5 results for “Neurotoxin”

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Research ArticleOpen accessEvery word in the titleIn Silico Characterization and Motif Election of Neurotoxins from Snake VenomMahmudul Hasan, Ziaul Faruque Joy, Elius Hossain Bhuiyan, Md Shiful IslamSnake venom is a mixture of many biological components. Snakes usually use their venomic armory to tackle different prey and predators in adverse natural world. Among various components of the snake venom, neurotoxins play an important role in exerting effect by blocking the neuromuscular transmission through selective binding to muscle nicotinic Acetyl-Choline Receptors (nAChR). A set of 30 reference protein … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 2 · 2 Mar 2015 · 7,702 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAluminium Chloride Exposure Had No Effects on the Epididymis of Wistar RatsSamuel Adeniyi Ojo, Joseph Olajide Hambolu, Sunday Samuel Adebisi, Adebayo Adekunle BuraimohAluminium is a ubiquitous element and one of the trace elements with moderate toxic effect on living organism. It is generally a recognized neurotoxin that is believed to be at the root cause of Alzheimer’s disease and third most abundant element in the earth’s crust after oxygen and silicon. Traditionally, aluminium has been considered as nontoxic to humans. However, in … …Current Research in Medicine, Vol. 3, Issue 2 · 25 Aug 2012 · 7,453 accessesView PDF Cite

Research ArticleOpen accessIn the abstractS-Allyl-Cysteines Reduce Amelioration of Aluminum Induced Toxicity in RatsSadhana ShrivastavaProblem statement: Aluminum (Al) is a trivalent cation found in its ionic form in most kinds of animal tissues and in natural waters everywhere. Approach: It is a potent neurotoxin and has been associated in the pathogenesis of several clinical disorders including Alzheimer’s disease. Results: The aim of the study was to demonstrate the protective effect of S-Allyl-Cysteines (SAC) against … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 2 · 12 Aug 2011 · 7,748 accessesView PDF Cite

Research ArticleOpen accessIn the abstractCocaine Exposure Results in Formation of Dendritic Varicosity in Rat Primary Hippocampal NeuronsHonghong Yao, Crystal Bethel-Brown, Anil Kumar, Shilpa BuchProblem statement: It has been well documented that drugs of abuse such as cocaine can cause enhanced progression of HIV-Associated Neuropathological Disorders (HAND), the underlying mechanisms mediating these effects remain poorly understood. Approach: In present study, we explored the impact of cocaine exposure (I and 10 μM) on the dendritic beading in rat primary hippocampal neurons. Using the approach of … …American Journal of Infectious Diseases, Vol. 5, Issue 1 · 31 Mar 2009 · 7,889 accessesView PDF Cite

Research ArticleOpen accessIn the abstract5-Hydroxytryptamine Induces Electrogenic Secretion in the Duodenum of Gerbil (Gerbillus cheesmani)Fawzia Y. Al-BaloolThe effect of serosally added 5-hydroxytryptamine (5-HT 100 µM) on the short circuitcurrent (Isc) across duodenum taken from fed, starved (4 days, water ad lib) and undernourished (50% control food intake for 21 days) gerbils (Gerbillus cheesmani) were investigated. The effect of the neurotoxin, tetrodotoxin (TTX 10 µM) and atropine (100µM) on the maximum increase in Isc induced by 5-HT … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 3 · 30 Sep 2007 · 6,383 accessesView PDF Cite