3 results for “NMDA Receptor”

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Research ArticleOpen accessPhrase in the titleDifferent Arrangement of Dopamine Receptors/NMDA Receptors Heterocomplexes in the Brain Regions of a Healthy Male, Female and Audiogenic Seizure-Prone Male RatsGigi Tevzadze, Elene Zhuravliova, Natia Okriashvili et al.Differences in the composition and subcellular localization of heteroreceptors in the brain can trigger central nervous system diseases, including epilepsy and autism. Protein-protein interactions between Dopamine Receptors (DRs) and GLUN2A and GLUN2B subunits are critical mechanisms that regulate dopamine and glutamate coordinated signals. These interactions may be involved in the pathophysiological predisposition of epilepsy. We hypothesized that the specificity of … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 2 · 27 Apr 2022 · 6,098 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsCastration and Passive Avoidance Learning Alter the Distribution of N-Methyl D-Aspartate ReceptorSeyed Hassan Mirzaei, Mahnaz Taherianfard, Mina Tadjali, Mahbobeh KohkaloyehIn neurophysiological studies on learning and memory, L-glutamate receptors especially N-Methyl, D-Aspartate glutamate (NMDA) receptors have a major role in different aspect of the learning and memory. Two sites of mammalian brain that show high density of these receptors are CA1 region of hippocampus and Purkinje cell layer of cerebellum. Twenty four Sprague-Dawley rats were used in 4 groups: Control … …Neuroscience International, Vol. 4, Issue 2 · 1 Apr 2014 · 6,773 accessesView PDF Cite

Research ArticleOpen accessIn the abstractPrenatal Exposure to Chronic Ethanol on N Methyl D Aspartate Receptor DistributionM. Taherianfard, B. Geramizadeh, E. Evazi, M. SharifiProblem statement: Effect of chronic exposure to ethanol on NR1 subunit of the NMDA receptor distribution in chick embryo brain chronic ethanol intake leads to the development of dependence on and tolerance to ethanol in both human and animals. The glutamate system plays a major role in mediating ethanol effects on brain and behavior. The aim of the present study … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 4 · 21 Feb 2012 · 7,301 accessesView PDF Cite