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1 result for “Renin-Angiotensin-Aldosterone System (RAAS)”

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Research ArticleOpen accessIn the keywordsRenal Actions of Neutral Endopeptidase Inhibition in Rats with Chronic Heart FailureAmr M. Abbas, Ayman Z. Elsamanoudy, Adel ZalataProblem statement: We aim to evaluate the effects of acute and chronic inhibition of Neutral EndoPeptidase (NEP), by ONO-9902, on plasma and renal NEP gene expression, hemodynamic and renal parameters in rats with Chronic Heart Failure (CHF) following left Coronary Artery Ligation (CAL). Approach: Forty eight male Sprague-Dawley rats (220-240 g) were divided into sham and CAL groups. Myocardial infarction … …American Journal of Applied Sciences, Vol. 7, Issue 11 · 8 Nov 2010 · 7,087 accessesView PDFCite