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Research ArticleOpen accessIn the keywordsEfficient Production of Glycosylated and Non-Glycosylated Mycobacterium tuberculosis Antigen 85B Fused to PVX Coat Protein in Nicotiana benthamiana PlantsPablo A. González, Franco D. Puccio, Alicia M. ZeladaThe development of alternative subunit based-vaccines against tuberculosis is necessary due to variable efficiency and some security concerns of the BCG vaccine. The aim of this work was evaluate the production of the Mycobacterium tuberculosis Ag85B antigen fused to Potato Virus X Coat Protein (PVX-CP) by transient expression in Nicotiana benthamiana for subunit-based tuberculosis vaccine formulation. A codon-optimized M. tuberculosis … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 4 · 13 Nov 2018 · 9,976 accessesView PDF Cite

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