Research ArticleOpen accessIn the keywordsPreparation and Properties of Copolyanhydrides Based on 2-Hexadecylsuccinic Acid and Sebacic AcidYousef Hamdan, Xiangmei Jiang, Kaixun Huang, Kaichao YuPoly(2-hexadecylsuccinic acid-sebacic acid) (P(HSA-SA)) copolymers have been prepared by melt polycondensation. The copolymers were characterized by FT-IR, 1HNMR, gel permeation chromatography (GPC), differential scanning calorimetry (DSC) and thermal gravimetric analysis (TGA). In vitro studies showed that all our prepared copolymers are degradable in phosphate buffer at 37°C. The release profiles of hydrophilic model drug, ciprofloxcin hydrochloride, from the copolymers, follow … …American Journal of Applied Sciences, Vol. 4, Issue 3 · 31 Mar 2007 · 7,427 accessesView PDFCite