3 results for “Optic Neuropathy”

Set a search alert

Research ArticleOpen accessPhrase in the titleOptic Neuropathy: Characteristic Pathology for Identifying Drugs with Potential to Cause Mitochondrial ToxicityConnor Dyer, Katlyn Droke, Ugne Zekonyte, Mariana RoscaDeleterious effects on mitochondria are known to be frequently caused by prescription drugs, however, there is no standard and specific testing by pharmaceutical companies on these effects on mitochondria during drug development. The objective of this study is to determine if cases of optic neuropathy are related to drug-induced mitochondrial toxicity in a way that could be used to predict … …American Journal of Pharmacology and Toxicology, Vol. 18, Issue 1 · 19 Jan 2024 · 8,562 accessesView PDF Cite

Literature ReviewOpen accessIn the abstractThe Effects of Glucocorticoids on Trabecular Meshwork and its Role in GlaucomaAlina GenisPrimary Open-Angle Glaucoma (POAG), an optic neuropathy that is a leading cause of irreversible blindness, has been studied extensively in hopes of better understanding its underlying mechanism. Glucocorticoids (GC) are commonly used to treat inflammatory ocular conditions but are also known to increase the risk of glaucoma by raising Intraocular Pressure (IOP) in susceptible individuals, leading to steroid-induced glaucoma. Based … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 4 · 14 Oct 2015 · 8,219 accessesView PDF Cite

Research ArticleOpen accessIn the abstractPERFORMANCE ANALYSIS OF GRAY LEVEL CO-OCCURRENCE MATRIX TEXTURE FEATURES FOR GLAUCOMA DIAGNOSISSakthivel Karthikeyan, N. RengarajanGlaucoma is a multifactorial optic neuropathy disease characterized by elevated Intra Ocular Pressure (IOP). As the visual loss caused by the disease is irreversible, early detection is essential. Fundus images are used as input and it is preprocessed using histogram equalization. First order features from histogram and second order features from Gray Level Co-occurrence Matrix (GLCM) are extracted from the … …American Journal of Applied Sciences, Vol. 11, Issue 2 · 24 Dec 2013 · 7,326 accessesView PDF Cite