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67 results for “M. tuberculosis”
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Research ArticleOpen accessEvery word in the titleEvaluation of Language Models (LLMs) in the Interpretation of Tuberculosis Concepts: Design of a Virtual Assistant for Clinical Support and Patient EducationMauricio Acevedo-Carrillo, Shirley Fiorella Simbron EspejoTuberculosis (TB) remains a global public health challenge, where access to accurate and up-to-date information is crucial for professionals and patients. This research comparatively evaluated the performance of five language models (LLMs) Med-PaLM 2, GPT-4, MEDITRON-70B, Me-LLaMA, and Clinical Camel in the TB domain and implemented a mobile virtual assistant as a proof-of-concept based on the best-performing model. Clinical accuracy … …Journal of Computer Science, Vol. 22, Issue 9 · 30 Sep 2026 · 491 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleRisk Factors for Bovine Tuberculosis Transmission in Burkina Faso’s Cattle HerdsArouna Zoungrana, Pingdwende Albert Patrick Vokouma, Badjibassa Akounda et al.Bovine tuberculosis is a zoonotic disease, primarily caused by Mycobacterium bovis, that poses a serious threat to both human and animal health. Understanding the risk factors that contribute to its spread is critical for developing effective prevention and control strategies. This cross-sectional study investigated risk factors associated with bovine tuberculosis in cattle herds in Burkina Faso. A structured survey questionnaire … …American Journal of Animal and Veterinary Sciences, Vol. 21, Issue 1 · 11 Apr 2026 · 1,402 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleThe European Wild Boar (Sus scrofa) as a Reservoir of Tuberculosis: Ecological Drivers and Management ImplicationsGiovanna Liguori, Renato Lombardi, Fabio Castagna et al.Bovine tuberculosis (bTB), an infectious disease primarily caused by Mycobacterium bovis and other members of the Mycobacterium tuberculosis complex, represents a significant challenge to both animal and public health. Despite successful control programs in numerous regions, the presence of wildlife reservoirs, notably wild boar (Sus scrofa), impedes complete eradication and sustains disease propagation. bTB prevalence varies across Europe, with higher … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 3 · 16 Nov 2025 · 2,621 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleClassification of X-Ray Images Using Convolutional Neural Network and Automatic Hyper-Parameter Selection to Detect Tuberculosis (TB)Biswaranjan Debata, Rojalina Priyadarshini, Sudhir Kumar Mohapatra, Tarikwa Tesfa BedaneTuberculosis (TB) is a major public health issue in India, contributing significantly to the global burden of respiratory diseases. This study introduces a Convolutional Neural Network (CNN)--based model for the early and cost-effective detection of TB using chest X-ray images. The proposed model, featuring 13 layers and automated hyperparameter selection, classifies images as infected or not infected. It is evaluated … …Journal of Computer Science, Vol. 21, Issue 2 · 21 Jan 2025 · 6,983 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAnalysis of the Utility of MPT64, Drug Susceptibility Testing and Tuberculosis/Nontuberculous Mycobacteria Reverse Transcription Polymerase Chain Reaction for Tuberculosis Diagnosis and Efficiency Compared with Traditional CultureHo Keun Choi, Ga Yeon Kim, Tae Soung Kim, Jae Kyung KimDefining the molecular mechanisms underlying the dormant state of Mycobacterium tuberculosis (MTB) is essential for developing more effective treatments for tuberculosis (TB) infection. We investigated the positivity and resistance rates of TB tests on 6,174 samples referred to a single hospital. Of these, 342 cases (5.5%) were confirmed as positive by acid-fast bacilli staining, 243 cases (71.1%) were detected as … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 4 · 5 Dec 2024 · 4,206 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAnalysis of Interferon-Gamma Release Assay Results for Latent Tuberculosis Infection Diagnosis at a Referral Clinical Laboratory in South KoreaTae Soung Kim, Ga Yeon Kim, Young Ki Lee, Jae Kyung KimThe world health organization states that individuals with Latent Tuberculosis Infection (LTBI) are infected with Tuberculosis (TB) bacteria but do not show symptoms of active disease. However, they are at possibility of developing vigorous TB and potentially transmitting the illness to others. In 2018, South Korea reported a 14.8% positivity rate in LTBI screening, with higher rates observed among older … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 25 Oct 2023 · 6,033 accessesView PDFCite
Case ReportOpen accessEvery word in the titleNon-Specific Interstitial Pneumonia Overlapping Tuberculosis: A Diagnostic Challenge in ElderlyPradeep Chakaravarthy, Divanshee Sharma, Manjunath Totaganti et al.Non-Specific Interstitial Pneumonia (NSIP) is linked to numerous etiologies, including connective tissue diseases, certain drugs, HIV and idiopathic causes. We present a case of an 82-year-old woman with subacute onset shortness of breath as the presenting feature of Non-specific interstitial pneumonia. Chest imaging demonstrated bilateral infiltrates and tentatively diagnosed as NSIP and started on Tyrosine kinase inhibitor - Nintedanib. But … …American Journal of Infectious Diseases, Vol. 17, Issue 4 · 5 Jan 2022 · 6,168 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMycobacterium tuberculosis Complex Mutations in Drug Resistant Clinical Isolates from Southwest MexicoMartínez-Cruz Perla Mónica, Nakamura-López Yuko, Quintero-Hernández Verónica et al.Mutations in target genes have been described in Mycobacterium tuberculosis Complex (MTBc) drug resistant isolates worldwide. In Mexico, not enough information has been reported in this concern. The aim of this study was to characterize mutations related to resistance to first line drugs in MTBc isolates from Oaxaca, Mexico. MTBc isolates were identified in clinical samples from Tuberculosis (TB) patients. … …American Journal of Infectious Diseases, Vol. 17, Issue 4 · 28 Oct 2021 · 6,667 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleGenetic Diversity and Drug Resistance of Mycobacterium tuberculosis Complex Isolates and Nontuberculous Mycobacteria Identification from Presumptive Tuberculosis Cases in Oaxaca, MexicoNakamura-Lopez Yuko, Valencia-Carmona Oscar Daniel, Martinez-Cruz Perla Monica et al.Tuberculosis (TB) is a re-emerging health problem worldwide. In Mexico, information about genetic diversity and drug resistance of Mycobacterium Tuberculosis complex (MTBc) is limited. Samples from 463 Presumptive TB cases were tested for TB by smear, culture and PCR, from which 19.2% were identify as MTBc and 16% as nontuberculous mycobacteria. MTBc isolates were characterized by Large Sequence Polymorphisms (LSPs), … …American Journal of Infectious Diseases, Vol. 16, Issue 1 · 9 Feb 2020 · 7,159 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleStrategies of Tuberculosis–HIV Vaccines Design using Immunoinformatic ApproachAni Fatonah, Ig. Satrio Wicaksono, Usman Sumo Friend TambunanTuberculosis is amongst the highest cause death worldwide. According to WHO, an estimated of more than a million people fell ill with Tuberculosis (TB) in 2016. The resistances of the M. tuberculosis (MTb) bacteria make drugs, not that useful in battle with TB. Vaccination is a better choice to avoid the worst cases of TB. The resistance possessed by MTb … …OnLine Journal of Biological Sciences, Vol. 19, Issue 2 · 10 May 2019 · 7,925 accessesView PDFCite