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19 results for “Lipopolysaccharide”
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Research ArticleOpen accessEvery word in the titleHormonal and Histopathological Alterations in Pituitary Glands and Reproductive Organs of Male and Female Mice Orally Inoculated with Pasteurella Multocida Type B: 2 and its LipopolysaccharidesFaez Firdaus Jesse Abdullah, Lawan Adamu, Abdulnasir Tijjani et al.Oral infections of mice as animal model with Pasteurella multocida type B: 2 and its lipopolysaccharides is liable to cause detrimental alterations in the pituitary glands, which results in disruption of reproductive hormonal levels as well as organ functions in the male and female animals; thereby impeding the fertility of at risk animal population. Therefore, this study was designed to … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 1 · 23 Dec 2014 · 7,554 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAlterations in Interleukin-1β and Interleukin-6 in Mice Inoculated Through the Oral Routes Using Graded Doses of p. Multocida Type b: 2 and its LipopolysaccharideOmar Suwaidan Ali, Lawan Adamu, Faez Firdaus Jesse Abdullah et al.The gram-negative bacterium Pasteurella multocida serotype B: 2 is an important veterinary and opportunistic human pathogen that causes deplorable welfare problems and colossal economic production losses in bovine and other animal species throughout the world. Pasteurella multocida type B: 2 and its LPS are associated with Haemorrhagic Septicaemia (HS) in mice as animal model. Sixty healthy Balb c mice were … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 1 · 22 Dec 2014 · 7,692 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleLemon Pepper Fruit Extract (Zanthoxylum acanthopodium DC.) Suppresses the Expression of Inflammatory Mediators in Lipopolysaccharide-Induced Macrophages In VitroYanti, Theodorus Eko Pramudito, Nerissa Nuriasari, Katarina JulianaProblem statement: Lemon pepper fruits (Zanthoxylum acanthopodium DC.; Rutaceae) have been used as a traditional source against stomach ache by Batak people in North Sumatera province, Indonesia. However, its scientific evidence for treatment of inflammatory disorders particularly gastritis has not been reported. Approach: Here, we investigated the inhibitory effects of Lemon Pepper Fruit Extract (LPFE) against inflammatory biomarkers by conducting … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 4 · 14 Feb 2012 · 9,581 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAnti-Metalloproteinase-9 Activities of Selected Indonesian Zingiberaceae Rhizome Extracts in Lipopolysaccharide-Induced Human Vascular Endothelial Cells In VitroYantiProblem statement: Atherosclerosis is associated with chronic inflammation triggered by bacterial infection that activates the breakdown of extracellular matrix protein by matrix Metalloproteinases (MMPs). Zingiberaceae, a group of tropical food crops grown in Indonesia and other Southeast Asia regions, has been traditionally used for food coloring, seasoning, culinary and medicinal purposes. However, its efficacy as natural vascular protection has not … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 1 · 27 May 2011 · 7,869 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSerological Evaluation of Brucella abortus S99 Lipopolysaccharide Extracted by an Optimized MethodAli Sharifat Salmani, Seyed Davar Siadat, Mohammad Reza Fallahian et al.Problem statement: Brucellosis is a globally found infectious disease and there is no licensed vaccine against human brucellosis. The present study carried-out to evaluate the potency of our modified extracted lipopolysaccharide (LPS) of B. abortus to elicit specific anti-Brucella antibodies in animal model (Rabbit) as a part of a candidate vaccine for brucellosis. Lipopolysaccharide is one of the main virulence … …American Journal of Infectious Diseases, Vol. 5, Issue 1 · 31 Mar 2009 · 9,080 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMicroarray Analysis of Human Vascular Smooth Muscle Cell Responses to Bacterial LipopolysaccharideJoe Minta James, J. Yun, Sandy Der, Shikha RanaAccumulating evidence suggest a causal role of bacterial and viral infections in atherogenesis. Bacterial lipopolysaccharide (LPS) has been shown to stimulate resting vascular smooth muscle cells (SMC) with the production of inflammatory cytokines and modulation of quiescent cells to the proliferative and synthetic phenotype. To comprehensively identify biologically important genes associated with LPS-induced SMC phenotype modulation, we compared the transcriptomes … …American Journal of Immunology, Vol. 3, Issue 2 · 31 Dec 2007 · 6,994 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleBiochemical and Hematological Alterations in Mice Inoculated with Outer Membrane Protein, Lipopolysaccharides and Whole Cells of Pasteurella multocida Type B: 2Faez Firdaus Jesse Abdullah, Lawan Adamu, Abdinasir Yusuf Osman et al.Haemorrhagic septicaemia in cattle and buffaloes is an economically important livestock disease in Asia including Malaysia. Therefore, the aim of this study was to investigate the biochemical and hematological alterations in mice model inoculated with outer membrane protein, lipopolysaccharides and whole cells of Pasteurella multocida type B: 2. Two hundred healthy male mice of eight to ten weeks old were … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 3 · 17 Sep 2013 · 7,316 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleClinical and Reproductive Pathological Changes Associated with Brucella melitensis and its Lipopolysaccharides in Female Mice Via Oral InoculationFaez Firdaus Jesse Abdullah, Lawan Adamu, Nur Hazirah et al.Brucella melitensis (B. melitensis) are Gram-negative, aerobic, facultative intracellular bacteria that cause brucellosis that usually leads to abortion in sheep and goats. Three groups of equal number of 24 healthy female mice were used as animal models. They were orally inoculated with 0.4 mL of phosphate Buffered Saline (PBS-Control group), 0.4 mL of 109 cfu of B. melitensis and 0.4 … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 3 · 30 Aug 2013 · 8,572 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAnalysis of Salmonella enteritidis Outer Membrane Proteins and Lipopolysaccharide Profiles with the Detection of Immune Dominant ProteinsA. Maripandi, Ali A. Al-SalamahProblem statement: Salmonella infection is a serious medical and veterinary problem world-wide and causes great concern in the human health and food safety. Salmonella enteritidis outer membrane proteins and lipopolysaccharide play important role in the virulence and immunological properties of bacteria. Prophylaxis of enterobacterial infection has proven difficult to achieve. Vaccination is an effective tool for the prevention of Salmonella … …American Journal of Immunology, Vol. 6, Issue 1 · 21 Jun 2010 · 9,147 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleProtection against Lipopolysaccharide-induced Death by An Anti-Interleukin-6 Monoclonal AntibodyBailin Liang, Debra Gardner, Don Griswold, Xiao-yu R. SongSepticemia is frequently associated with serious complications and high mortality despite recent advances in treatment with antibacterial agents. Infectious organisms or their soluble products initiate septic shock through a complex cytokine cascade. Lipopolysaccharide (LPS) induced excessive production of inflammatory cytokines is regarded as a model of septic shock. Experiments of LPS-induced excessive cytokine production were conducted in Balb/c mice for … …American Journal of Immunology, Vol. 3, Issue 1 · 30 Jun 2007 · 6,856 accessesView PDFCite