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16 articles for “Metabolic Profile”
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Research ArticleOpen accessIn the keywordsRELATIONSHIPS AMONG INDICATORS OF FITNESS, FATNESS AND CARDIOVASCULAR DISEASE RISK FACTORS IN ADOLESCENTSRobert Malina, Stephen-Mark Cooper, John Young et al.In adults, fatness and low cardiorespiratory fitness are associated with a higher prevalence of chronic disease risk and mortality. The association between measures of physical fitness and fatness upon cardiovascular risk in youth, however, is less clear. The effects of adiposity and physical fitness upon cardiovascular disease risk factors in youth are receiving increasing attention but studies that have examined … …OnLine Journal of Biological Sciences, Vol. 12, Issue 3 · 7 Aug 2012 · 8,114 accessesView PDFCite
Research ArticleOpen accessIn the keywordsUncommon Toxicologic Profile at Toxic Doses of CPI-613 (an Agent Selectively Alters Tumor Energy Metabolism) in Rats and Minipigs Reflects Novel MechanismClaudia Maturo, King C. Lee, Robert Rodriguez, Robert ShorrProblem statement: CPI-613 is a novel anticancer agent and the toxicological profile has not been assessed. Accordingly, the objective of these studies was to thoroughly evaluate the Toxicokinetic (TK) effects of CPI-613 in rats and to compare the toxicological profile of rats to minipigs to determine if there were differences between the two animal species. Approach: These studies involved assessments … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 4 · 13 Jun 2011 · 9,582 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Aerobic Exercise on PPAR-γ Expression in Adipose Tissue and RT-PCR Detection AnalysisXiaodong Zhan, Chenguang Bi, Jie WeiThis study aimed to examine the effect of organized aerobic exercise on the expression level of Peroxisome Proliferator-Activated Receptor gamma (PPAR-γ) gene in adipose tissue by performing digital variant of RT-PCR, Droplet Digital PCR (ddPCR) which is a highly sensitive method for counting the gene copy numbers. The proposed scheme consists of three-stage analytical procedure, namely, Subphase I Controlled Aerobic … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 3 · 29 Sep 2026 · 580 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Vitamin D Deficiency on Cardio Metabolic Ageing in Middle Aged Adults in India: A Comparative AnalysisSumit Kumar, Adithi K, Shailaja S MoodithayaAdvancing age is accompanied by a gradual deterioration in physiological function, resulting in an increased risk of chronic diseases and early mortality. Growing evidence suggests that inadequate vitamin D status may be associated with unfavourable metabolic and cardiovascular alterations. Nevertheless, information regarding the association of vitamin D status with integrated cardio-metabolic biomarkers of ageing in middle-aged adults is currently limited. … …OnLine Journal of Biological Sciences, Vol. 26, Issue 3 · 3 Sep 2026 · 732 accessesView PDFCite
Research ArticleOpen accessIn the abstractExploring the Role of Vitamin B12 as an Anti-atherogenic and Anti-inflammatory Agent in Apparently Healthy Adults With Hypovitaminosis DShravan Ajith Panchwadkar, Sudha Kuthethur, Sowndarya Kollampare, Neelam Manjunath PawarVitamin B12 deficiency is associated with metabolic changes like methyl malonic acidemia and hyperhomocystinemia eventually leading to atherosclerosis. Dyslipidemia and vitamin D (vit D) deficiency are independent risk factors of CVD. This study aims to explore the interrelationship between inflammatory markers, adverse lipid profile and vitamin B12 in hypovitaminosis D. Since, atherosclerosis is an inflammatory condition we have investigated CRP … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 11 Jul 2025 · 3,326 accessesView PDFCite
Review ArticleOpen accessIn the abstractCardiolipin in Pathology: Implications in AtherosclerosisAnastasia Vladimirovna Poznyak, Vasily Nikolaevich Sukhorukov, Anton Yuvenalievich Postnov et al.Mitochondria are cell organelles whose main role is to generate the energy needed for cell biochemical reactions via oxidative phosphorylation. Cardiolipin is a phospholipid that is present in the inner mitochondrial membrane and other energy-transducing membranes. Mitochondrial structure largely depends on cardiolipin, as it is involved in the biogenesis of mitochondrial cristae, folds in the inner mitochondrial membrane designed to … …OnLine Journal of Biological Sciences, Vol. 23, Issue 4 · 23 Sep 2023 · 4,792 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDFCite
Research ArticleOpen accessIn the abstractMetabolite Profiles of Arsenic Tolerant Plants Regenerated from Stem Calli of Andrographis paniculata (Burm.f.) Nees using HPLC and 1D 1H NMRJ. Vijayakumar, P. Ponmanickam, P. Samuel et al.In vitro culture provide a suitable condition for regeneration of arsenic tolerant plants from stem calli of Andrographis paniculata (Burm.f.) Nees. The regenerated plants could be valuable material applicable to soil remediation. In vitro culture of stem explants on MS basal salts, 3.0% sucrose, 0.8% agar medium fortified with various concentrations of As2O3 (0.0-9.0 µM) along with NAA (3.5 mg … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 4 · 27 Oct 2017 · 7,865 accessesView PDFCite
Research ArticleOpen accessIn the abstractMetabolic Features of Heart Failure with Different EtiologyOleynikov Dmitrij ArkadievichDilated Cardiomyopathy (DCM) and Chronical Degenerative Valvular Disease (CDVD) are very common in dogs nowadays. However, due to modern level in oncology we can meet chemotherapy-induced cardiomyopathies more often. We have lack of information about pathogenic mechanisms underlying Doxorubicin-induced Cardiomyopathy (DoxCM) and features differentiating it from CDVD and DCM. In this study we investigate several metabolic features of doxorubicin-induced cardiomyopathy, … …American Journal of Animal and Veterinary Sciences, Vol. 12, Issue 1 · 9 Mar 2017 · 7,172 accessesView PDFCite
Research ArticleOpen accessIn the abstractNutritional and Fatty Acids Profile Analyses of Commonly Consumed Fresh Water Fish Species in PakistanAhsan Hameed, Syed Ammar Hussain, Muhammed Asim Shabbir et al.The aim of this study is to evaluate nutritional value of selected commonly consumed fresh water fish species of Pakistan. Proximate composition and fatty acids profile of mostly consumed fresh water fish species of Pakistan namely Balm or Baam (Anguilla anguilla), Sole (Channa marulius), Damra (Labeo rohita) and Malhi (Wallago atto) were analysed. Proximate composition data showed a significant difference … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 1 · 31 Jan 2017 · 9,515 accessesView PDFCite