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121 articles for “Male Rats”
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Research ArticleOpen accessPhrase in the titleImpact of Coriander Seeds Extract Against Thyroidectomy Induced Testicular Damage and DNA Replication in Male RatsAzhar Azher Alankooshi, Ahmed F. Hasan et al.An important target organ for thyroid hormone activity is the testis and hypo or hyperthyroidism causes noticeable alterations in testicular function. This study aimed to investigate the therapeutic effect of Coriander Seeds Extract (CSE) against thyroidectomy induced toxicity, oxidative stress, injury, and proliferation in male testes rats. 40 male rats were equally divided into 4 groups [Gp1, control; Gp2, CSE; … …OnLine Journal of Biological Sciences, Vol. 23, Issue 2 · 3 Apr 2023 · 6,611 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleDifferent Arrangement of Dopamine Receptors/NMDA Receptors Heterocomplexes in the Brain Regions of a Healthy Male, Female and Audiogenic Seizure-Prone Male RatsGigi Tevzadze, Elene Zhuravliova, Natia Okriashvili et al.Differences in the composition and subcellular localization of heteroreceptors in the brain can trigger central nervous system diseases, including epilepsy and autism. Protein-protein interactions between Dopamine Receptors (DRs) and GLUN2A and GLUN2B subunits are critical mechanisms that regulate dopamine and glutamate coordinated signals. These interactions may be involved in the pathophysiological predisposition of epilepsy. We hypothesized that the specificity of … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 2 · 27 Apr 2022 · 6,098 accessesView PDFCite
Research ArticleOpen accessPhrase in the titlePreparation, Identification and Antioxidant Evaluation of Citrullus Colocynthis Root and Fruit Extracts Against Doxorubicin in Male RatsSarah Samir Othman, Gamal M. Hamad, Sabria Abo Zaid Hassan et al.Millions of people are affected by diseases in developing or developed countries. Citrullus colocynthis is a high-antioxidant wildflower, it is healthy to eat and may be used as a source of energy or medication. The goal of this research was to conduct a phytochemical analysis of Citrullus colocynthis fruit extract, which is abundant in Egypt. Different extracts from that plant … …OnLine Journal of Biological Sciences, Vol. 22, Issue 1 · 8 Feb 2022 · 6,243 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleProtective Role of Chichorium intybus Extract Against Renal Toxicity Induced by Magnetite Silver Nanoparticles in Male RatsDoha M. Beltagy, Ehab Tousson, Nabiha I Abdo, Batoul M. IzzularabMagnetite silver nanoparticles (Fe3O4/AgNPs) symbolize a new candidate in several industrial and biological products for their activities, simple preparation and low synthesis costs. Many studies recommended the usage of Fe3O4/AgNPs to overcome lacking biocompatibility of AgNPs inside the body. However, Fe3O4/AgNPs also has toxic effects on kidney tissues. In this study, AgNPs was synthesized on the surface of magnetic nanoparticles … …OnLine Journal of Biological Sciences, Vol. 21, Issue 3 · 15 Sep 2021 · 6,318 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleBiochemical Efficacy of Nigella Sativa Oil and Metformin on Induced Diabetic Male RatsYassmina K. Mahmoud, Sherif Y. Saleh, Abd El Rehim A. El Ghannam, Ibrahim A. IbrahimThis study was carried out to investigate possible beneficial effects of Nigella sativa oil supplementation to diabetic rats. Fifty male Sprague-Dawley rats were randomly divided into five groups (n = 10/group) as follows: group I (normal control), group II (diabetic control), group III (diabetic rats treated with metformin), group IV (diabetic rats treated with metformin and Nigella sativa oil) and … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 24 Dec 2014 · 7,898 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleEffect of Bisphenol a on Passive Avoidance Performance in Male RatsMahnaz Taherianfard, Bita Geramizadeh, Mehrzad Banihashemi et al.Bisphenol A (BPA) is used to manufacture polycarbonate plastic products in resins lining metal cans, in dental sealants and in blends with other types of plastic products. In sharp contrast, there are many published studies that BPA has a wide range of significant adverse effects including structural and neurochemical changes throughout the brain associated with behavioral changes, such as hyperactivity, … …Current Research in Medicine, Vol. 4, Issue 2 · 10 Dec 2013 · 7,222 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleγAminobutyrate B Receptors in Central Amygdaloid and Medial Amygdaloid Nuclei of Amygdala Modulate Aggression in Male RatsMahnaz Taherianfard, Zahed Abdolahi, Hamid Rajaian et al.One neurochemical system most consistently linked with aggression is the GABAergic system. The aim of the present investigation was to examine the effect of injection of baclofen (GABAB agonist) and CGP35348 (GABAB antagonist) in the Central Amygdaloid (CA) and Medial Amygdaloid (MA) nuclei of the amygdala on offensive aggression behavior in the animal model. Sixty six adult male rats weighing … …Neuroscience International, Vol. 3, Issue 1 · 3 Sep 2012 · 7,257 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleScreening Neuropharmacological Activities of Kaempferia parviflora (Krachai Dam) in Healthy Adult Male RatsThaneeya Hawiset, Supaporn Muchimapura, Jintanaporn Wattanathorn, Bungorn SripanidkulchaiProblem statement: Although the global prevalence of psychological disorders is increasing continually, the efficacies of therapeutic strategies are still very limited. Oxidative stress has been implicated in the pathogenesis of psychiatric disorders and substance possessing antioxidant activity can alleviate the mentioned conditions. Therefore, we hypothesized that Kaempferia parviflora, a medicinal plant claimed for nerve tonic, also possessed the neuropharmacological activities … …American Journal of Applied Sciences, Vol. 8, Issue 7 · 24 Jun 2011 · 8,697 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleEvaluation of in vivo Antioxidant and Hepatoprotective Activity of Portulaca oleracea L. against Paracetamol-Induced Liver Toxicity in Male RatsMohamed H. AhmidaProblem statement: Oxidative stress plays a major role in paracetamol induced hepatotoxicity. Portulaca oleracea (P.O.) has been shown to exhibit antioxidant properties. The present study aimed to investigate the effect of P.O. on the oxidative stress in Paracetamol-induced hepatic toxicity in male rats. Approach: Forty male rats were divided into four groups. Group I served as control; Group II Received … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 4 · 13 Jun 2011 · 7,327 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleAntilithiatic Influence of Spirulina on Ethylene Glycol-Induced Nephrolithiasis in Male RatsAtef M. Al-AttarProblem statement: Nephrolithiasis or renal stone disease remains a significant health problem in the adult population. Nephrolithiasis is a recurrent disorder prominent in males. It is significant medical and surgical problem because of incidence, recurrence and severe consequences. The present day medical management of nephrolithiasis is either costly or not without side effects. Invasive procedures for the treatment of nephrolithiasis … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 1 · 31 Mar 2010 · 70,595 accessesView PDFCite