2 articles for “Robert Lew”

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Research ArticleOpen accessIn the author namesDesign Based on Intra-Class Correlation CoefficientsRobert Lew, Gheorghe DorosProblem statement: Reliability studies are concerned with the study of "consistency" or "repeatability" of measurements. Often times (but not always) the reliability coefficients are Intra-class Correlation Coefficients (ICC). Depending on the design or the conceptual intent of the study there are three types of intra-class correlation coefficients, termed intra-class correlation coefficients Case 1, 2 and 3, for measuring the reliability … …Current Research in Biostatistics, Vol. 1, Issue 1 · 30 Jun 2010 · 18,541 accessesView PDF Cite

Research ArticleOpen accessIn the author namesThe Autistic Phenotype Exhibits a Remarkably Localized Modification of Brain Protein by Products of Free Radical-Induced Lipid OxidationTeresa A. Evans, Sandra L. Siedlak, Liang Lu et al.Oxidative damage has been documented in the peripheral tissues of autism patients. In this study, we sought evidence of oxidative injury in autistic brain. Carboxyethyl pyrrole (CEP) and iso[4]levuglandin (iso[4]LG)E2-protein adducts, that are uniquely generated through peroxidation of docosahexaenoate and arachidonate-containing lipids respectively, and heme oxygenase-1 were detected immunocytochemically in cortical brain tissues and by ELISA in blood plasma. Significant … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 8,724 accessesView PDF Cite