4 results for “Omeprazole”

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Research ArticleOpen accessIn the keywordsDocking and Molecular Dynamics Simulations in Potential Drugs Discovery: An Application to Influenza Virus M2 ProteinMarine E. Bozdaganyan, Philipp S. Orekhov, Nicola L. Bragazzi et al.Molecular docking is a common method for searching new potential drugs. Improvement of the results of docking can be achieved by different ways-one of them is molecular dynamics simulations of protein-ligand complexes. As a model for our research we chose M2 membrane protein from influenza virus. M2 protein is a high selective tetrameric pH-gated proton channel. It was previously shown … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 3 · 11 Nov 2014 · 8,669 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsAnti-Ulcer (Ulcer-Preventive) Activity of Ficus arnottiana Miq. (Moraceae) Leaf Methanolic ExtractMarslin Gregory, K. P. Vithalrao, G. Franklin, V. KalaichelavanProblem statement: In spite of being one of the well-known medicinal plants used in Indian traditional medicine to treat several ailments, studies pertaining to the pharmacological properties of Ficus arnottiana are very scarce. We studied the anti-ulcer activity and acute toxicity of Ficus arnottiana leaf methanolic extract for the first time. Approach: Freshly collected F. arnottiana leaves were dried, powdered … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 3 · 30 Sep 2009 · 9,329 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsGastroprotective Effects of Melastoma malabathricum Aqueous Leaf Extract against Ethanol-Induced Gastric Ulcer Iin RatsFouad Hussain, Mahmood Ameen Abdulla, Suzita Mohd Noor et al.The gastro-protective effects of the aqueous leaf extract of Melastoma malabathricum was investigated against ethanol-induced gastric mucosal injuries in rats. There were four groups of adult sprague dawley rats, consisting of six rats per group. Macroscopically, oral administration of absolute ethanol to rats that had been pre-treated with only distilled water significantly produced extensive lesions of the gastric mucosa. Oral … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 4 · 31 Dec 2008 · 7,774 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Evaluation of Proton Pump Inhibitor Bioactive Fraction DLBS2411 from Cinnamomum burmannii (Nees & T. Nees) in Animal Model of Gastric Ulceration HealingFlorensia Nailufar, Raymond Rubianto TjandrawinataDLBS2411 is a bioactive fraction from Cinnamomum burmannii that is believed to possess anti-ulceration activity. In this study acetic acid was administered to induce gastric ulcer. Rats were divided into six groups: Healthy animals, untreated animals (acetic acid-induced), treatment group of BAF DLBS2411 25 mg kg-1 Body Weight (BW), BAF DLBS2411 50 mg kg-1 BW and positive control group of … …American Journal of Pharmacology and Toxicology, Vol. 12, Issue 4 · 28 Feb 2018 · 9,939 accessesView PDF Cite