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185 results for “Receptor”
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Review ArticleOpen accessEvery word in the titleFrom Health to Disease: Functional Insights of Scavenger Receptor Class B Type I in Lipid Metabolism and Disease PathogenesisSujina Simon Sailet, Poornima Ajay Manjrekar, Santosh Rai et al.Scavenger receptor class B type I (SR-B1) has caught considerable interest among the scientific community due to its pivotal role in several biological and pathological processes. It is a multifunctional integral membrane protein and multiligand receptor encoded by the SCARB1 gene. SR-B1 has a wide distribution, primarily in the liver as well as steroidogenic organs including the gonads and adrenal … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 11 Jul 2025 · 3,667 accessesView PDFCite
Research NotesOpen accessEvery word in the titleHistopathological Characterization and Expression of Vitamin D Receptor in the Prostate of Healthy Dogs and Dogs with Prostatic CarcinomaAkiko Ikeda, Masanori Kobayashi, Tatsuya Hori et al.Vitamin D Receptor (VDR) expression is implicated in human Prostatic Carcinoma (PC), but its role in canine PC is unclear. To investigate how VDR expression is affected by age and castration in healthy dogs and how it changes with PC, we evaluated prostates from 8-month-old (n = 5) or 6-year-old (n = 8) intact males, 1-8-year-old healthy castrated males (n … …American Journal of Animal and Veterinary Sciences, Vol. 18, Issue 1 · 24 Feb 2023 · 5,291 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDifferent Arrangement of Dopamine Receptors/NMDA Receptors Heterocomplexes in the Brain Regions of a Healthy Male, Female and Audiogenic Seizure-Prone Male RatsGigi Tevzadze, Elene Zhuravliova, Natia Okriashvili et al.Differences in the composition and subcellular localization of heteroreceptors in the brain can trigger central nervous system diseases, including epilepsy and autism. Protein-protein interactions between Dopamine Receptors (DRs) and GLUN2A and GLUN2B subunits are critical mechanisms that regulate dopamine and glutamate coordinated signals. These interactions may be involved in the pathophysiological predisposition of epilepsy. We hypothesized that the specificity of … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 2 · 27 Apr 2022 · 6,098 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCorrelation of Oxytocin (OTR) and Estrogen Receptor (ER) mRNA in the Canine Placenta with the Detected Circulating Levels of Oxytocin and Estrogen during Pregnancy and ParturitionGisele Almeida Lima Veiga, Marcella Pecora Milazzotto, Marcilio Nichi et al.Placenta is considered an important endocrine organ during gestation, as well as can also serve as a target organ for sex steroids and pituitary hormones, mainly for the cascade of events that trigger parturition. In order to initiate studies on the canine placental endocrinology regarding estrogen and oxytocin, the present study verified the correlation among the Estrogen Receptor alpha (ERα) … …American Journal of Animal and Veterinary Sciences, Vol. 11, Issue 1 · 31 Dec 2015 · 8,272 accessesView PDFCite
EditorialOpen accessEvery word in the titleCommentary-How do we Improve Training for Receptor Research?Marilee Ann BenoreThis issue of the American Journal of Biochemistry and Biotechnology features articles about receptor-ligand interactions that are critical to the wellbeing of all living organisms. The importance of the field of receptor research is supported by the large number of articles published in journals, the numerous specialty journals, the international conferences and the percentage of legal drugs on the market … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 4 · 8 Dec 2015 · 8,056 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleExpression Pattern of the Orphan Nuclear Receptor, Nurr1, in the Developing Mouse Forelimb and its Relationship to Limb Skeletogenesis and OsteogenesisHeba A. Ahmed, Lidia L. Ibrahim, Desouki A. El Mekkawy, Abeer El WakilThe NR4A orphan nuclear receptor, Nurr1, has been shown to regulate the expression of osteoblastic genes and osteoblastic differentiation. However, the expression profile of Nurr1 in the developing mouse forelimb and its relationship to skeletogenesis has not, to the best of our knowledge, been previously analyzed. In this study, the relationship between Nurr1 expression pattern, skeletogenesis and osteogenesis in the … …OnLine Journal of Biological Sciences, Vol. 15, Issue 3 · 24 Jul 2015 · 6,950 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleHost Receptor Immunomodulation in Response to Shigella Surface Antigens: An Insight for Vaccine DevelopmentAshim K. Bagchi, Rushita A. Bagchi, Dipak K. Hens et al.Shigellosis, caused by Shigella is the most common cause of bacillary dysentery. The disease is associated with high morbidity and mortality rate owing to its multiple drug resistance. Hence recovery from the disease would primarily depend on the development of an effective immune-modulator for strong mucosal immune response. The role of cellular immunity may be a critical factor in protection … …American Journal of Immunology, Vol. 11, Issue 2 · 21 Jun 2015 · 6,752 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCastration and Passive Avoidance Learning Alter the Distribution of N-Methyl D-Aspartate ReceptorSeyed Hassan Mirzaei, Mahnaz Taherianfard, Mina Tadjali, Mahbobeh KohkaloyehIn neurophysiological studies on learning and memory, L-glutamate receptors especially N-Methyl, D-Aspartate glutamate (NMDA) receptors have a major role in different aspect of the learning and memory. Two sites of mammalian brain that show high density of these receptors are CA1 region of hippocampus and Purkinje cell layer of cerebellum. Twenty four Sprague-Dawley rats were used in 4 groups: Control … …Neuroscience International, Vol. 4, Issue 2 · 1 Apr 2014 · 6,773 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleStructural Consequences of the Polymorphism Q223R in the Human Leptin Receptor: A Molecular Dynamics StudyJonathan P. Carrillo-Vázquez, Brenda Chimal-Vega, Beatriz Zamora-López et al.Leptin Receptor (LEPR) is a component of a signaling pathway related to appetite and energy expenditure. Single Nucleotide Polymorphisms (SNP) of Leptin receptor gene (lepr) have been proposed as possible modulator of adipose tissue and body weight. The main phenomenological consequence reported of these SNPs is the modulation of the LEP-LEPR interaction promoting the weight gain. Particularly, Q223R polymorphism has … …American Journal of Agricultural and Biological Sciences, Vol. 8, Issue 3 · 23 Sep 2013 · 7,835 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleModulation of the GABAA Receptor by Srif in Rat ThalamusFatiha Chigr, Mariama El Ouahli, Ghizlane Er-Raoui et al.Somatostatin has been reported to modulate GABAA receptor complex in many brain structures. This study was conducted to investigate somatostatin modulation of the GABAA receptor binding in several rat diencephalic structures, focusing primarily on the thalamus, as this structure plays important roles. Animals were assigned to control conditions. Changes in specific binding of GABAA receptor as labelled with [35S]t-Butylbicyclophosphorothionate (TBPS) … …Neuroscience International, Vol. 3, Issue 2 · 14 Sep 2012 · 6,963 accessesView PDFCite