3 results for “Martin A. Turman”

Research ArticleOpen accessIn the author namesTacrolimus Dosing Challenges in an African American ChildTeresa V. Lewis, Tracy M. Hagemann, Martin A. TurmanIt has been suggested that African Americans have decreased effectiveness with immunosuppressive drugs. Data regarding the pharmacokinetics of tacrolimus in African Americans are limited. We present the case of an African American child in whom management of nephrotic syndrome caused by focal segmental glomerulosclerosis has been challenging due to unpredictable patient specific pharmacokinetic disposition of tacrolimus. Racial differences have been … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 3 · 30 Sep 2007 · 6,708 accessesView PDF Cite

Research ArticleOpen accessIn the author namesRapamycin Inhibits Cystogenesis by Cystic Epithelial Cells Derived from Human Autosomal Dominant Polycystic KidneysGerard Elberg, Teresa V. Lewis, Lijuan Chen, Martin A. TurmanAutosomal dominant polycystic kidney disease (ADPKD) is one of the most common genetic disorders and carries a high health burden since it progresses to renal failure in half of the afflicted individuals by the 6th decade of life. Currently, there is no effective treatment to slow the progression of ADPKD. Rapamycin, a drug most commonly used as an immunosuppressive agent … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2006 · 7,101 accessesView PDF Cite