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52 articles for “LDL”
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Research ArticleOpen accessEvery word in the titleReduced Levels of Testosterone Induce LDL Oxidation and Atherosclerotic Lesions Involving Inflammatory Imbalance and Reduced Macrophage ApoptosisPlacielle Fiorezi Filete, Flávia de Souza Andrade Moraes, Girlandia Alexandre Brasil et al.Atherosclerosis is among the major cardiovascular diseases that cause death in the world. Men who are deficient in androgen hormones are more susceptible to this disease. The aim of this study was to evaluate the influence of reduced levels of testosterone on the lipid profile, pro and anti-inflammatory cytokines, apoptosis of peritoneal macrophages and the development of atherosclerosis in LDLr-/-mice, … …OnLine Journal of Biological Sciences, Vol. 19, Issue 4 · 6 Dec 2019 · 7,338 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleProgressive LDL Reduction to Very Low Levels Improves Dimeric Nitric Oxide Synthase, Nitric Oxide Bioavailability and Reduces Peroxynitrite in Endothelial Cells during HyperglycemiaR. Preston Mason, Hazem Dawoud, Samuel C.R. Sherratt et al.Circulating levels of glucose and LDL influence Endothelial Cell (EC) function in a highly interactive manner as evidenced by nitric oxide production and coupling of endothelial Nitric Oxide Synthase (eNOS) dimer. Here, we report on the status of eNOS function in Human Umbilical Vein Endothelial Cells (HUVECs) cultured under normo- and hyperglycemic (250 mg/dL) condition followed by exposure to increasing … …American Journal of Pharmacology and Toxicology, Vol. 14, Issue 1 · 2 May 2019 · 8,356 accessesView PDFCite
Review ArticleOpen accessIn the keywordsRole of HDL in Atherogenesis: Cholesterol and AtheroprotectionAnastasia Vladimirovna Poznyak, Vasily Nikolaevich Sukhorukov, Victor Yurievich Glanz et al.Atherosclerosis is a major global health burden, responsible for a significant proportion of cardiovascular morbidity and mortality worldwide. Its high prevalence and severe clinical consequences have made it a subject of extensive research. Despite considerable advances, the complexity of its pathogenesis continues to hinder the development of effective preventive strategies and therapeutic interventions. Current evidence implicates chronic inflammation, dysregulated lipid … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 3 Apr 2026 · 1,476 accessesView PDFCite
Review ArticleOpen accessIn the keywordsSubfractions of Low-Density-Lipoprotein: Which is the Most Atherogenic?Anastasia Vladimirovna Poznyak, Vasily Nikolaevich Sukhorukov, Mikhail Аleksandrovich Popov et al.Atherosclerosis is a widespread disease of the arteries, which manifests itself in the narrowing of the lumen of the vessel due to the formation of plaque on its walls. Despite an impressive history of study, atherosclerosis still leaves room for researchers. This is realized due to the complexity of pathogenesis, in which important roles are assigned to a variety of … …OnLine Journal of Biological Sciences, Vol. 23, Issue 4 · 3 Sep 2023 · 4,697 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEffect of Gold Nanoparticles on Serum Lipid Profilein Albino MiceAmmal Esmaeel Ibrahim, Taha Shawi Morad, Dhelal A Shabeeb, Shatha M HasanTriglycerides and lipoproteins are threat features for Cardio Heart Disease. The word “nano” is derived from the Greek word “nanos” which means slight and it is used as introduce for one billionth part (10-9). Conferring to American Society for Testing and Materials. Nanoparticles are those atoms which have two or more than two dimensions and are in the magnitude range … …OnLine Journal of Biological Sciences, Vol. 18, Issue 4 · 31 Oct 2018 · 7,367 accessesView PDFCite
Research ArticleOpen accessIn the keywordsLipid Profile and Antioxidant Enzymes in Normal and Stressed Rat Fed with Palm OleinEqbal M.A. Dauqan, Aminah Abdullah, Halimah Abdullah SaniProblem statement: The objective of the study was to evaluate the effect of Red Palm Olein (RPO) and Palm Olein (PO) on lipid profile and antioxidant enzyme in normal and stressed rat. Approach: Thirty six Sprague Dawley male rats which were randomly divided into six groups of 6 rats per group (tree normal groups and three stressed groups) were treated … …American Journal of Applied Sciences, Vol. 9, Issue 7 · 18 May 2012 · 6,880 accessesView PDFCite
Research ArticleOpen accessIn the keywordsLipid Profile of Gymnasts of the Jordan National TeamAhmad Bani Ata, Kamal Mansi, Talal AburjaiThis study was carried out to assess the lipid pattern in gymnasts of the Jordan National Team. Twelve athletes represent the National gymnastic team (4 males and 8 females, mean age 18±1 year) were included in this study. The training period for them is not less eight years during which they trained 18 hours weekly at least. A group of … …American Journal of Applied Sciences, Vol. 5, Issue 6 · 30 Jun 2008 · 7,531 accessesView PDFCite
Research ArticleOpen accessIn the keywordsStudy the Effects of Ramadan Fasting on the Serum Glucose and Lipid Profile among Healthy Jordanian StudentsKama Mohmoud Saleh MansiRamadan is the holiest month in the Islamic calendar and Muslims fast during this month. We designed this study to evaluate the effect of Ramadan fasting on plasma lipids profile and serum glucose among healthy Jordanian students. Ramadan fasting entails major changes in sleep pattern, physical activity and eating habits, which may cause changes in metabolism both in health and … …American Journal of Applied Sciences, Vol. 4, Issue 8 · 31 Aug 2007 · 8,463 accessesView PDFCite
Research ArticleOpen accessIn the keywordsOxidized Low-density Lipoprotein Upregulates GM2 Activator Protein Gene ExpressionHidekatsu Yanai, Hiroshi Yoshida, Hironobu Fujiwara et al.Oxidized low-density lipoprotein (LDL) has been shown to be a powerful regulator of gene expression in monocyte-derived macrophage. To determine the effects of oxidized LDL on macrophage gene expression, macrophages incubated with native or oxidized LDL were analyzed by differential display technique. The differentially expressed cDNA (387 bp) fragment by oxidized LDL showed 100% homology to the part of 3’-untranslated … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 2 · 30 Jun 2005 · 7,324 accessesView PDFCite
Literature ReviewOpen accessIn the keywordsIntracranial Atherosclerotic Disease: Treatment Potential and Diagnostic OpportunitiesAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina, Anton Yuvenalievich Postnov et al.Atherosclerosis, characterized by the accumulation of atherosclerotic plaques within large arteries, substantially increases the risk of cardiovascular events, including ischemic stroke. Intracranial atherosclerotic disease (ICAD) represents a particularly significant clinical threat given its strong association with ischemic stroke across multiple intracranial arterial territories. This review provides a comprehensive analysis of the pathogenesis, diagnosis, and management of intracranial atherosclerosis. Special attention … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 5 May 2026 · 1,093 accessesView PDFCite