5 results for “Postmenopausal”

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Research ArticleOpen accessIn the keywordsThe Role of Receptor Activator of Nuclear Factor Kappa B (RANK) and Receptor Activator of Nuclear Factor Kappa B Ligand (RANKL) in Osteoporosis Risk: Gene Polymorphism and Soluble RANKL Level in Indonesia Post-Menopausal WomenLuluk Yunaini, Dwi Anita Suryandari, Linda Kusdhany et al.Hormonal changes in postmenopausal women may increase osteoclastogenesis that can lead to increased risk of osteoporosis. Receptor Activator of Nuclear factor Kappa B (RANK) and Receptor Activator of Nuclear factor Kappa B Ligand (RANKL) have an important role in osteoclastogenesis that involve in the regulation of bone resorption. In this study, we analyzed the Single Nucleotide Polymorphism (SNPs) within the … …OnLine Journal of Biological Sciences, Vol. 18, Issue 3 · 27 Sep 2018 · 8,183 accessesView PDF Cite

Research ArticleOpen accessIn the abstractInverse Correlation Between α-Klotho and Diabetic Biomarkers in Type 2 Diabetes: A Cross-Sectional StudyYaser A.M Sulaiman, Moayad M. Al Anzy, Omeed Akbar Ali, Adnan M. IsmailEvidence suggests a link between diabetes and Klotho protein, demonstrated by reduced Klotho gene expression in individuals with diabetes, α- klotho the potential modulator of kidney health in DM. Klotho is primarily expressed in the kidneys and has an anti-inflammatory and antioxidant role, which may protect against the pathological processes that damage renal function in diabetes. Research conducted in Japan … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 2 Jul 2026 · 843 accessesView PDF Cite

Research ArticleOpen accessIn the abstractCross Talk between Iron Regulatory Proteins and Proinflammatory Molecules in Ovarian Cancer Patients Based on Menopausal StatusHaritha Padannapurath Manoj, Sudha Kuthethur, Reshma Kumarchandra et al.Micronutrient iron is postulated to contribute to the initiation of cancer mainly by the formation of Reactive Oxygen Species (ROS), the key signaling molecules of inflammatory reactions. Iron may also cause elevation of MMP9, a gelatinase responsible for remodeling extracellular matrix in cancer cells through the ROS pathway. Estrogen the hormone which decreases markedly in post menopause is also known … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 31 May 2024 · 4,494 accessesView PDF Cite

EditorialOpen accessIn the abstractPLANT STEROLS LOWER CHOLESTEROL, BUT INCREASE RISK FOR CORONARY HEART DISEASEZoë Harcombe, Julien S. BakerAssmann, G., P. Cullen, J. Erbey, D.R. Ramey and F. Kannenberg et al., 2006. Plasma sitosterol elevations are associated with an increased incidence of coronary events in men: Results of a nested case-control analysis of the Prospective Cardiovascular Munster (PROCAM) study. Nutr Metab Cardiovasc Dis., 16: 13-21. BfR, 2011. Addition of plant sterols and stanols to food: Assessment of a … …OnLine Journal of Biological Sciences, Vol. 14, Issue 3 · 21 Aug 2014 · 89,005 accessesView PDF Cite

Research ArticleOpen accessIn the abstractG-2548A Leptin Promoter and Q223R Leptin Receptor Polymorphisms in Obese Mexican SubjectsP. Carrillo-Vazquez Jonathan, Lopez-Alcantar Jeronimo, Chimal-Vega Brenda et al.Leptin interaction with its receptor in the hypothalamus stimulates a specific signaling cascade that results in the synthesis of anorexigenic and orexigenic peptides in order to regulate food intake and energy expenditure. Many polymorphisms in leptin (lep) and leptin receptor (lepr) genes have been associated with body weight. In particular, G-2548A in the lep promoter and Q223R in lepr variants … …American Journal of Agricultural and Biological Sciences, Vol. 8, Issue 1 · 12 Feb 2013 · 8,645 accessesView PDF Cite