Research ArticleOpen accessIn the keywordsAPPLICATION OF THE MEDIATION ANALYSIS APPROACH TO CANCER PREVENTION TRIALS RELATING TO CANCER SEVERITYYasutaka ChibaIn a cancer prevention trial, an outcome such as cancer severity cannot be evaluated in individuals who do not develop cancer. In such a situation, the principal stratification approach has been applied. Under this approach, the Principal Strata Effect (PSE) has been considered, which is defined as the effect of treatment on the outcome among the subpopulation in which individuals … …Current Research in Biostatistics, Vol. 4, Issue 2 · 6 Jan 2015 · 7,195 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Water Bath Heating on Tannin Content and Quality Improvement Potential of Gambier (Uncaria gambir Roxb.)Daimon Syukri, Bastian Nova, Rina Yenrina et al.Gambir (Uncaria gambir Roxb.) is a source of natural phenolic compounds rich in catechins and tannins and has potential as a sustainable industrial raw material. During heating, phenolic compounds may undergo structural changes, including possible oxidation and polymerization, which can affect gambier quality beyond its catechin content. This study evaluated the effect of indirect heating duration using a water bath … …OnLine Journal of Biological Sciences, Vol. 26, Issue 4 · 23 Sep 2026 · 704 accessesView PDFCite
Review ArticleOpen accessIn the abstractUnraveling the Mechanisms of Plant Structural Defenses against Insect PestsAroni Preya Biswas, Roksana Al Nafiu Insha, Md. Khairul Mazed et al.Plants employ a variety of physical, chemical, and genetic strategies to defend against herbivore attacks. These biochemical defense mechanisms are complex and dynamic, encompassing both direct and indirect responses. Defense-related chemicals, whether constitutive or induced by herbivore damage, significantly influence herbivore feeding behavior, growth, and survival. Plant defense systems impact herbivore nutrition, development, and survival, highlighting the importance of chemical … …OnLine Journal of Biological Sciences, Vol. 25, Issue 1 · 7 Jan 2025 · 5,793 accessesView PDFCite
Research ArticleOpen accessIn the abstractSurvival and Mediation Analysis with Correlated FrailtyUsha S Govindarajulu, Mohsin QadriMany studies have focused on mediation effects, but fewer have focused on these in a time-to-event analysis and even fewer have focused on these effects in a survival model with frailty effects. The purpose of this study was to show unique modeling of correlated frailty effects with mediation and to demonstrate their use through simulations as well as on a … …Current Research in Biostatistics, Vol. 9, Issue 1 · 1 Dec 2019 · 13,005 accessesView PDFCite
EditorialOpen accessIn the abstractRECENT TRENDS AND CHALLENGES OF ENERGY EFFICIENT AND SUSTAINABLE BUILDINGSChiara BedonAccording to several studies (e.g., the Intergovernmental Panel on Climate Change (IPCC, 2014), the US Energy Information Administration (US EIA, 2014), warming of the climate system is unequivocal and mainly derives from greenhouse gas emissions due to human activities. Global Carbon Dioxide (CO2) emissions from fossil fuels, for example, are estimated to be 29% higher in 2035 than they were … …American Journal of Engineering and Applied Sciences, Vol. 7, Issue 3 · 11 Sep 2014 · 8,497 accessesView PDFCite