Research ArticleOpen accessPhrase in the titleA Selection-based MCL Clustering Algorithm for Motif DiscoveryChunxiao Sun, Zhiyong Zhang, Jinglei Tang, Shuai LiuAs motif discovery plays an important role in the understanding of the relationship of gene regulation, this paper puts forward a selection-based MCL clustering refinement algorithm (SMCLR) aiming at solving the planted (l, d) motif search (PMS) problem. Firstly, we divide the DNA dataset into different subsets through selection of reference sequence and screen parts of eligible subsets by setting … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 4 · 1 Jan 2019 · 8,827 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleGenetic Algorithm Based Probabilistic Motif Discovery in Unaligned Biological SequencesM. Hemalatha, K. VivekanandanFinding motif in biosequences is the most important primitive operation in computational biology. There are many computational requirements for a motif discovery algorithm such as computer memory space requirement and computational complexity. To overcome the complexity of motif discovery, we propose an alternative solution integrating genetic algorithm and Fuzzy Art machine learning approaches for eliminating multiple sequence alignment process. Problem … …Journal of Computer Science, Vol. 4, Issue 8 · 31 Aug 2008 · 6,729 accessesView PDFCite