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Research ArticleOpen accessIn the keywordsAPPLICATION OF THE MEDIATION ANALYSIS APPROACH TO CANCER PREVENTION TRIALS RELATING TO CANCER SEVERITYYasutaka ChibaIn a cancer prevention trial, an outcome such as cancer severity cannot be evaluated in individuals who do not develop cancer. In such a situation, the principal stratification approach has been applied. Under this approach, the Principal Strata Effect (PSE) has been considered, which is defined as the effect of treatment on the outcome among the subpopulation in which individuals … …Current Research in Biostatistics, Vol. 4, Issue 2 · 6 Jan 2015 · 7,195 accessesView PDF Cite

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