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39 results for “Rat Model”
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Research ArticleOpen accessPhrase in the titleHuman Adipose Stem Cells in Collagen on Angiogenesis Process of Burn Healing in Rat Model: Its Number of Blood VesselsLuluk Yunaini, Puji Sari, Dwi Pratami Septiara et al.Angiogenesis in the burn wound healing process is important. The application stem cell therapy in burn wound problem is expected to increase formation of new blood vessel so that the distribution of oxygen and nutrients working well. The purpose of this study was to known effect of human Adipose Derived Stem Cell (hADSC) in collagen gel on the average number … …OnLine Journal of Biological Sciences, Vol. 19, Issue 1 · 7 Jan 2019 · 7,600 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleTHE IMPACT OF ANTIOXIDANTS ON INFLAMMATION AND OXIDATIVE STRESS MARKERS IN OSTEOARTHRITIS RAT MODEL: SCANNING ELECTRON MICROSCOPE INSIGHTSEl Hassan Heidar, FareedF Al Faya, Waleed N. Hassan et al.Osteoarthritis (OA) is characterized by degradation of matrix and destruction of articular cartilage. Articular chondrocytes are solely responsible for the production and maintenance of the extracellular matrix. Therefore, chondrocyte disruption is implicated in cartilage degeneration. Numerous studies have shown that antioxidant treatments are promising therapeutics in cases of OA. This study was designedto examine whether vitamin E protects rat articular … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 2 · 19 May 2014 · 7,616 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleEndothelial Dysfunction and Insulin Resistance as Pathophysiologic Mechanisms in a Rat Model of PreeclampsiaAyman Z. Elsamanoudy, Amr M. AbbasProblem statement: To assess the plasma concentrations and placental gene expression of soluble fms like tyrosine kinase (sFlt-1), Vascular Endothelial Growth Factor (VEGF), visfatin and Tumour Necrosis Factor α (TNFα) in a rat model of preeclampsia, induced by chronic Reduction of Uterine Perfusion Pressure (RUPP) and to investigate the involvement of Insulin Resistance (IR) in the pathophysiology of preeclampsia and … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 3 · 30 Sep 2010 · 7,503 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleImmunodeficient Parameters in the HIV-1 Transgenic Rat ModelSulie L. Chang, Frank Ocasio, Jose A. BeltranRecently an HIV-1 transgenic (HIV-1Tg) rat model was created that carries a gag-pol-deleted HIV-1 genome under the control of the HIV-1 viral promoter. However, other viral proteins are expressed in most organs and tissues, and are found in the circulating blood. Since HIV-1 targets the immune system in humans, we examined two immunological parameters, leukocyte-endothelial adhesion (LEA) and inflammatory cytokine … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,834 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleGalactomannan Restore Letrozole Induced Polycystic Ovarian Syndrome (PCOS) in Rat ModelManoj K. Aswar, Utkarsha V. Deshpande, Urmila AswarCurrent research aims towards evaluation of the effect of Galactomannan (GM) on letrozole-induced PCOS in adult female Wistar rats. Seven randomized groups of six female rats were made. The rats in all groups were administered with letrozole (1 mg/kg p.o.) for 21 days to induce PCOS. Rats in respective groups were treated with vehicle (10 ml/kg, p.o.), clomiphene citrate (1 … …American Journal of Pharmacology and Toxicology, Vol. 16, Issue 1 · 1 Dec 2021 · 7,482 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleRat Model for Poly-AutoimmunityMaria StaykovaAround 30% of the male PVG rats have very low testosterone levels. Upon immunisation with myelin basic protein in complete Freund’s adjuvant they develop experimental autoimmune encephalomyelitis and adjuvant arthritis. The androgen insensitive syndrome in these rats could be used in studies on poly-autoimmunity as well as in studies on variations in the sexual differentiation of brain and behavior. …American Journal of Immunology, Vol. 8, Issue 3 · 7 Sep 2012 · 7,549 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleProtective Effect of Enicostemma littorale Blume on Rat Model of Diabetic NeuropathyNiraj Mukundray Bhatt, Suparna Barua, Sarita GuptaProblem statement: Poor glycemic control and oxidative stress is implicated as a common pathway in the development of diabetic neuropathy. Approach: In the present study, we investigated the protective effects of Enicostemma littorale Blume (EL) (2.5 g kg-1), a hypoglycemic and antioxidant herbal medicine in alloxan-induced diabetic neuropathy in male Charles foster rats. Results: Tail flick latency in hot immersion … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,838 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleRole of HIV-1 Infection in Addictive Behavior: A Study of a HIV-1 Transgenic Rat ModelSulie L. Chang, Michael VigoritoEpidemiological research indicates that drug abuse is prevalent among individuals infected with HIV-1. Evidence from preclinical research also suggests that drugs of abuse exacerbate the progression of neuropathological changes in the HIV-1 infected brain probably through common mechanisms of neuronal injury. The effects of HIV-1 on the efficacy and abuse potential of controlled drugs such as morphine, however, has not … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 7,630 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleInfluence of Degrading Calcium Phosphate on the Remodelling and Mineralisation of Avascular Osseous Tissue in a Rat Calvaria ModelTulio Fernandez, Carlos H. Valencia, Yuann Li et al.Artificial bone graftingis the subject of intensive investigation for craniofacial reconstruction. Among the syntheticcandi date materials, those incorporating Calcium Phosphates (CaP) have gained popularity, due to their osteoinductive properties. Despite many quantitative studies on the degradation rates of CaP biomaterials in vitro, there is lack of quantitative studies in relation to bone remodelling kinetics in vivo. In this investigation, we … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 1 · 24 Dec 2014 · 7,208 accessesView PDFCite