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4 results for “Plasmodium berghei”
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Research ArticleOpen accessIn the keywordsIn Vivo Anti-malarial Tests of Nigella sativa (Black Seed) Different ExtractsH.A.A. Abdulelah, B.A.H. Zainal-AbidinNigella sativa (black seed) seeds have been used as a traditional medicine for the treatment of a variety of sicknesses including parasitic diseases. Intraperitoneal and oral administrations of ethanol, chloroform and aqueous seed extracts (50, 100, 200 and 400 µL kg-1) of N. sativa, were screened in the 4-day suppressive assays for their anti-malarial properties against Plasmodium berghei in mice. … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 2 · 30 Jun 2007 · 8,495 accessesView PDFCite
Research ArticleOpen accessIn the abstractIN VIVO ANTIPLASMODIAL ACTIVITY AND ACUTE TOXICITY OF STANDARDIZED EXTRACT OF EURYCOMA LONGIFOLIA JACK. ROOT TRADITIONALLY USED TO TREAT MALARIAEti Nurwening Sholikhah, Mahardika Agus Wijayanti, MustofaA series of studies has been conducted to prove the Eurycoma longifolia Jack. root as an antimalarial. However, the in vivo antiplasmodial activity of E. longifolia Jack. root standardized extract and its lethal dose 50% (LD50) values is unknown. In vivo antiplasmodial activity was conducted on Plasmodium berghei infected Swiss mice as malaria model with 4-day suppression methods. Sixty mice … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 27 Dec 2013 · 7,732 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Antimalaria Activity and Acute Toxicity of Xetospongia spSyamsudin Abdillah, Rahmatul Wahida Ahmad, Yatnita Parama Cita, Noriah Mohd NoorWe investigated the in vivo activity of extract of Xetospongia sp against Plasmodium berghei Strain ANKA and acute toxicity in mice. The ethanolic extracts of the Xetospongia sp (50-400 mg kg-1 day) were screened for blood schizonticidal against P. berghei strain ANKA in mice during early and established infections. Acute toxicity of extracts of Xetospongia sp at the dose 5000 … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 2 · 2 Sep 2013 · 7,796 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunomodulatory and In vivo Antiplasmodial Activities of Propolis ExtractsSyamsudin, Rita Marleta Dewi, KusmardiProblem statement: Malaria caused by various species of prozoan parasites, Plasmodium. The exact mechanism of humoral immunity in eliminating Plasmodium is not completely understood. However, an antimalarial antibody is strongly suspected to play important role in immunity. The purpose of this research was to evaluate the immunomodulator and antiplasmodial activities of Indonesian propolis extracts. Approach: Thirty male BALB/c mice weighing … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 3 · 30 Sep 2009 · 7,801 accessesView PDFCite