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Research ArticleOpen accessIn the author namesTransforming Growth Factor-β: An Indirect Inducer of Th17 Cell Differentiation both in Human and Murine SystemJ. SchumannSince their first description only some years ago Th17 cells have become of vital importance in immunological research. However, the role of TGF-β in Th17 cell development is still a matter of controversial discussion. Predicted to have a key function in Th17 cell differentiation in the mouse TGF-β was shown to inhibit IL-17 production of human CD4+ T cells. Moreover, … …American Journal of Immunology, Vol. 6, Issue 2 · 30 Jun 2010 · 7,577 accessesView PDF Cite

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