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19 results for “Metabolic syndrome”
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Research ArticleOpen accessPhrase in the titleCoronary Heart Disease (CHD) Risk Factors and Metabolic Syndrome in HIV-Positive Drug Users in MiamiMarianna K Baum, Carlin Rafie, Shenghan Lai et al.The frequency of coronary heart disease (CHD) is increasing among HIV seropositive persons. This phenomenon may be related to HIV disease itself, the use of antiretroviral medications and increased length of survival, or the synergism of these factors. In this study we have calculated the 10-year CHD risk estimate and the prevalence of metabolic syndrome in a cohort of 118 … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,989 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleLeptin and Adiponectin in the HIV Associated Metabolic Syndrome: Physiologic and Therapeutic ImplicationsSotirios Tsiodras, Christos MantzorosLeptin and adiponectin represent two newly discovered adipose tissue derived hormones with important roles in energy homeostasis and insulin resistance. Their interrelations with the manifestations of the HIV associated metabolic syndrome and specific somatomorphic changes i.e. fat redistribution is reviewed. A synopsis of published studies is presented and the potential role of leptin and adiponectin is discussed. We have described … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 10,099 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleWeight Gain, Conditioning and Metabolic Syndrome: A Sled Dog ModelAline Collin, Shannon Jimmie, Arleigh Reynolds et al.Type II Diabetes (T2D) and insulin resistance are growing national health concerns. Obesity is a risk factor for developing T2D and is associated with chronic and systemic inflammation. Exercise on the other hand has been shown to improve glucose metabolism and insulin sensitivity. We investigated the effects of conditioning and weight gain on adiponectin, tumor necrosis factor and glycosylated hemoglobin, … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 3 · 18 Aug 2019 · 7,728 accessesView PDFCite
Research ArticleOpen accessIn the keywordsA Sled Dog Model for Positive Health Effects of Weight Management and ExerciseLaura Falkenstein, Scott Jerome et al.Obesity is a significant risk factor for metabolic syndrome and type II diabetes. Physical activity and/or dietary modification can reduce the incidence of obesity. Marginal fitness levels limit the efficacy of exercise training, and most humans choose from a wide range of dietary strategies to lose weight. Despite these limitations, exercise in the absence of weight loss may offer protective … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 1 · 23 Feb 2023 · 6,151 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAssessment of Cardio-Metabolic Risk Factors among Young Adult FemalesSwati Dhruv, Uma Iyer, Kusum BhattProblem statement: Over the past two decades there has been a striking increase in the number of people with metabolic syndrome in developing countries. The current study was thus undertaken to map the prevalence of Metabolic Syndrome (MS) and to assess the cardio-metabolic risk factors among young adult females (n = 1303) aged 18-26y from four girls hostel of the … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 23 Feb 2012 · 7,874 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAmelioration of Inducible Nitric Oxide Synthase, Insulin like Growth Factor-1 Gene Expression and Insulin Receptor Substrate-1 in Liver Tissue of Insulin Resistant Rats Treated With L-CarnitineHala M. GhanemProblem statement: It has been reported that genes expression (inducible Nitric Oxide (iNOS). Insulin-like Growth Factor-1(IGF-1) have a role in both glucose homeostasis and insulin resistance. The aim of this study was designed to evaluate the amelioration of the iNOS, IGF-1 genes expression as well as IRS-1 in liver tissues of rats fed high fructose diet treated with Lcarnitine. Approach: … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 3 · 30 Sep 2010 · 7,264 accessesView PDFCite
Review ArticleOpen accessIn the keywordsThe Intricate Relationship between Obesity and Type 2 DiabetesAnastasia V. Poznyak, Elizaveta M. Pleshko, Aleksandra S. Utkina et al.The rising prevalence of obesity and type 2 diabetes mellitus (T2DM) has emerged as one of the most pressing global public health challenges, profoundly impacting various demographic groups worldwide. This review synthesizes recent epidemiological data and explores the intricate biochemical mechanisms linking obesity to T2DM. We highlight the multifactorial nature of obesity, characterized by excessive adipose tissue, systemic inflammation, and … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 9 Aug 2026 · 455 accessesView PDFCite
Review ArticleOpen accessIn the keywordsCoenzyme Q10 Supplementation Effect on Systemic DiseasesAya Jabbar HusseinThis review paper aims to examine recent RandomizedClinical Trials (RCTs) and review articles evaluating the role of CoQ10 in themanagement of atherosclerosis, and coronary heart disease, with particularfocus on Statin-Associated Muscle Symptoms (SAMS), chronic heart failure, andthe effect on cardiovascular risk factors. With an evaluation of its impacts onpatients' well‐being, it seeks to outline the existing opportunities for usingCoQ10 in … …American Journal of Pharmacology and Toxicology, Vol. 17, Issue 1 · 20 Oct 2022 · 6,525 accessesView PDFCite
Research ArticleOpen accessIn the keywordsUncommon Toxicologic Profile at Toxic Doses of CPI-613 (an Agent Selectively Alters Tumor Energy Metabolism) in Rats and Minipigs Reflects Novel MechanismClaudia Maturo, King C. Lee, Robert Rodriguez, Robert ShorrProblem statement: CPI-613 is a novel anticancer agent and the toxicological profile has not been assessed. Accordingly, the objective of these studies was to thoroughly evaluate the Toxicokinetic (TK) effects of CPI-613 in rats and to compare the toxicological profile of rats to minipigs to determine if there were differences between the two animal species. Approach: These studies involved assessments … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 4 · 13 Jun 2011 · 9,582 accessesView PDFCite
Research ArticleOpen accessIn the abstractComputational Prediction of Diabetic Nephropathy-Associated Comorbidities and Their Key Genes by Analyzing RNA-Seq DataChaity Paul, Md. Ashiq Uddin, Rupa Dey et al.Diabetic Nephropathy (DN) is a complex health condition that leads to various kidney diseases. According to the World Health Organization, over 2 million deaths have been reported due to diabetes and diabetes related kidney diseases in 2021. And at the recent 78th World Health Assembly, chronic kidney disease was reported to be one of the most common diabetes-related complications, and … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 19 May 2026 · 1,667 accessesView PDFCite