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59 results for “Peripheral Blood”
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Research ArticleOpen accessPhrase in the titleTHE IMMUNOMODULATORY EFFECTS OF PROBIOTIC BACTERIA ON PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS) OF ALLERGIC PATIENTSSomaya M. El Sheikh, Mona A.M. Shalaby, Raghda A. Hafez et al.Allergic diseases represent major health burden. An allergic reaction is characterized by a disrupted T- helper 1⁄T-helper 2 balance toward a preferential allergen specifically induced TH2 cytokine profile, causing allergic inflammation Probiotic bacteria have various benificial effects in many pathologic situation. Studies have shown that the bacteria present in the intestinal micro flora play a role in the TH1/TH2 balance … …American Journal of Immunology, Vol. 10, Issue 3 · 10 Sep 2014 · 8,273 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleGene Expression Profiling of Toll-Like Receptor 4 and 5 in Peripheral Blood Mononuclear Cells of Patients with Systemic SclerosisSimin Almasi, Saeed Aslani, Hadi Poormoghim et al.The Toll-Like Receptor (TLR) family is appeared to be expressed in many cell types in the immune system and plays a role in the pathogenesis of various autoimmune diseases. The expression profile and role of TLRs in Systemic Sclerosis (SSc) have been partly explained. It is aimed through this investigation to evaluate the expression pattern of TLR 4 and 5 … …American Journal of Immunology, Vol. 12, Issue 1 · 17 Mar 2016 · 7,049 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleMELATONIN PROTECTS THE INTEGRITY OF GASTRIC STRUCTURE FROM A STERILE TISSUE INJURY AND AUGMENTS BOTH MONONUCLEAR AND POLYMORPHONUCLEAR PERIPHERAL BLOOD CELLS INDUCED BY THE INJURY IN WISTAR ALBINO RATSBahjat Al-AniPeptic ulcer is a common upper gastrointestinal disease that remains a major public health problem. Gastric ulceration caused by Nonsteroidal Anti-Inflammatory Drugs (NSAID), stress and alcohol are the common causes of gastric ulcer formation in humans following helicobacter pylori bacterial infection of the stomach. The neurohormone, melatonin was reported to protect against NSAID- and stress-induced gastric lesions. We sought to … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 2 · 17 Mar 2014 · 7,227 accessesView PDFCite
Research ArticleOpen accessPhrase in the titlePeripheral Blood Leukocyte Production of BDNF following Mitogen Stimulation in Early Onset and Regressive AutismAmanda Enstrom, Charity Onore, Angela Tarver et al.Brain-derived neurotrophic factor (BDNF) is critical for neuronal differentiation and synaptic development. BDNF is also implicated in the development of psychological disorders including depression, bipolar disorder and schizophrenia. Previously, elevated BDNF levels were observed in neonatal blood samples from infants who were later diagnosed with autism when compared with children who developed normally, suggesting that BDNF may be involved in … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 8,525 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleIn vitro Effects of Beet Root Juice on Stimulated and Unstimulated Peripheral Blood Mononuclear CellsChristiana Winkler, Barbara Wirleitner, Katharina Schroecksnadel et al.Intake of fruits and vegetables rich in antioxidants is suggested to reduce the incidence of cancer and coronary heart disease in humans. Exceptional antioxidant activity of beet root extracts has been reported. Likewise in animal models, e.g., extracts of red beetroot Beta vulgaris var. rubra revealed significant tumor inhibitory effects. Red beetroot concentrate is universally permitted as a food ingredient. … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 4 · 31 Dec 2005 · 9,522 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleEvidences of Apoptosis in Hepatitis C Virus-Infected Hepatocytes and Peripheral Blood Monocuclear Cells in the Absence of Liver InjuryViviana Falcón, Nelson Acosta-Rivero, Mineko Shibayama et al.Understanding the mechanism of Hepatitis C Virus (HCV) pathogenesis is an important part of HCV research. In this study, the presence of apoptosis in HCV-infected liver and Peripheral Blood Mononuclear Cells (PBMC) from patients positive for anti-HCV antibodies and negative for serum HCV-RNA was investigated. The samples obtained from 21 patients were studied by in situ Hybridization (ISH), Immunofluorescence, TUNEL … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 6,975 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleEvidences of Hepatitis C Virus Replication in Hepatocytes and Peripheral Blood Monocuclear Cells from Patients Negative for Viral RNA in SerumViviana Falcón, Nelson Acosta-Rivero, Mineko Shibayama et al.In this study, we examined the expression of hepatitis C virus (HCV) components in hepatocytes and peripheral blood mononuclear cells (PBMC) from patients positive for anti-HCV antibodies and negative for serum HCV-RNA. The samples obtained from 25 randomly selected patients (13 of 25 patients showed no histological evidences of chronic hepatitis and had normal serum ALAT and GGTP levels) were … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 7,164 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleExtracts of Pumpkin (Cucurbita pepo L.) Seeds Suppress Stimulated Peripheral Blood Mononuclear Cells in vitroChristiana Winkler, Barbara Wirleitner, Katharaina Schroecksnadel et al.In the traditional medicine in North America and Mexico, pumpkin seeds have been used as an anthelmintic agent and for supportive treatment in functional disorders of the bladder. Also anti-inflammatory and cardioprotective activity of pumpkin seeds is discussed. Three different extracts of pumpkin seeds were prepared and effects were investigated in unstimulated human peripheral blood mononuclear cells and in cells … …American Journal of Immunology, Vol. 1, Issue 1 · 31 Mar 2005 · 10,711 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleAnalysis of Phenolic Content and Antioxidant Properties of Selected Cowpea Varieties Tested in Bovine Peripheral BloodSarah Adjei-Fremah, Louis EN Jackai, Mulumebet WorkuCowpea is an important grain legume with a dual purpose function as a food and feed resource. Cowpea contains phenolic compounds that are beneficial to human and animal health. We evaluated the phenolic content, condensed tannin content and antioxidant capacities of methanol extracts of seed and leaf of seven varieties commonly used in food and animal feed. The total phenolic … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 4 · 19 Dec 2015 · 7,870 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleThe Flavonoid, Quercetin, Inhibits HIV-1 Infection in Normal Peripheral Blood Mononuclear CellsMadhavan P.N. Nair, Zainulabedin M. Saiyed, Nimisha H. Gandhi, C. N. RamchandProblem statement: Flavonoids and related polyphenols, have been known to possess cardioprotective, anti-tumor, anti-inflammatory, anti-allergic and anti-viral activities. Previous studies have shown that flavonoid, quercetin significantly downregulates expression of pro-inflammatory cytokines in cultured cells via modulation of NFκB and p38MAPK signaling pathways. In the current study, we hypothesize that quercetin exerts anti-HIV activity by differential modulation of pro-and anti-inflammatory cytokine … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 12,184 accessesView PDFCite