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9 results for “Naglaa F. Alhusseini”
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Research ArticleOpen accessIn the author namesCpG Oligodeoxynucleotides Debate the Damaging Action of Cisplatin on Immune Cell DNA: A PCR Array Application on Repair Genes ExpressionNaglaa Fathy Alhusseini, Amal Abo El-Fadl, Shabaan Hemada et al.Synthetic Oligodeoxynucleotides (ODN) expressing CpG motifs (CpG-ODN) mimic the immunostimulatory activity of bacterial DNA and are commonly used to activate Toll Like Receptor 9 (TLR9) for therapeutic applications. CpG-ODN can counteract the activity of DNA-damaging chemotherapy and radiation therapy on immune cell and enhance immunity in preclinical mouse models. We hypothesized that these actions of CpG-ODN on immune cells are … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 3 · 27 Jul 2016 · 7,628 accessesView PDFCite
Research ArticleOpen accessIn the author namesTelomere Length Measurement by Quantitative Real-time PCR: A Molecular Marker for Human Age PredictionNaglaa F. Alhusseini, Abdelmonem G. MadbolyThe fact that telomere shortening occurs with aging leads to the hypothesis that a correlation could be made between Telomere Length (TL) and suspect age. This study aimed to assess if TL can be used as an investigational tool to predict human age through developing a formula based on this correlation with accuracy suitable to be applied in forensic practice. … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 1 · 24 Mar 2016 · 8,011 accessesView PDFCite
Research ArticleOpen accessIn the author namesFactors Affecting the Response to Interferon Alpha Therapy in Egyptian HCV PatientsNaglaa F. Alhusseini, Fathy M. Serry, Ashraf A. Kadry, Heba KhairyHepatitis C Virus (HCV) infection is one of the main causes of chronic liver disease worldwide. Egypt has the highest prevalence of Hepatitis C Virus (HCV) in the world, estimated nationally at 14.7%. knowledge of the predictors of Sustained Viral Response (SVR) to Pegylated Interferon (PEG-INF) and Ribavirin (RBV) therapy in patients with chronic hepatitis C is crucial for selecting … …American Journal of Immunology, Vol. 11, Issue 3 · 30 Sep 2015 · 6,620 accessesView PDFCite
Research ArticleOpen accessIn the author namesFactors Those Up Regulate Klotho and Glutathione Peroxidase-1 Gene Expression Improve Renal Function in Rats with Acute Renal FailureFatma E. El-Gendey, Shabaan A. Hemeda, Gamal A. Sosa, Naglaa F. AlhusseiniAcute Renal Failure (ARF) has traditionally been defined as the abrupt and progressive loss of kidney functions resulting in the retention of urea and other nitrogenous waste products associated with interstitial inflammation, tubular injury and increasing Tumor Necrosis Factor (TNF). Mortality in patients with ARF remains high >50% in severely ill patients. Klotho gene is a new anti-aging gene. Genetic … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 3 · 15 Aug 2015 · 7,101 accessesView PDFCite
Research ArticleOpen accessIn the author namesGene Expression of FADS2 mRNA Linked to Intelligence in Exclusively Breast Milk Fed PretermsNaglaa F. Alhusseini, Amal Idris Ali, Azza M.A. Abul-Fadl et al.Breastfeeding is important for brain development and was shown by many studies to result in higher scores Intelligent Quotient (IQ). However, the exact mechanism whereby Breastfeeding influences cognitive development remains unclear. This study aimed to study the expression of genetic code FADS2 linked to the cognitive function in relation to the mode of feeding. The study comprised 30 preterm infants … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 4 · 25 Nov 2014 · 6,858 accessesView PDFCite
Research ArticleOpen accessIn the author namesHepatitis B Virus DNA Can be Amplified Directly From Dried Blood Spot on Filter PaperNaglaa Fathy Alhusseini, Mamdouh Z. Abadeer, Sheref M. El-TaherHepatitis B Virus (HBV) infections represent a major public health problem because of the ability of HBV to cause a chronic carrier state. Even though chronic carriers remain largely asymptomatic, a large number of these individuals subsequently develop cirrhosis and primary hepatocellular carcinomas. Dried Blood Spot (DBS) samples are a simple and inexpensive sampling method, especially useful for blood collection … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 2 · 22 Jun 2012 · 8,461 accessesView PDFCite
Research ArticleOpen accessIn the author namesEffect of Exercise Training on Adiponectin Receptor Expression and Insulin Resistance in Mice Fed a High Fat DietNaglaa Fathy Alhusseini, Nasr Arafat Belacy, Enas Mohammed Kasem, Mona Maher AllamProblem statement: Adiponectin is an adipocyte secreted hormones, exerts its effects via the specific receptors. AdipoR1 and adipoR2 and plays a pivotal role in lipid and glucose metabolism. Approach: We investigated the effect of increased physical activities on insulin resistance and if this effect is modulated through adiponectin receptor expression. Results: We also assessed the effect of High Fat Diet … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 2 · 30 Jun 2010 · 9,956 accessesView PDFCite