12 results for “Poor Outcomes”

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Research ArticleOpen accessEvery word in the titleGonadal and Adrenal Abnormalities in Drug Users: Cause or Consequence of Drug Use Behavior and Poor Health OutcomesTodd T. Brown, Amy B. Wisniewski, Adrian S. DobsOpiates and cocaine both have effects on adrenal and gonadal function. Opiates suppress the hypothalamic-pituitary adrenal (HPA) axis, whereas cocaine leads to HPA activation. Opiates also cause gonadal dysfunction in both men and women. During withdrawal from opiates and cocaine, the HPA axis is activated which may reinforce relapse behavior. This review describes these hormonal effects and explores the potential … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 7,049 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleAssociation of Remdesivir with Poor Clinical Outcomes in COVID-19-A Single Center ExperienceRajat Ranka, Arjun, Prasan Kumar Panda et al.The need for an antiviral against COVID-19 prompted clinical trials worldwide and based on initial promising trends, remdesivir was widely used, including in India (compassionate use). Subsequent trials have been conflicting in their results and the utility of the drug has been widely debated. This is a record-based retrospective cohort study in a 1000-bedded government teaching hospital in North India. … …American Journal of Pharmacology and Toxicology, Vol. 17, Issue 1 · 3 Jun 2022 · 7,210 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsOutcomes and Risk Factors Associated with Drug Resistant Tuberculosis in Rural Eastern Cape, South AfricaCarine Bokop Fotso, Sandeep D. Vasaikar, Teke ApalataWith the emergence of Multidrug-Resistant (MDR) and Extensively Drug-Resistant (XDR) strains of Mycobacterium tuberculosis, Tuberculosis (TB) has become an even greater threat in South Africa (SA). The study sought to investigate the resistance pattern of anti-TB drugs in M. tuberculosis as well as to determine the associated risk factors and outcomes for MDR-TB and XDR-TB. A descriptive study was conducted … …American Journal of Infectious Diseases, Vol. 14, Issue 2 · 15 Aug 2018 · 9,536 accessesView PDF Cite

Research ArticleOpen accessIn the abstractRIA-ViT: A Residual Inception Atrous Vision Transformer for Detection of Gallbladder Cancer from CT ImagesAbhishek Sehrawat, Anita Gupta, Vishnupriya, Varun P. GopiGallbladder Cancer (GBC) is a rare but highly aggressive malignancy of the biliary system. In early-stage gallbladder cancer, there are neither overt symptoms nor specific signs. In most patients, it is diagnosed late, resulting in poor outcomes. Even when imaging is available, diagnosing GBC remains difficult because its features overlap with those of non-neoplastic gallbladder pathologies. Furthermore, the overlap between … …Journal of Computer Science, Vol. 22, Issue 10 · 6 Oct 2026 · 413 accessesView PDF Cite

Research ArticleOpen accessIn the abstractBrain Tumor Segmentation and Classification Using HardNet Transformer With Gated Recurrent Unit ModelSaida D, Srinivas Adepu, Thade Lakshmi Devi et al.The uncontrolled growth of brain tumor cells presents a severe health risk, making early diagnosis and accurate classification essential for improving treatment outcomes. However, the existing approaches used for segmentation fail to delineate the tumor regions accurately due to a lack of global contextual information of brain tumors, resulting in poor classification performance. To overcome this limitation, this research proposes … …Journal of Computer Science, Vol. 22, Issue 9 · 26 Sep 2026 · 630 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAn Occlusion Aware Facial Expression Recognition Model Using Fitness Based Cheetah Optimizer and Adaptive Multi-Scale ViT-CNN With Attention MechanismA. Reddy Prasad, A. RajeshAs a highly nuanced aspect of human communication, facial expression recognition presents a computationally complex problem, making it a prominent area of research in computer vision and affective computing. Problems like poor image quality, occlusions, inconsistent illumination, and head attitude changes are frequently observed in images taken from unstructured sources such as the internet that affect the accuracy of facial … …Journal of Computer Science, Vol. 21, Issue 12 · 29 Jan 2026 · 1,962 accessesView PDF Cite

Research ArticleOpen accessIn the abstractA Designing Framework for Ant Colony Algorithm for Managing Cognitive InsomniaRoqia Rateb, Amal Shorman, Ahmad Sami Al-Shamayleh et al.Insomnia, a condition characterized by poor sleep quality, significantly impacts cognitive function, mood, and overall well-being. Traditional treatments like medication and psychological therapies, while effective, often come with limitations such as high costs and limited scalability. This study addresses these challenges by proposing an Ant Colony Optimization (ACO) algorithm-based approach to create a dynamic support network for individuals suffering from … …Journal of Computer Science, Vol. 21, Issue 7 · 7 Jul 2025 · 3,518 accessesView PDF Cite

Research ArticleOpen accessIn the abstractGlobal Test for Superiority and Non-Inferiority Trials with Functional Endpoints DataArsene Brunelle Sandie, Jules Brice Tchatchueng-Mbougua, Anthony WanjoyaThe global two-sided test for functional means difference got much attention in the literary works. While the global one-sided test for functional means difference has not been studied. However, that could have some applications and implications for longitudinal trials or trials with functional data outcomes. This work introduced superiority and noninferiority hypothesis tests for functional data outcomes, which were viewed … …Current Research in Biostatistics, Vol. 9, Issue 1 · 8 Jul 2019 · 12,656 accessesView PDF Cite

Literature ReviewOpen accessIn the abstractSocio-Economic Inequalities and their Impact on Health in PakistanSana Sehar VincentThis article critically reviews published literature on the relationship between socioeconomic inequalities and health outcomes in Pakistan. Studies are systematically assessed in terms to find the relationship between the social, economic, political and biological determinants to health. The studies shown that the genetical abnormalities, malnutrition and terrorism have significantly affected the quality of life. Moreover, international relations and the national … …International Journal of Research in Nursing, Vol. 7, Issue 1 · 23 Jul 2016 · 8,811 accessesView PDF Cite

Research ArticleOpen accessIn the abstractPhyllanthus Amarus Facilitates the Recovery of Peripheral Nerve after InjuryPanakpaporn Wannannond, Jintanaporn Wattanathorn, Supaporn Muchimapura et al.Problem statement: Peripheral nerve injuries are associated with morbidity and outcomes of peripheral nerve repair are poor. Moreover, it can subsequently leads to economic or social disability. Recent findings have shown that oxidative stress plays an important role on the functional recovery retardation of peripheral nerve. However, the impairment mentioned earlier is counteracted by antioxidant. Therefore, this study was carried … …American Journal of Applied Sciences, Vol. 9, Issue 7 · 10 May 2012 · 7,098 accessesView PDF Cite