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27 articles for “Mutagen”
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Research ArticleOpen accessEvery word in the titleIndications of Potential Toxic/Mutagenic Effects of World Trade Center Dust on Human Lung Cell CulturesConstantino G. Lambroussis, Barbara D. Soares, Sergio Perez et al.Problem statement: Respiratory complications have been linked with exposure to dust particulates after the tragedy of September 11th, 2001 at the World Trade Center (WTC) site. Approach: The purpose of these experiments was to investigate the extent of cellular damage resulting from WTC dust exposure. Results: This research project was conducted with human lung fibroblast cells exposed to WTC dust. … …OnLine Journal of Biological Sciences, Vol. 9, Issue 3 · 30 Sep 2009 · 7,394 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleChemical Mutagenesis for Improvement of Production of a Biologically Active Extracellular Polymeric Substance by Halomonas xianhensis SUR308Jhuma Biswas, Amal K. PaulA moderately halophilic bacterium, Halomonas xianhensis SUR308 (Genbank Accession No. KJ933394) isolated from solar saltern of Surala, Odisha, India was found to produce significant amount of a biologically active extracellular polymeric substances (EPS). Under optimized cultural conditions, the strain was able to produce 7.05 g L-1 of EPS after 8 days of incubation under shake culture. To enhance the EPS … …Current Research in Microbiology, Vol. 7, Issue 1 · 1 Apr 2016 · 15,918 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMutagenic Screening of Crude Oil Fractions Using Modified Ames Test and Allium cepa (Linn) AssayOlufunsho Awodele, Alade Akintonwa, Sunday O. Olayemi et al.Problem statement: Crude oil which may be broadly characterized as paraffinic or naphthenic is a complex mixture of alkanes, cycloalkanes and aromatic hydrocarbons. About 500,000 workers are employed in crude oil exploration and production worldwide. There have been reports of occupational exposure during drilling, pumping and transportation of crude oil, including maintenance of equipment used for these processes. Thus, skin … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 1 · 31 Jan 2010 · 8,629 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAssessment of the Mutagenicity of Some Pharmaceutical EffluentsA. Akintonwa, O. Awodele, A. T. Olofinnade et al.Problem statement: The pharmaceutical industry is a major contributor to industrial wastes globally. Effluents from this industry are usually discharged into the environment and when not properly handled and disposed, they affect both human health and the environment. Approach: This study evaluated the mutagenic potentials of effluents from six pharmaceutical companies in the Lagos province of Nigeria using modified Ames … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 7,509 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIsolation and Mutagenesis of Streptokinase Producing BacteriaThaer Taleb Abed Abdelghani, Adinarayana Kunamneni, Poluri EllaiahOf 103 β-haemolytic Streptococci (with haemolytic activity) in total were isolated from different samples of blood and biomass from infected throat, 47 isolates exhibited streptokinase (SK) activity. T3, identified as a new variant of Streptococcus equisimilis, was found to be excellent SK producer in submerged fermentation and was selected for strain improvement studies. This strain was mutagenized by UV and … …American Journal of Immunology, Vol. 1, Issue 4 · 31 Dec 2005 · 7,789 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDetermination of the Mutagenicity of 2-aminoanthracene Using Chicken Hepatic S-9 FractionVladimir A. Chistyakov, Alexander V. Usatov, Aleksander I. Klimenko et al.The abundance of potential genotoxins makes it necessary to improve microbial test systems that allow to identify these substances quickly. At the same time, the methodology of metabolic activation of promutagens in vitro is very important. Microsomal preparations of rodents, which are generally used for that, have significant disadvantages associated with the potential health risks of the inducers of the … …OnLine Journal of Biological Sciences, Vol. 18, Issue 4 · 16 Nov 2018 · 7,192 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleProbing the Substrate Specificity and Intersubunit Interactions of Brevundimonas Diminuta Glutaryl Acylase with Site-Directed MutagenesisMichael Eldarov, Anna Lyashenko, Tatyana Sherbakova et al.Glutaryl-7-ACA acylases (GLA) are industrial enzymes widely used for the production of 7-aminocepahlosporanic acid (7-ACA)-the starting compound for manufacturing of semisynthetic cephalosporin antibiotics. Generation of mutant GLA's with increased activity and stability, capability for single-step conversion of cephalosporin C (CPC) directly to 7-ACA is a promising route to improve the current biocatalytic technologies. In this study GLA from Brevundimonas diminuta … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 3 · 12 Nov 2014 · 8,160 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEnhanced Production of Extracellular Alkaline Lipase by an Improved Strain of Pseudomonas aeruginosa MTCC 10,055Deepali Bisht, Santosh Kumar Yadav, Nandan Singh DarmwalProblem statement: Lipases are industrially important enzymes having applications in numerous industries. For easy commercialization it is necessary to produce lipases at industrial level which could be achieved by strain improvement and medium formulation. Approach: In the present study strain improvement of Pseudomonas aeruginosa MTCC 10,055 was done by chemical mutagenesis using mutagen 4-nitroquinoline1-oxide for alkaline lipase production. Different fermentation … …American Journal of Applied Sciences, Vol. 9, Issue 2 · 24 Nov 2011 · 8,760 accessesView PDFCite
Research ArticleOpen accessIn the keywordsStudy on the Polyploidy Induction of Herbicides on Hengshan Astragalus MembranaceusJianxia Liu, Yanmao Gao, Lizhen Liu et al.Studying medicinal polyploid plants is of great significance for the cultivation of traditional Chinese medicine varieties and the extraction of active ingredients. The polyploidization of A. membranaceus (Astragalus membranaceus) was induced using two treatment methods: oryzalin and pendimethalin as mutagens. The results showed that in the same method, the induction effect of polyploidy was affected by the concentration of reagents … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 1 · 14 Apr 2026 · 1,535 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Removal of Methyl Red from Aqueous Solutions Using Banana Pseudostem FibersMas Rosemal H. Mas Haris, Kathiresan SathasivamProblem statement: The aim of this study was to investigate the removal of methyl red, a mutagenic monoazo dye, from various aqueous solutions using banana pseudostem fibers of the size 212-350 micron. Approach: The parameters studied were the effect of pH, amount of adsorbent, contact time, concentration of adsorbate and agitation speed. Results: Equilibrium data were fitted to the Langmuir … …American Journal of Applied Sciences, Vol. 6, Issue 9 · 30 Sep 2009 · 8,298 accessesView PDFCite