Research ArticleOpen accessEvery word in the titleEarly Diagnosis of Parkinson's Disease Through Voice Analysis and Machine LearningAmrita Naik, Mohd Sahil Khan, Akhilesh Manoj Saraf et al.Parkinson’s Disease (PD) is a progressive neurological disorder, and its prevalence has increased considerably in recent years. Early and accurate diagnosis plays a crucial role in effective treatment, but identifying the disease in its early stages remains challenging, especially for non-specialist clinicians. This study presents a predictive analytics framework for detecting Parkinson's disease using voice-based features. To improve the diversity … …Journal of Computer Science, Vol. 22, Issue 11 · 9 Oct 2026 · 637 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleFusing CNN Models for Improved Parkinson’s Disease Detection from Handwritten FeaturesSabrina Benredjem, Tahar MekhazniaNeurodegenerative Diseases (NGD) are a group of progressive neurological disorders, including cognitive decline as Alzheimer’s Disease (AD) and Parkinson’s Disease (PD) that result in the progressive loss of neuronal structure or function. This can lead to a variety of symptoms, in this study we are interested in PD one of the neurological diseases that causes the loss of dopamine-producing neurons … …Journal of Computer Science, Vol. 21, Issue 2 · 22 Jan 2025 · 6,306 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDementia in Parkinson's Disease: A Clinical ReviewRenata Teles Vieira, Leonardo Caixeta, Sergio Machado, Marcelo CaixetaProblem statement: Idiopathic Parkinson's Disease (PD) has being increasingly seen as a neuropsychiatric entity and no longer purely neurological, given the frequency and exuberance with which the psychiatric manifestations occurs. Approach: This review will focus on the epidemiology, clinical aspects, differential diagnosis with Alzheimer's Disease (AD) associated with parkinsonism, Dementia with Lewy Bodies (LBD), Progressive Supranuclear Palsy (PSP), Corticobasal Degeneration … …Neuroscience International, Vol. 2, Issue 1 · 23 Nov 2011 · 7,764 accessesView PDFCite
EditorialOpen accessEvery word in the titleBig Data and Parkinson’s Disease - from Understanding of Disease to Personalised MedicineYen F. Tai, Nicola PaveseThe advancement of information technology in recent years has generated a huge amount of datasets in all areas of scientific research. This has led to new opportunities to harness the 'Big Data' to improve our understanding of diseases - from investigating disease mechanisms to monitoring treatment responses. The Big Data approach is a data-driven and often hypothesis-free, way of studying … …Neuroscience International, Vol. 7, Issue 1 · 27 Jul 2016 · 7,755 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEgronomic Fingerprint Scanner Design for People with Motor Neuron DiseasesAbdulkareem Al-Alwani, Majdi BeseisoFingerprint devices have evolved with time for authentication and identification purposes. It is used in generic security and social applications where identification and logging is required when entering that premises. In some circumstances the lag time increases due to increase in human entrees such as at immigration points, airports, random security checkups, attendance loggers. The increase in overall time due … …American Journal of Applied Sciences, Vol. 10, Issue 12 · 28 Oct 2013 · 6,478 accessesView PDFCite
Research ArticleOpen accessIn the author namesA Hybrid Approach to Process Planning: The Urban Traffic Controller ExampleJimoh Falilat Olaitan, Simon Parkinson, Thomas Leo McCluskeyAutomated planning and scheduling are increasingly utilised in solving evsery day planning task. Planning in domains with continuous numeric changes present certain limitations and tremendous challenges to advanced planning algorithms. There are many pertinent examples to the engineering community; however, a case study is provided through the urban traffic controller domain. This paper introduce a novel hybrid approach to state-space … …Journal of Computer Science, Vol. 13, Issue 8 · 23 Aug 2017 · 7,484 accessesView PDFCite
Research ArticleOpen accessIn the abstractReverse Pharmacology-A Paradigm Shift for Drug Discovery and DevelopmentAshok D.B. VaidyaThe current scenario of drug discovery and development is facing a model perturbation, despite significant advances in genomics, proteomics, metabolomics, combinatorial chemistry and high through put assays. There is an urgent need of a paradigm shift in approaches to drug discovery. Natural products of Ayurveda offer a vast potential for novel phytomolecules with clinical activity. In India, Ayurveda is availed … …Current Research in Drug Discovery, Vol. 1, Issue 2 · 26 Jan 2015 · 15,398 accessesView PDFCite
Research ArticleOpen accessIn the abstractTaurine Implicated in Bromocriptine Induced Hallucination: Glycine-Glutamic-Aspartic Implicated in Bromocriptine Induced SchizophreniaAbdulrahim Abu JayyabProblem statement: The literature is reviewed and supports a strong anecdotal relationship between bromocriptine use and psychosis. It is well known that any interference with brain amino acid levels is likely to lead to disorder. Our previous research has shown that bromocriptine produced significant changes in the heart and kidneys amino acid contents. It has been confirmed that the brain … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 1 · 31 Mar 2010 · 8,032 accessesView PDFCite
Research ArticleOpen accessIn the abstractIntrinsically Unstructured Proteins: Potential Targets for Drug DiscoveryPathan Salma, Chintan Chhatbar, Sriram SeshadriProblem statement: The function of a protein is dependent on its three-dimensional structure. However, numerous proteins lacking intrinsic globular 3D structure under physiological conditions had been recognized. These proteins are frequently involved in some of the most critical cellular control mechanisms and it appears that their rapid turnover, aided by their unstructured nature in the unbound state, provides a level … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,578 accessesView PDFCite