Research ArticleOpen accessIn the keywordsMagnum Opus: Clustered Regularly Interspaced Short Palindromic Repeats Biology and Prokaryotic Gene SilencingPrem Saran Tirumalai, Ashim Kumar BagchiGene Silencing was a technology that was established in eukaryotic system a decade ago and is being used as a research tool widely. However, prokaryotic gene silencing was not workable, till recently a team of researchers from the University of Georgia have proved it possible. Where they have shown that short motif sequences determines the targets of the prokaryotic Clustered … …American Journal of Immunology, Vol. 9, Issue 4 · 5 Oct 2013 · 7,144 accessesView PDFCite
Research ArticleOpen accessIn the abstractMetabolic Potential Versus Genome SizeAtanas Todorov Atanasov, Dimitar Todorov ValevAlberch, P. (1983). Development and Evolution: Embryos, Genes, and Evolution. The Developmental-Genetic Basis of Evolutionary Change. Science, 221(4607), 257–258. https://doi.org/10.1126/science.221.4607.257 Andrews, C. B., Mackenzie, S. A., & Gregory, T. R. (2009). Genome size and wing parameters in passerine birds. Proceedings of the Royal Society B, 276(1654), 55–61. https://doi.org/10.1098/rspb.2008.1012 Atanasov, A. T. (2005). The linear alometric relationship between total metabolic energy … …Physics International, Vol. 13, Issue 1 · 15 Jun 2022 · 7,229 accessesView PDFCite
EditorialOpen accessIn the abstractRe-Paving the Road Built by Chemistry: A Challenge to Biochemistry and BiotechnologyAlberto A. IglesiasBiochemistry’s birth can be placed at the end of the nineteenth century, when Eduard Buchner made a clever interpretation of experimental observations on the generation of gas bubbles after addition (the original purpose was preservation) of sucrose to a yeast crude extract (Lagerkvist, 2005). Intelligently, Buchner concluded that the disaccharide had been fermented by broken cells’ suspension to produce CO2, … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 1 · 26 Jan 2015 · 7,461 accessesView PDFCite
Research ArticleOpen accessIn the abstractStructural and Evolutionary Analysis of PARPs in D. discoideumA. Mehadvi Kawal, Hina A. Mir, Chethan Kumar Ramniklal et al.Problem statement: Dictyostelium discoideum, a unicellular eukaryote, exhibits multicellularity upon nutrient starvation, making it a better model for developmental studies and for the study of various signal transduction pathways. The most felicitous point of interest is that many of its genes show high degree of similarity to vertebrate genes. Poly (ADP-ribose) polymerase (PARP), a ubiquitous and abundant nuclear protein, has … …American Journal of Infectious Diseases, Vol. 7, Issue 3 · 3 Nov 2011 · 7,852 accessesView PDFCite
Research ArticleOpen accessIn the abstractUnique Characteristic Features of Mycobacterium Tuberculosis in Relation to Immune SystemRajni, Laxman S. MeenaProblem statement: Tuberculosis is a leading global mortality factor which has not been effectively controlled, with 1.7 million deaths per year and 8.9 million new cases. Aerobic microbe Mycobacterium Tuberculosis H37Rv (MTB) is the causative agent of tuberculosis. Approach: It is unique among prokaryotes due to its exceptional features contributing to its survival within the hostile environment of macrophages. Results: … …American Journal of Immunology, Vol. 7, Issue 1 · 16 Aug 2011 · 17,211 accessesView PDFCite