 accessesView PDFCite