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116 articles for “SIR”
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Research ArticleOpen accessEvery word in the titleSIR Transmission Model of Dengue Virus Taking Into Account Two Species of Mosquitoes and an Age Structure in the Human PopulationR. Sungchasit, P. Pongsumpun, I. M. TangDengue is a vector-borne disease. It is transmitted to humans by the bites of the Aedes aegypti and Aedes albopictus mosquitoes. The human population is separated into two classes, a child class and an adult class, each class being described by a SIR model. The transmission rates of the two mosquito species are different and depend on what class the … …American Journal of Applied Sciences, Vol. 12, Issue 6 · 28 Jul 2015 · 6,511 accessesView PDFCite
Research NotesOpen accessEvery word in the titleNuciferine Attenuates Cigarette Smoke-Induced Senescence in HepG-2 Cells via the miR-217/SIRT1/Nrf2 PathwayYun-Hong Zhao, Yi-Meng Ge, Wei-Jia Xu et al.The lotus leaf, widely used in both medicine and cuisine, contains bioactive compounds with therapeutic potential. Nuciferine (NF), an active constituent of significant importance, is extracted from the lotus leaf. The present study sought to uncover the molecular pathways through which Nuciferine (NF) mitigates cellular senescence triggered by Cigarette Smoke Components (CSCs) in HepG-2 cells, employing an experimental model where … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 4 Oct 2025 · 2,296 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleSIRT1 Controls Lipid Metabolism Under Physiological and Pathological Conditions: Implications in AtherosclerosisAnastasia Vladimirovna Poznyak, Ludmila Viktorovna Nedosugova, Victoria Alexandrovna Khotina et al.This comprehensive review examines the multifaceted role of Sirtuin 1 (SIRT1) in cellular metabolism and energy regulation, with a particular focus on its involvement in lipid metabolism and glucose regulation. Additionally, SIRT1's impact on several pathologies, including osteoarthritis, diabetes, and cardiovascular disease, is explored. Notably, this review sheds light on the unique contribution of SIRT1 in the development and progression … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 7 Jun 2024 · 4,739 accessesView PDFCite
Literature ReviewOpen accessEvery word in the titleAtherosclerosis as Age-Related Disease: The Potential of Sirtuins TreatmentAnastasia Vladimirovna Poznyak, Victor Yurievich Glanz, Vasily Nikolaevich Sukhorukov et al.Atherosclerosis, a global health concern, has attracted researchers worldwide due to its severe consequences. The elderly are particularly susceptible to cardiovascular diseases and events, making them a high-risk group. Although gaps in our understanding of atherosclerosis pathogenesis persist, it is evident that oxidative stress, endothelial dysfunction, inflammation, mitochondrial dysfunction, and autophagy impairments are key components of its development. Remarkably, these … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 16 May 2024 · 4,717 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleRelative Transcription Expression Level of SIRT1, SIRT2 and SIRT3 in Correlation to the Expression of a Set of Selected Cancer Related Genes in Human Breast CancerHamdy Swelim, Omnia Mansour, Salah Abdel-Rahman et al.Mammalian Sirtuins have been shown to perform distinct cellular functions and deregulated expression of these genes was reported to be involved in the development of various malignancies including breast cancer. An increasing number of evidence indicates that Sirtuins have both tumor promoter and tumor suppressor functions. However, the roles of Sirtuins have not been well-studied in breast cancer. In the … …OnLine Journal of Biological Sciences, Vol. 18, Issue 2 · 18 Jan 2018 · 7,476 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleAn Insight into the Simplified RP Transmission Network, Concise Baseline and SIR Models for Simulating the Transmissibility of the Novel Coronavirus Disease 2019 (COVID-19) OutbreakEva Gupta, Nand Jee KanuThe World Health Organization has reported about a Severe Acute Respiratory Syndrome, Coronavirus 2 (SARS-CoV2) (a virus of Wuhan, China pneumonia). The present investigation explores the transmissibility of the novel Coronavirus Disease (COVID-19) using some suitable mathematical models such as (a) a simplified Bats-Hosts-Reservoir (Wuhan Seafood Market)-People (BHRP) transmission network model useful in mapping the spread of the novel COVID-19 … …American Journal of Infectious Diseases, Vol. 16, Issue 2 · 1 Jul 2020 · 7,586 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleApplication of Homotopy Perturbation Method for SIR Model with Vital Dynamics and Constant PopulationMohammed S. Mechee, Ghassan A. Al-JuaifriIn this work, we have studied Susceptible-Infected-Recovered (SIR) model with vital dynamics and constant population, which is used as a mathematical models in many physically significant fields of applied science. The Homotopy Perturbation Method (HPM) and Runge-Kutta method (RK) have been used for solving the SIR model with vital dynamics and constant population. The convergence of HPM has been studied. … …American Journal of Applied Sciences, Vol. 15, Issue 1 · 3 Jan 2018 · 8,003 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEstimation of Adaptability and Stability of Nellore Sires, based on the Productive Progeny Performance Raised in Brazilian SavannaJúlio César De Souza, Fabio Fábio Rafael Leão Fialho, Carolina Fregonesi De Souza et al.The study investigates the performance and adaptability of Nellore sires across different regions, focusing on weight traits at 205 days (W205) and 550 days (W550). Analysis reveals significant variations in progeny weight means among evaluated sires, highlighting the importance of sire selection for herd improvement. Notably, certain sires consistently exhibit superior weight traits across diverse environmental conditions, indicating their potential … …American Journal of Agricultural and Biological Sciences, Vol. 19, Issue 1 · 2 Jul 2024 · 5,529 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCell Longevity of Yeast Saccharomyces cerevisiae by Clove Bud Extract Treatment May Occur in Sirtuin-Independent PathwayZahrah Qolbaina Ariybah, Rika Indri Astuti, Sri ListiyowatiAccumulation of free radicals causes cell damage that leads to a phenomenon called aging. Antioxidant application is one potential strategy to avoid the damage of free radical accumulation. Many reports resume that clove, one of Indonesia’s spices, contain high amount of antioxidant. Our previous research had proven that clove extract could extend longevity in yeast Saccharomyces cerevisiae. However, cellular mechanism … …OnLine Journal of Biological Sciences, Vol. 21, Issue 3 · 3 Aug 2021 · 6,659 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleGO-NGO Support in Selected Char Areas of Sirajganj District in Bangladesh: Impact on Crop Profitability and Farmers’ Income GenerationAurup Ratan Dhar, Arifa Jannat, Md. Monirul IslamThe study was carried out to elucidate the GO-NGO support on farmers’ income generation in selected char areas of Sirajganj district. Following purposive sampling technique, a total of 60 farmers (30 non-supported and 30 GO-NGO supported) were selected for the study. Descriptive statistics, mathematical and statistical analyses were used to analyze the collected data from field survey method. The average … …American Journal of Agricultural and Biological Sciences, Vol. 12, Issue 3 · 23 Oct 2017 · 8,514 accessesView PDFCite