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25 results for “Influenza A Virus”
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Research ArticleOpen accessPhrase in the titleSearching of Main Cause Leading to Severe Influenza A Virus Mutations and Consequently to Influenza Pandemics/EpidemicsGuang Wu, Shaomin YanThe unpredictable mutations in the proteins from influenza A virus lead to the great difficulty in prevention of possible outbreak of bird flu and pandemic/epidemic of influenza. This unpredictability is due to the fact that we know little about the causes that lead to the mutations. In three of our recent studies on the hemagglutinins from influenza A virus, we … …American Journal of Infectious Diseases, Vol. 1, Issue 2 · 30 Jun 2005 · 9,970 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCytokine Expression During the Early Response of A549 Cells to Infection with Influenza Virus, Alphacoronavirus and BetacoronavirusQian Wen Wang, Jae Kyung KimThe escalating incidence of coronavirus infections underscores the critical need for a comprehensive understanding of the differential impacts of Human Coronaviruses (HCoVs) belonging to the Alphacoronavirus and Betacoronavirus genera. This study investigated the varying effects of HCoV-229E (Alphacoronavirus), HCoV-OC43 (Betacoronavirus), and influenza A virus subtype H3N2 on A549 cell viability and cytokine expression. Results showed that H3N2 triggered a more … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 2 · 6 Jul 2024 · 4,554 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDocking and Molecular Dynamics Simulations in Potential Drugs Discovery: An Application to Influenza Virus M2 ProteinMarine E. Bozdaganyan, Philipp S. Orekhov, Nicola L. Bragazzi et al.Molecular docking is a common method for searching new potential drugs. Improvement of the results of docking can be achieved by different ways-one of them is molecular dynamics simulations of protein-ligand complexes. As a model for our research we chose M2 membrane protein from influenza virus. M2 protein is a high selective tetrameric pH-gated proton channel. It was previously shown … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 3 · 11 Nov 2014 · 8,669 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMOLECULAR CHARACTERIZATION ON THE BASIS OF HA, NA AND M GENE REVEALED CHANGES IN CRITICAL AMINO ACID POSITIONS OF INFLUENZA A (H3N2) VIRUS CIRCULATING IN INDIA DURING 2011-2013Sachin Kumar, Shashi Khare, Bano Saidullah et al.Influenza a (H1N1) virus is responsible for acute respiratory infection in human, which occasionally causes epidemic and rarely a pandemic. Full length DNA sequencing of HA, NA and M gene of H3N2 virus from year 2011-2013 was performed for determination of the circulating strains in India along with monitoring status of various mutations associated with drug resistance and virulence. Genetic … …American Journal of Infectious Diseases, Vol. 10, Issue 3 · 18 Oct 2014 · 6,839 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleLevamisole Enhances Cell-Mediated Immune Responses and Reduces Shedding of H9N2 Avian Influenza Virus in Japanese Quails (Coturnix coturnix japonica)Tahoora Shomali, Najmeh Mosleh, Arash AlaeddiniProblem statement: Regarding the role of Japanese quails (Coturnix coturnix japonica) in reassortment and spreading of avian influenza (AI) viruses and inadequate protection of vaccination in this species, the present study aimed to evaluate the effect of levamisole as an immunomodulatory agent on cell-mediated immunity (CMI), antibody responses and shedding of H9N2 AI virus in experimentally infected quails. Approach: On … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 1 · 6 Mar 2012 · 7,651 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleBioactive Compounds Screening from Zingiberaceae Family as Influenza A/Swine Flu Virus Neuraminidase Inhibitor through Docking ApproachUsman Sumo Friend Tambunan, Fadilah, Arli Aditya ParikesitProblem statement: Influenza A/H1N1 is a disease caused by infection of influenza a virus subtype H1N1. It is a major health problem in tropical and subtropical countries. This virus constantly mutates and consequently will be developed into new drug-resistant strains. Approach: In this research, we have conducted docking study to screen bioactive compounds from Zingiberaceae family, which has a role … …OnLine Journal of Biological Sciences, Vol. 10, Issue 4 · 31 Dec 2010 · 8,616 accessesView PDFCite
Case ReportOpen accessIn the keywordsPulmonary Cryptococcosis Complicated by Pneumococcal Pneumonia Co-Infection with Influenza AVirusYoshihiro Kobashi, Daisuke Yoshioka, Shigeki Kato, Toru OgaA 73-year-old man visited Kawasaki Medical School Hospital with complaints of cough and fever persisting for five days. He was diagnosed with myasthenia gravis in 2010 and had received immunosuppressive treatment for eight years. He presented with infiltration shadows in the bilateral middle and lower lung fields. Because both influenza A virus antigen and urinary pneumococcal pneumonia antigen were positive … …American Journal of Infectious Diseases, Vol. 17, Issue 2 · 22 Apr 2021 · 6,383 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAn Informetric Analysis of Studies on Influenza Vaccines and VaccinationVadim Nikolaevich Gureyev, Nikolay Alekseevich Mazov, Tatyana Nikolaevna Ilyicheva, Sergei Ivanovich BazhanInfluenza is one of highly contagious acute virus diseases that primarily affects respiratory ways. Annual seasonal epidemics afflict approximately 15% population worldwide and lead to 250,000–500,000 deaths each year. That is why studies on influenza vaccines and vaccination that prevent spreading of the virus remain highly important. This paper presents the results of informetric analysis of publications on influenza vaccine … …OnLine Journal of Biological Sciences, Vol. 17, Issue 4 · 13 Dec 2017 · 7,274 accessesView PDFCite
Research ArticleOpen accessIn the keywordsSevere and Fatal Influenza Cases in Russia in 2014-2015Svetlana V. Svyatchenko, Alexander G. Durymanov, Ivan M. Susloparov et al.This paper aims to characterize herd immunity of the population inhabiting Asian part of Russia before influenza epidemic and to describe influenza viruses isolated from severe cases including cases with fatal outcomes in the 2014-2015 epidemic season. HI test enabled us to study 3888 serum samples from healthy individuals including 1939 samples collected from poultry farm workers. We showed that … …OnLine Journal of Biological Sciences, Vol. 16, Issue 4 · 24 Dec 2016 · 7,064 accessesView PDFCite
Research ArticleOpen accessIn the keywordsA Novel Glucan-Sulforaphane Combination Stimulates Immune Response to Influenza in Mouse ModelVetvicka Vaclav, Vetvickova JanaInfluenza remains a serious health problem and causes approximately 500,000 deaths world-wide. With current available treatments offering neither dependable protection nor a rapid cure, many have focused their attention to alternative treatments. The aim of this study was to evaluate the possible effect of a novel maitake glucan-sulforaphane combination on immune response against influenza challenge in mice. We evaluated the … …American Journal of Immunology, Vol. 12, Issue 2 · 3 Aug 2016 · 7,933 accessesView PDFCite